Explore top 2025 4 Star Hotels in Mississippi Gulf Coast

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Top Mississippi Gulf Coast 4 Star hotels

Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

4 out of 5
777 Beach Blvd., Biloxi, MS
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Sep 7 to Sep 8
$110 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Enjoy the 4 outdoor pools and perks like free self parking and free WiFi. Make the most of the ...
Hard Rock Hotel & Casino Biloxi
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

4 out of 5
850 Bayview Ave, Biloxi, MS
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Sep 7 to Sep 8
$104 total
Sep 7 - Sep 8
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Enjoy a meal in one of the 7 restaurants and free perks like valet parking and WiFi in public ...
IP Casino Resort Spa - Biloxi
Golden Nugget Biloxi

Golden Nugget Biloxi

4 out of 5
151 Beach Blvd, Biloxi, MS
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $81 total per night from Sep 23 to Sep 24
$81 total
Sep 23 - Sep 24
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Business travelers can take advantage of the express check-out. You'll find 4 restaurants ...
Golden Nugget Biloxi
Beau Rivage

Beau Rivage

4 out of 5
875 Beach Blvd, Biloxi, MS
$150 nightly
The price is $168 total per night from Sep 10 to Sep 11
$168 total
Sep 10 - Sep 11
Total with taxes and fees
This resort features a casino, a full-service spa, and 10 restaurants. Relax with a drink at one of the 7 bars/lounges and enjoy perks like free valet parking. ...
Beau Rivage
Palace Casino Resort

Palace Casino Resort

4 out of 5
158 Howard Ave, Biloxi, MS
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Sep 8 to Sep 9
$88 total
Sep 8 - Sep 9
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 5 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Palace Casino Resort
Harrah's Gulf Coast

Harrah's Gulf Coast

4 out of 5
280 Beach Boulevard, Biloxi, MS
$87 nightly
The price is $98 total per night from Sep 8 to Sep 9
$98 total
Sep 8 - Sep 9
Total with taxes and fees
This resort features a casino, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the express check-out and onsite conference space. ...
Harrah's Gulf Coast
Scarlet Pearl Casino Resort

Scarlet Pearl Casino Resort

4 out of 5
9380 Central Ave, D'Iberville, MS
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $133 total per night from Sep 7 to Sep 8
$133 total
Sep 7 - Sep 8
Total with taxes and fees
A casino, 4 restaurants, and an outdoor pool are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas ...
Scarlet Pearl Casino Resort
Doubletree by Hilton Hattiesburg, MS

Doubletree by Hilton Hattiesburg, MS

4 out of 5
10 Gateway Dr, Hattiesburg, MS
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $96 total per night from Oct 5 to Oct 6
$96 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Doubletree by Hilton Hattiesburg, MS
DoubleTree by Hilton Hotel Biloxi

DoubleTree by Hilton Hotel Biloxi

4 out of 5
940 Beach Boulevard, Biloxi, MS
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $125 total per night from Sep 22 to Sep 23
$125 total
Sep 22 - Sep 23
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A business ...
DoubleTree by Hilton Hotel Biloxi
Handsboro Pointe Condo & Suites

Handsboro Pointe Condo & Suites

4 out of 5
1302 Magnolia St, Gulfport, MS
$268 nightly
The price is $300 total per night from Sep 11 to Sep 12
$300 total
Sep 11 - Sep 12
Total with taxes and fees
A seasonal outdoor pool is featured at this apartment, along with a virtual front desk. Take advantage of the free self parking.
Handsboro Pointe Condo & Suites
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4 Star Hotels Mississippi Gulf Coast

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mississippi Gulf Coast 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mississippi Gulf Coast will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mississippi Gulf Coast, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.