Explore 22 Luxury Hotels in Downtown St. Louis

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Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

Fully refundable

$442 nightly

$517 total

May 17 - May 18

Total includes taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,001 reviews)

"To bad hotel has nothing around it"

Reviewed on May 4, 2025

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$120 nightly

$140 total

May 21 - May 22

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.4/10 Exceptional! (2,534 reviews)

"Fun"

Reviewed on May 12, 2025

Pear Tree Inn St. Louis Near Union Station

2211 Market Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$108 nightly

$126 total

May 21 - May 22

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8.8/10 Excellent! (1,413 reviews)

The Pear Tree

"For Once I can honestly say that staying here at the Pear Tree was one of my Better Experiences. As soon as we arrived the desk clerk was a little bit busy but still found the time to check us in . Once he saw that we were pre registered with Hotels . Com . Quincy was his name Immediately got us ..."

Reviewed on May 9, 2025

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Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$104 nightly

$123 total

Jun 8 - Jun 9

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,011 reviews)

"Great location!"

Reviewed on May 12, 2025

Missouri Athletic Club

405 Washington Ave, St. Louis, MO

Fully refundableReserve now, pay when you stay

$141 nightly

$165 total

May 26 - May 27

Total includes taxes and fees

This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...

8.6/10 Excellent! (1,002 reviews)

"Athletic facilities"

Reviewed on May 10, 2025

The Westin St. Louis

811 Spruce St, St. Louis, MO

$135 nightly

$158 total

May 25 - May 26

Total includes taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.4/10 Very Good! (1,001 reviews)

"We love staying at the Westin whenever possible while traveling! The lobby always has that wonderful signature scent! Staff here was courteous and attentive. We checked in with our dog and 5 month old baby and they made sure checkin was smooth and swift. We booked a Non-smoking room, but when made ..."

Reviewed on May 5, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$192 nightly

$228 total

Jun 12 - Jun 13

Total includes taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.2/10 Very Good! (1,003 reviews)

"Loved the lobby bar, with the light show"

Reviewed on May 7, 2025

Le Meridien St. Louis Downtown

1019 Pine St, St. Louis, MO

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Amazing staff!

"Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ..."

Reviewed on Jan 25, 2024

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Downtown St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway, St. Louis, MO

$222 nightly

$262 total

May 25 - May 26

Total includes taxes and fees

8.8/10 Excellent! (1,007 reviews)

5 star hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

$442 nightly

$517 total

May 17 - May 18

Total includes taxes and fees

9.4/10 Exceptional! (1,001 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.

Downtown St. Louis hotels essential information

Accommodation	591 hotels
Lowest Price	$123 total
Highest Price	$517 total
Popular hotels	Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station