Explore the best 2025 4 Star Hotels Hotels in Central United States

Name: Margaritaville Beach Resort South Padre Island
Price range: $233 total

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Top Central United States 4 Star hotels

The San Luis Resort, Spa & Conference Center

5222 Seawall Blvd, Galveston, TX

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A full-service spa, 3 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 4 outdoor tennis courts, and relax with drinks at the bar/lounge and poolside bar.

Pool

Spa

InterContinental Chicago Magnificent Mile by IHG

505 N Michigan Ave, Chicago, IL

$231 nightly

$266 total

Aug 10 - Aug 11

Total includes taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a gym. Enjoy the steam room and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.

Pool

Spa

Swissotel - Chicago

323 E Wacker Dr, Chicago, IL

Free Cancellation

Reserve now, pay when you stay

$216 nightly

$254 total

Aug 7 - Aug 8

Total includes taxes and fees

This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the business center, express check-in, and valet parking. A restaurant, a 24-hour front desk, and laundry facilities are also provided.

Spa

Pet friendly

Bourbon Orleans Hotel

717 Orleans St., New Orleans, LA

Free Cancellation

Reserve now, pay when you stay

$119 nightly

$140 total

Jul 29 - Jul 30

Total includes taxes and fees

This hotel features an outdoor pool, a gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Valet parking, a coffee shop, and a computer station are also offered.

Pool

Pet friendly

Hilton Chicago O'Hare Airport

O'Hare International Airport, Chicago, IL

Free Cancellation

Reserve now, pay when you stay

$179 nightly

$210 total

Aug 8 - Aug 9

Total includes taxes and fees

This hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. You'll appreciate the area shuttle, valet parking, and coffee shop/cafe.

Gaylord Opryland Resort & Convention Center

2800 Opryland Drive, Nashville, TN

Free Cancellation

Reserve now, pay when you stay

$397 nightly

$466 total

Aug 2 - Aug 3

Total includes taxes and fees

This smoke-free resort features a full-service spa, a water park, and 18 restaurants. Traveling on business? Take advantage of the business center, express check-out, and valet parking. Enjoy a meal in one of the 2 coffee shops/cafes and perks like a free area shuttle.

Pool

Hot Tub

Embassy Suites by Hilton Chicago Downtown River North

600 N State St, Chicago, IL

Free Cancellation

Reserve now, pay when you stay

$211 nightly

$247 total

Aug 10 - Aug 11

Total includes taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and free full breakfast each morning. Valet parking, a business center, and a grocery/convenience store are also offered.

Pool

Breakfast included

The Westin Michigan Avenue Chicago

909 North Michigan Ave, Chicago, IL

Free Cancellation

Reserve now, pay when you stay

$194 nightly

$228 total

Aug 6 - Aug 7

Total includes taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the gym, bar/lounge, and coffee shop.

Spa

Pet friendly

Fairmont Chicago at Millennium Park

200 North Columbus Drive, Chicago, IL

Free Cancellation

Reserve now, pay when you stay

$254 nightly

$298 total

Aug 8 - Aug 9

Total includes taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this eco-certified hotel. Families will appreciate the onsite laundry facilities and in-room childcare. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi.

Spa

Pet friendly

citizenM Chicago Downtown

80 East Wacker Place, Chicago, IL

$165 nightly

$194 total

Aug 11 - Aug 12

Total includes taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. A coffee shop, a communal living room, and express check-in are also on offer.

Free WiFi

Restaurant

Hyatt Regency O'Hare Chicago

9300 Bryn Mawr Ave, Rosemont, IL

Free Cancellation

Reserve now, pay when you stay

$152 nightly

$173 total

Jul 21 - Jul 22

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Self parking, a coffee shop, and limo/town car service are also offered.

Free airport shuttle

Pet friendly

Margaritaville Beach Resort South Padre Island

310 Padre Blvd, South Padre Island, TX

Free Cancellation

Reserve now, pay when you stay

$199 nightly

$233 total

Aug 10 - Aug 11

Total includes taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-out, laundry service, and valet parking. You'll appreciate the gym, bar/lounge, and laundry facilities.

Pool

Spa

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4 Star Hotels Central United States

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Central United States 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Central United States will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Central United States, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Central United States hotels essential information

Accommodation	292,293 hotels
Lowest Price	$140
Highest Price	$466
Popular hotels	The San Luis Resort, Spa & Conference Center, InterContinental Chicago Magnificent Mile by IHG, Swissotel - Chicago, Bourbon Orleans Hotel, Hilton Chicago O'Hare Airport, Gaylord Opryland Resort & Convention Center, Embassy Suites by Hilton Chicago Downtown River North, The Westin Michigan Avenue Chicago, Fairmont Chicago at Millennium Park, citizenM Chicago Downtown, Hyatt Regency O'Hare Chicago, Margaritaville Beach Resort South Padre Island