Explore 49 Luxury Hotels in Mississippi Gulf Coast
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Best Luxury Hotels in Mississippi Gulf Coast

IP Casino Resort Spa - Biloxi
"The pool wasn’t open was the only thing wrong"
Reviewed on Nov 2, 2026

Margaritaville Resort Biloxi
"Amazing place to stay will stay again looking to book for next year as we speak"
Reviewed on Nov 2, 2026

Beau Rivage

White House Hotel

Golden Nugget Biloxi

Magnolia Inn Townhouse Hattiesburg MS I-59

Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

Microtel Inn & Suites by Wyndham Hattiesburg
More 4 star hotels in Mississippi Gulf Coast

Beachside Biloxi Club Condo: Balcony w/ Ocean View
Mississippi Gulf Coast Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mississippi Gulf Coast luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Mississippi Gulf Coast to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Mississippi Gulf Coast will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mississippi Gulf Coast, and plan your next opulent escape.
Mississippi Gulf Coast hotels essential information
Accommodation | 3,056 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $200 |
Popular hotels | Beau Rivage, Margaritaville Resort Biloxi, White House Hotel, IP Casino Resort Spa - Biloxi, Golden Nugget Biloxi, Magnolia Inn Townhouse Hattiesburg MS I-59, Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination, Microtel Inn & Suites by Wyndham Hattiesburg |
Popular Luxury Stays in Mississippi Gulf Coast
Recent Mississippi Gulf Coast Hotel Reviews By Fellow Wanderers

Margaritaville Resort Biloxi
"Amazing place to stay will stay again looking to book for next year as we speak"











