Explore 22 Luxury Hotels in Downtown St. Louis

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Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$485 total

per night

Feb 4 - Feb 5

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,002 reviews)

Our room was excellent. Staff super attentive. Restaurant and bar were outstanding. Will definitely be back again.

Reviewed on Jan 16, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

$153 total

per night

Feb 9 - Feb 10

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.4/10 Exceptional! (3,315 reviews)

The staff was courteous and made me feel welcome. I even got a welcome gift because it was my first time at the Drury.

Reviewed on Jan 29, 2026

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$110 total

per night

Feb 8 - Feb 9

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8.8/10 Excellent! (1,811 reviews)

We stay in this hotel every time we come to St. Louis. Friendly staff. Very clean and comfortable

Reviewed on Jan 31, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$148 total

per night

Feb 5 - Feb 6

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,001 reviews)

The room still had dirty sheets on the floor along with dirty gloves sitting on the side table. They did upgrade our room. Other then that it was a good stay

Reviewed on Jan 22, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

$130 total

per night

Feb 4 - Feb 5

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,222 reviews)

Everything was nice

Reviewed on Feb 1, 2026

Missouri Athletic Club

405 Washington Ave St. Louis MO

$182 total

per night

Feb 17 - Feb 18

This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...

8.6/10 Excellent! (1,000 reviews)

I had a problem with a window in my room at 2 am. They sent a person to fix it right away. In general, the front desk was friendly and helpful.

Reviewed on Jan 16, 2026

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$229 total

per night

Feb 12 - Feb 13

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,001 reviews)

Staff was very friendly and its close to athe Enterprise Center so we didnt have to worry about parking for our event we were going to.

Reviewed on Jan 30, 2026

Le Meridien St. Louis Downtown

1019 Pine St St. Louis MO

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Amazing staff!

Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ...

Reviewed on Jan 25, 2024

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More 4 star hotels in Downtown St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

$236 total

per night

Feb 5 - Feb 6

9/10 Wonderful! (1,000 reviews)

5 star hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$485 total

per night

Feb 4 - Feb 5

9.4/10 Exceptional! (1,002 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.

Downtown St. Louis hotels essential information

Accommodation	577 hotels
Lowest Price	$110
Highest Price	$485
Popular hotels	Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station