Explore 49 Luxury Hotels in Mississippi Gulf Coast

Name: Magnolia Inn Townhouse Hattiesburg MS I-59
Price range: $53 total
Rating: 6.8

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Best Luxury Hotels in Mississippi Gulf Coast

Beau Rivage

875 Beach Blvd Biloxi MS

$180 nightly

$202 total

Mar 23 - Mar 24

Total with taxes and fees

This resort features a casino, a full-service spa, and 10 restaurants. Relax with a drink at one of the 7 bars/lounges and enjoy perks like free valet parking. ...

9.2/10 Wonderful! (1,422 reviews)

Rooms were well stocked. Place is always nice and clean. Only issues that i would see would be amount of checkin staff. With this being a heavy visit during the middle of the week due to baseball games, i would have had just a few more staff available to help with checkin.

Reviewed on Mar 12, 2026

White House Hotel

1230 Beach Blvd Biloxi MS

Fully refundableReserve now, pay when you stay

$129 nightly

$145 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public ...

9/10 Wonderful! (1,003 reviews)

As a first-time guest at the White House Hotel, I found the property itself to be very nice. The hotel is clean, comfortable, and has a welcoming atmosphere that makes it a pleasant place to stay. The location and overall appearance of the hotel definitely make a good first impression. However, my ...

Reviewed on Mar 13, 2026

Margaritaville Resort Biloxi

195 Beach Blvd Biloxi MS

Fully refundableReserve now, pay when you stay

$150 nightly

$166 total

Apr 1 - Apr 2

Total with taxes and fees

A water park, 3 restaurants, and a lazy river are all featured at this hotel. Bring the family and enjoy the waterslide, arcade/game room, and kid-friendly dining. ...

8.6/10 Excellent! (5,611 reviews)

Yes

Reviewed on Mar 14, 2026

IP Casino Resort Spa - Biloxi

850 Bayview Ave Biloxi MS

Fully refundableReserve now, pay when you stay

$105 nightly

$118 total

Mar 25 - Mar 26

Total with taxes and fees

This resort features a casino, a full-service spa, and a nightclub. Enjoy a meal in one of the 7 restaurants and free perks like valet parking and WiFi in public ...

8.6/10 Excellent! (5,256 reviews)

Everything was great

Reviewed on Mar 14, 2026

Microtel Inn & Suites by Wyndham Hattiesburg

105 Westover Dr Hattiesburg MS

Fully refundableReserve now, pay when you stay

$64 nightly

$70 total

Mar 22 - Mar 23

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...

8.6/10 Excellent! (1,002 reviews)

Beds and pillows are nice. Staff is so friendly. Room was clean. Breakfast is limited but enough.

Reviewed on Mar 11, 2026

Golden Nugget Biloxi

151 Beach Blvd Biloxi MS

Fully refundableReserve now, pay when you stay

$82 nightly

$90 total

Mar 31 - Apr 1

Total with taxes and fees

This resort features a casino, a full-service spa, and a nightclub. Business travelers can take advantage of the express check-out. You'll find 4 restaurants ...

8/10 Very Good! (2,837 reviews)

My husband and I had an enjoyable stay, however the room we stayed in could benefit from updating the bed. Although it was comfortable, if made annoying sounds the minute we sat on it like loose springs.

Reviewed on Mar 13, 2026

Harrah’s Gulf Coast – A Caesars Rewards Destination

280 Beach Boulevard Biloxi MS

$85 nightly

$95 total

Apr 12 - Apr 13

Total with taxes and fees

This resort features a casino, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the express check-out and onsite conference space. ...

7.6/10 Good! (1,426 reviews)

yes

Reviewed on Mar 13, 2026

Magnolia Inn Townhouse Hattiesburg MS I-59

6655 Highway 49 N. Hattiesburg MS

Fully refundableReserve now, pay when you stay

$48 nightly

$53 total

Mar 19 - Mar 20

Total with taxes and fees

The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...

6.8/10 (619 reviews)

The fridge didn’t work. It’s smelled like mildew. The sheets had hair on them and we got a no smoking room and there were burn holes on the bedding. It was so misleading in regards to the pictures that are online.

Reviewed on Mar 9, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mississippi Gulf Coast

Magnolia Suites BSL

437 Webster St Bay St Louis MS

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10/10 Exceptional! (10 reviews)

Mississippi Gulf Coast Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mississippi Gulf Coast luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mississippi Gulf Coast to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mississippi Gulf Coast will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mississippi Gulf Coast, and plan your next opulent escape.

Mississippi Gulf Coast hotels essential information

Accommodation	3,129 hotels
Lowest Price	$53
Highest Price	$779
Popular hotels	Beau Rivage, Margaritaville Resort Biloxi, White House Hotel, IP Casino Resort Spa - Biloxi, Golden Nugget Biloxi, Magnolia Inn Townhouse Hattiesburg MS I-59, Harrah’s Gulf Coast – A Caesars Rewards Destination, Microtel Inn & Suites by Wyndham Hattiesburg

Popular Luxury Stays in Mississippi Gulf Coast

5 Stars Luxury stays in Mississippi Gulf Coast

Luxury stays in Mississippi Gulf Coast with spa

Recent Mississippi Gulf Coast Hotel Reviews By Fellow Wanderers

IP Casino Resort Spa - Biloxi

5 out of 5

Posted 1 hour ago

Travelocity Verified Review

"Everything was great"

A verified traveler stayed at IP Casino Resort Spa - Biloxi

White House Hotel

3 out of 5

Posted 23 hours ago

Travelocity Verified Review

"As a first-time guest at the White House Hotel, I found the property itself to be very nice. The hotel is clean, comfortable, and has a welcoming atmosphere that makes it a pleasant place to stay. The location and overall appearance of the hotel definitely make a good first impression. However, my experience at check-in could have been better. The desk clerk was polite but not very welcoming or informative. As a first-time guest, I expected a brief overview of the hotel’s amenities, such as the restaurant, bar hours, or other features available to guests. Unfortunately, none of this information was offered during the check-in process. Overall, the hotel itself is a great place to stay, but providing a more informative and welcoming check-in experience would really help enhance the overall guest experience, especially for first-time visitors."

A verified traveler stayed at White House Hotel