Explore 49 Luxury Hotels in Mississippi Gulf Coast

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Best Luxury Hotels in Mississippi Gulf Coast

Beau Rivage

Beau Rivage

875 Beach Blvd Biloxi MS
$131 nightly
The price is $146 total per night from Nov 18 to Nov 19
$146 total
Nov 18 - Nov 19
Total with taxes and fees
This resort features a casino, a full-service spa, and 10 restaurants. Relax with a drink at one of the 7 bars/lounges and enjoy perks like free valet parking. ...
9.4/10 Exceptional! (1,437 reviews)
"I love the beau."

Reviewed on Nov 11, 2026

Opens in a new windowBeau Rivage
White House Hotel

White House Hotel

1230 Beach Blvd Biloxi MS
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 30 to Dec 1
$112 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public ...
9/10 Wonderful! (1,110 reviews)
"This hotel was Beautiful. Everything was clean and the staff was wonderful. We will most definitely be back for a longer stay!!! Restaurant "Cora's" and the bar was exquisite!!"

Reviewed on Nov 10, 2026

Opens in a new windowWhite House Hotel
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

850 Bayview Ave Biloxi MS
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Dec 1 to Dec 2
$110 total
Dec 1 - Dec 2
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Enjoy a meal in one of the 7 restaurants and free perks like valet parking and WiFi in public ...
8.8/10 Excellent! (5,098 reviews)
"Amazing! Clean rooms! Great place."

Reviewed on Nov 12, 2026

Opens in a new windowIP Casino Resort Spa - Biloxi
Microtel Inn & Suites by Wyndham Hattiesburg

Microtel Inn & Suites by Wyndham Hattiesburg

105 Westover Dr Hattiesburg MS
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Nov 22 to Nov 23
$74 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
8.4/10 Very Good! (1,096 reviews)
"Only problem that i saw was no real breakfast try where hit hot be where empty"

Reviewed on Nov 12, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Hattiesburg
Margaritaville Resort Biloxi

Margaritaville Resort Biloxi

195 Beach Blvd Biloxi MS
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $114 total per night from Nov 16 to Nov 17
$114 total
Nov 16 - Nov 17
Total with taxes and fees
A water park, 3 restaurants, and a lazy river are all featured at this hotel. Bring the family and enjoy the waterslide, arcade/game room, and kid-friendly dining. ...
Opens in a new windowMargaritaville Resort Biloxi
Golden Nugget Biloxi

Golden Nugget Biloxi

151 Beach Blvd Biloxi MS
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $77 total per night from Nov 17 to Nov 18
$77 total
Nov 17 - Nov 18
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Business travelers can take advantage of the express check-out. You'll find 4 restaurants ...
Opens in a new windowGolden Nugget Biloxi
Magnolia Inn Townhouse Hattiesburg MS I-59

Magnolia Inn Townhouse Hattiesburg MS I-59

6655 Highway 49 N. Hattiesburg MS
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $64 total per night from Nov 15 to Nov 16
$64 total
Nov 15 - Nov 16
Total with taxes and fees
The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
Opens in a new windowMagnolia Inn Townhouse Hattiesburg MS I-59
Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

280 Beach Boulevard Biloxi MS
$88 nightly
The price is $99 total per night from Dec 13 to Dec 14
$99 total
Dec 13 - Dec 14
Total with taxes and fees
This resort features a casino, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the express check-out and onsite conference space. ...
Opens in a new windowHarrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mississippi Gulf Coast

Mississippi Gulf Coast Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mississippi Gulf Coast luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mississippi Gulf Coast to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mississippi Gulf Coast will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mississippi Gulf Coast, and plan your next opulent escape.


Mississippi Gulf Coast hotels essential information

Accommodation
3,050 hotels
Lowest Price
$64
Highest Price
$201
Popular hotels
Beau Rivage, Margaritaville Resort Biloxi, White House Hotel, IP Casino Resort Spa - Biloxi, Golden Nugget Biloxi, Magnolia Inn Townhouse Hattiesburg MS I-59, Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination, Microtel Inn & Suites by Wyndham Hattiesburg

Popular Luxury Stays in Mississippi Gulf Coast

Recent Mississippi Gulf Coast Hotel Reviews By Fellow Wanderers