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Hampton Inn & Suites St. Louis/South I-55

2.5 star property
St. Louis guestrooms with free WiFi

Choose dates to view prices

Photo gallery for Hampton Inn & Suites St. Louis/South I-55

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board
Indoor pool
Reception
Lobby
Exterior

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Housekeeping
  • Laundry
  • Parking included

Explore the area

View in a map
4200 Midamerica Lane, St. Louis, MO, 63129
  • Mercy Hospital South
    ‪5 min drive‬
  • Grant's Farm
    ‪11 min drive‬
  • River City Casino
    ‪11 min drive‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪34 min drive‬

Room options

View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(26 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(14 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(18 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking | In-room safe, blackout drapes, iron/ironing board

Studio, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.8 out of 10
Exceptional
(34 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed

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Reception

La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis
  • Pool
  • Hot Tub
  • Pet friendly
  • Parking included
3.9 out of 5, Good, 1,006 reviews
$101 nightly
The price is $118
Oct 1 - Oct 2
Total with taxes and fees
La Quinta Inn & Suites by Wyndham St Louis Route 66

About the neighborhood

St. Louis

In St. Louis .At this St. Louis hotel, you'll be within half a mile (1 km) of Barnes Jewish South Campus and 3 miles (5 km) of St Anthony's. Also, Suson Park is within 3 miles (5 km) and Meramec River is within 6 miles (10 km).

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.3 miles
  • Mercy Hospital South - 5 min drive - 2.9 miles
  • Grant's Farm - 11 min drive - 5.9 miles
  • River City Casino - 11 min drive - 7.5 miles
  • Magic House - St. Louis Children's Museum - 13 min drive - 10.5 miles

Getting around

  • Kirkwood Station - 14 min drive
  • St. Louis Lambert Intl. Airport (STL) - 31 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Popeyes Louisiana Kitchen - ‬3 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive
  • ‪Hardee's / Red Burrito - ‬10 min walk

About this property

Hampton Inn & Suites St. Louis/South I-55

St. Louis guestrooms with free WiFi
Hampton Inn & Suites St. Louis/South I-55 offers its guests an indoor pool and a fitness center. A computer station is on site, and both WiFi and wired Internet are free in public spaces. A business center and a meeting room are available. Free breakfast is served daily. Event space at this hotel measures 753 square feet (70 square meters) and includes conference space. Hampton Inn & Suites St. Louis/South I-55 also features a vending machine, coffee/tea in a common area, and complimentary newspapers in the lobby. Self parking is free.
  • 1 building
  • 92 guestrooms or units
  • 5 levels
  • 753 sq ft of conference space
  • 70 sq m of conference space
  • Built in 2010
  • Buffet breakfast (free)
  • Business facilities
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-in
  • Storage area for luggage
  • Front-desk safe
  • Convenience store
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • ATM
  • Elevator
Hampton Inn & Suites St. Louis/South I-55 offers 92 accommodations with safes and coffee/tea makers. 37-inch LCD televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

This St. Louis hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include complimentary weekday newspapers and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

Exterior

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
4.8 out of 5, Exceptional, 1,002 reviews
$118 nightly
The price is $136
Sep 28 - Sep 29
Total with taxes and fees
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenities

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 75 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 pets
  • Pets cannot be left unattended
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, Discover, Carte Blanche, and debit cards. Cash is not accepted. This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

  • Pool access available from 8 AM to 10 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Frequently asked questions

How close is Hampton Inn & Suites St. Louis/South I-55 to the airport?

Hampton Inn & Suites St. Louis/South I-55 is 26.1 mi (31-min drive) away from the St. Louis Lambert Intl. Airport (STL) airport, the closest popular airport to the property.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of Sep 25, 2025, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on Oct 5, 2025 start from $125.41, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Hampton Inn & Suites St. Louis/South I-55 have an airport shuttle?

Airport shuttle services are not available at Hampton Inn & Suites St. Louis/South I-55.

Does Hampton Inn & Suites St. Louis/South I-55 offer free breakfast?

Hampton Inn & Suites St. Louis/South I-55 offers free buffet breakfast every day from 6:00 AM to 10:00 AM.

