Explore 22 Luxury Hotels in Downtown St. Louis

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Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$415 nightly

$485 total

Jan 7 - Jan 8

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,002 reviews)

Didn’t have breakfast

Reviewed on Dec 23, 2025

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

$144 nightly

$168 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.4/10 Exceptional! (3,295 reviews)

good food and cleanroom nice employees

Reviewed on Jan 1, 2026

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$94 nightly

$110 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8.8/10 Excellent! (1,775 reviews)

Room was clean, things were a little outdated but nice for a quick trip. Clean, staff was nice, coke machine and popcorn machine available for free during the day!

Reviewed on Jan 1, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$135 nightly

$158 total

Jan 15 - Jan 16

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,004 reviews)

Clean friendly staff

Reviewed on Jan 1, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

Fully refundableReserve now, pay when you stay

$97 nightly

$115 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,179 reviews)

Great accommodations and I loved the pet friendly environment! Looking forward to trying more of the in-room dining options next time.

Reviewed on Dec 30, 2025

Missouri Athletic Club

405 Washington Ave St. Louis MO

Fully refundableReserve now, pay when you stay

$137 nightly

$161 total

Jan 15 - Jan 16

Total with taxes and fees

This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...

8.6/10 Excellent! (1,002 reviews)

The room was nice and the staff was excellent.

Reviewed on Dec 10, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$157 nightly

$186 total

Jan 15 - Jan 16

Total with taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,006 reviews)

Beautiful hotel. Many places to eat and things to do. Felt safe.

Reviewed on Dec 28, 2025

Le Meridien St. Louis Downtown

1019 Pine St St. Louis MO

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Amazing staff!

Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ...

Reviewed on Jan 25, 2024

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More 4 star hotels in Downtown St. Louis

AC Hotel St. Louis Central West End

215 YORK AVENUE St. Louis MO

$131 nightly

$154 total

Feb 1 - Feb 2

Total with taxes and fees

9/10 Wonderful! (688 reviews)

5 star hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$415 nightly

$485 total

Jan 7 - Jan 8

Total with taxes and fees

9.4/10 Exceptional! (1,002 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.

Downtown St. Louis hotels essential information

Accommodation	566 hotels
Lowest Price	$110
Highest Price	$485
Popular hotels	Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station

Popular Luxury Stays in Downtown St. Louis

5 Stars Luxury stays in Downtown St. Louis

Luxury stays in Downtown St. Louis with spa

Recent Downtown St. Louis Hotel Reviews By Fellow Wanderers

Pear Tree Inn St. Louis Convention Center

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Check in was great, they gave us free parking. Because their hot tub was closed (permanently). 4th level parking, elevators were right there, up 1 level to our room, that was right by the pool and breakfast. Bonus, 530pm was 3 free bar drinks and snacks. Drury really tries to give the customers a quality stay. Rooms were dated, but yet elegant like staying in a rich downtown hotel. Hotel was very clean. ST. Louis Streets were "Crappy", not to far of a walk to the Arch, we did it 2 times in 1 day. Felt safe with a young family, but it was winter and a Sunday. I'll stay again. "

A verified traveler stayed at Pear Tree Inn St. Louis Convention Center