Book Hotels in Wykoff, MN
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Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$109 nightly
The price is $125 total per night from Apr 4 to Apr 5
$125 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very clean. Ɓed was way too soft. The dining menu was limited but good. Had 3 meals there and were very satisfied. Servers were all incredible.
Reviewed on Mar 25, 2026

Spark by Hilton Rochester South
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Apr 12 to Apr 13
$84 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
We really enjoy staying here every time we visit the Mayo! The staff is very friendly, the hotel is clean and quiet, breakfast is always good and fresh, and there’s always complementary bananas in the lobby!
Reviewed on Mar 31, 2026

Aspen Suites
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Apr 2 to Apr 3
$175 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Room was clean and comfy. Hotel staff were nice and helpful.
Reviewed on Mar 29, 2026

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Apr 10 to Apr 11
$108 total
Apr 10 - Apr 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The room was clean and the staff was very helpful
Reviewed on Mar 28, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Apr 2 to Apr 3
$172 total
Apr 2 - Apr 3
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Rooms are clean and in good shape, but age of the hotel is showing.
Reviewed on Mar 31, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Apr 5 to Apr 6
$108 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
The hotel was nicely located to stores and restaurants. However, the evening attendant was sleeping when we tried to check in. In addition, the room itself was not kept up. The tub was chipping and looked unclean. The bed was lumpy and very uncomfortable. In addition, the headboard and remote had ...
Reviewed on Mar 30, 2026

Aspen Select
1215 2nd St SW Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Apr 1 to Apr 2
$151 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Aspen Select is a solid choice near St Mary's hospital. The staff are kind and attentive and although the outside may not be as new as other options, the rooms are comfortable with pullouts and recliners and amenities.
Reviewed on Mar 20, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Apr 1 to Apr 2
$178 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Staff was very friendly. Breakfast was good and fresh.
Reviewed on Mar 31, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$93 nightly
The price is $107 total per night from Apr 4 to Apr 5
$107 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Kahler Grand Hotel
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Rooms are clean and in good shape, but age of the hotel is showing."
A verified traveler stayed at Kahler Grand Hotel
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