Is there a casino at Hampton Inn & Suites St. Louis/South I-55?

No, there is no casino at this hotel, but River City Casino (13-min drive) is nearby.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; Check-in end time: midnight.

Is there free parking at Hampton Inn & Suites St. Louis/South I-55?

This hotel offers free self parking.

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Hampton Inn & Suites St. Louis/South I-55 features an indoor pool. Guests can enjoy pool access from 8 AM to 10 PM.

Does Hampton Inn & Suites St. Louis/South I-55 have a spa?

There are no spa services available at this hotel.

How close is Hampton Inn & Suites St. Louis/South I-55 to downtown St. Louis?

Hampton Inn & Suites St. Louis/South I-55 is 1.5 mi away from Tesson Ferry.

Hampton Inn & Suites St. Louis/South I-55 Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 828 out of 1003 reviews
Rating 8 - Good. 126 out of 1003 reviews
Rating 6 - Okay. 27 out of 1003 reviews
Rating 4 - Poor. 6 out of 1003 reviews
Rating 2 - Terrible. 16 out of 1003 reviews

9.8/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Beverly

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The staff here are incredibly professional and friendly, creating a welcoming environment that makes you feel right at home. The rooms are spotless, adding to the overall sense of comfort. The atmosphere is truly delightful! I highly encourage you to experience it for yourself!
Stayed 1 night in Jun 2025

10/10 Excellent

Carl

Business traveler
Nice clean rooms updated.
Stayed 1 night in Jun 2025

10/10 Excellent

Jane

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025

10/10 Excellent

Sandro, Sao Paulo

Liked: Cleanliness, staff & service, property conditions & facilities
Great experience for a weekend in St Louis, the hotel convenience is great, staff very polite in the breakfast and all match with the content in the site, recommend!
Stayed 2 nights in Jun 2025

10/10 Excellent

April Cory

Stayed 1 night in Jun 2025

10/10 Excellent

Lurann K

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
We loved this hotel, other than the rather limited water pressure in the shower. That part could use some improvement. But the hotel itself was clean and the bed very comfortable! I would stay at it again, and I’m just glad I don’t have really thick hair to try to rinse in the shower.
Stayed 1 night in May 2025

10/10 Excellent

Verified traveler

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay

Excellent, even called to see if we left something behind
Stayed 2 nights in May 2025

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quick trip

Needed a hotel for an overnight. This was a great hotel. Very friendly staff and very clean. Good hot breakfast served. Would definitely stay there again if in the area.
Stayed 1 night in May 2025

10/10 Excellent

Joel

Stayed 1 night in May 2025

10/10 Excellent

Natalie

Liked: Cleanliness
Stayed 1 night in May 2025

10/10 Excellent

Ling Hsieu

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

Tracy

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Mar 2025

10/10 Excellent

Darren

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved our stay!

Spacious, clean, quiet room on 4th floor, back side of property. Comfortable, firm bed. Good AC control. Blackout shades. Front desk, housekeeping, and breakfast staff were all courteous and professional. Good coffee and breakfast. Not close to downtown, but plenty of restaurants, groceries, etc. a short drive away. Would def stay again.
Stayed 3 nights in May 2025

10/10 Excellent

Sherry

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

On the way home!

Very nice stay with great service!
Stayed 1 night in May 2025

10/10 Excellent

Mike

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Like any other highway hotel it serves purpose, but we do stay here often. We have family in St. Louis and there are hundreds of choices for hotels. We choose this property brcause of the staff they are always friendly helpful and the hotel is always clean.
Stayed 2 nights in Mar 2025

10/10 Excellent

Angie

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay

Convenient, clean and would stay there again if I needed to
Stayed 2 nights in Feb 2025

10/10 Excellent

Sherry

Stayed 1 night in May 2025

8/10 Good

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in May 2025

10/10 Excellent

Larry

Stayed 1 night in Apr 2025

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Richard

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect

Great hotel
Stayed 2 nights in Apr 2025

10/10 Excellent

Deborah, white bear lake

Stayed 1 night in Apr 2025

10/10 Excellent

Lyndsay

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Rochelle

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Franklin

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Enjoyed our stay and would return.
Stayed 1 night in Mar 2025