Book Hotels in Brussels, IL
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Top Brussels hotels

Pear Tree Inn St. Louis Airport
It was fine
Reviewed on Mar 7, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Good
Reviewed on Mar 6, 2026

Drury Inn & Suites St. Louis Airport
Good stay
Reviewed on Mar 2, 2026

Hollywood Casino & Hotel St. Louis
The room was very clean, staff were friendly, casino was a lot of fun!!! Great place to stay for the weekend or if you are passing through!
Reviewed on Feb 22, 2026

Ameristar Casino Resort and Spa
At first look it was awesome. However taking a deeper look it becomes terrible. First check in is at 4pm and they close the pool at 6pm. Second the tv did not work making it where you had to order movies if you wanted tv. Then after everything when you sign for the 100 deposit if you do not scroll ...
Reviewed on Mar 4, 2026

Renaissance St. Louis Airport Hotel
Yes
Reviewed on Mar 2, 2026

Hilton St. Louis Airport
Shuttle is great and convenient. Runs every 1/2 hour. Hotel is clean and inviting. Bar and food are great! No need to look for a restaurant.
Reviewed on Mar 4, 2026

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Everything met our expectations
Reviewed on Mar 2, 2026

Travelodge by Wyndham St. Louis
The room was dirty and not comfortable. The bed only had one pillow and a super hard head board that you keep hitting your head on during the night. The pillow was not comfortable and felt like it held in heat. The area did not feel safe. I had one of the worst nights of sleep I have ever had at ...
Reviewed on Mar 1, 2026
Brussels Hotel & Travel Guide\n
You may have realized that there are no accommodations options on Travelocity in Brussels. You don't need to stress, because you'll find 2 places to put your feet up an easy drive from Brussels.
The closest Travelocity-listed accommodation option is the Ameristar Casino Resort and Spa, Missouri, 14 miles (22 kilometers) from the downtown core of Brussels. Another handy option is the Embassy Suites St. Louis - St. Charles, situated in Missouri, 13 miles (21 kilometers) from the central area of Brussels.
You could also check out the The Green Tree Inn as well as the Staybridge Suites O'Fallon Chesterfield. The The Green Tree Inn is located only 12 miles (20 kilometers) from central Brussels. The Staybridge Suites O'Fallon Chesterfield, is located just 17 miles (28 kilometers) away. The Residence Inn by Marriott O'Fallon as well as the Sheraton Westport Plaza Hotel St. Louis are other alternative places to book accommodation in Brussels.
Researching so you can go a bit further afield? Southern Illinois has a number of things to see. If you love nature, get ready to discover Southern Illinois's rural landscapes, rolling hills and prairies. You could also venture through its farms. Visitors in this section of United States of America often enjoy rock climbing, hiking and abseiling.
25 miles (40 kilometers) away from Brussels, you will reach Alton, where visitors can enjoy Argosy Casino and Alton Square Mall. The Atrium Hotel and Conference Center and Comfort Inn are just some of the convenient lodging options in Alton. 40 miles (64 kilometers) southeast of Brussels, you'll reach Fairview Heights, which is home to the Holiday Inn St. Louis Fairview Heights and Fairfield Inn by Marriott Fairview Heights. While in Fairview Heights, it's worth visiting the Stonewolf Golf Course and St. Claire Square Mall.
If you can't stop thinking about sport and love attending local games you and your traveling partner should stop by Busch Stadium, which can be found 30 miles (50 kilometers) to the southeast of Brussels. Travelocity customers who would like the ease of booking a bed in the vicinity, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Lambert-St. Louis International Airport is a primary entry point for those flying to Brussels. It is 19 miles (30 kilometers) from the town center. If you choose to stay nearby, look into Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
Frequently asked questions
Recent Brussels hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Airport
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