Book Hotels in Wykoff, MN
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$130 nightly
The price is $149 total per night from Jun 21 to Jun 22
$149 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The pool was closed, the made to Oder breakfast was not very good. Hotel was clean and the staff was friendly!"
Reviewed on Jun 10, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jun 17 to Jun 18
$195 total
Jun 17 - Jun 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"1"
Reviewed on Jun 8, 2026

Hampton Inn Rochester-South
1755 S Broadway Rochester MN
$79 nightly
The price is $91 total per night from Jul 4 to Jul 5
$91 total
Jul 4 - Jul 5
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
"Room was fairly clean. A lot of hair in the drain. Some yellowing in corners of the tub/shower area and some stains on the walls if you look around. Normal wear and tear. Overall, I felt the room was clean but could use a quick detailing. Breakfast options were good. The sausage and potatoes were ..."
Reviewed on Jun 13, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$112 nightly
The price is $129 total per night from Jun 20 to Jun 21
$129 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Great staff, location, and onsite bar/restaurant! Only dislike was the parking ramp system with the QR code."
Reviewed on Jun 9, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jun 21 to Jun 22
$131 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"The restaurant I’d first rate. The provided transportation to and from Mayo and surrounding area was first rate. The colonial breakfast was good. The staff support was first rate. The price was a good value. The condition of the hotel was just ok."
Reviewed on Jun 14, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $174 total per night from Jun 19 to Jun 20
$174 total
Jun 19 - Jun 20
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"I usually stay at another hotel for my Mayo Clinic appointments and treatment but it was full so I booked at Kaylee Grand due to convenience. When I checked in, all seemed fine until we got to our room. The state of the bathroom was disgusting! Massive amounts of hair on the floor and in the bathtub. ..."
Reviewed on Jun 14, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $183 total per night from Jun 15 to Jun 16
$183 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"The room was clean and comfortable, the staff was friendly and helpful, the breakfast was wonderful, and the parking was deeply appreciated. No question that next time, and there will be one, we'll stay at the Kahler Inn."
Reviewed on Jun 11, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jun 16 to Jun 17
$91 total
Jun 16 - Jun 17
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"The pool was really dirty. On the side of the side of the pool, you could see people scratching their initials in it through the scum. I was on the first floor and the carpet was damp because of all the condensation while it was really warm or it was leaking or something. The beds weren’t comfortable. ..."
Reviewed on Jun 13, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Jun 21 to Jun 22
$84 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Breakfast was just like any other hotel."
Reviewed on Jun 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
4 out of 5
Posted 7 hours ago
Travelocity Verified Review
"The restaurant I’d first rate. The provided transportation to and from Mayo and surrounding area was first rate. The colonial breakfast was good. The staff support was first rate. The price was a good value. The condition of the hotel was just ok."
A verified traveler stayed at Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Explore More Ways to Travel with Travelocity
- Hotels near Rochester Community and Technical College
- Hotels near Apache Mall
- Hotels near Old Barn Resort Course
- St. Charles Hotels
- Hotels near Olmsted County Fairgrounds
- Rochester Hotels
- Hotels near Forestville Mystery Cave State Park
- Hotels near Mayo Clinic
- Hotels near Niagara Cave
- B&B in Stewartville
- Cottages in Stewartville
- Extended Stay Hotels in Stewartville
- Stewartville Hotels
- Motels in Stewartville
- Farmstay in Lanesboro
- Apartments in Lanesboro
- B&B in Lanesboro
- Cabins in Lanesboro
- Cottages in Lanesboro
- Golf Resorts & in Lanesboro
- Spa Resorts & in Lanesboro
- Lanesboro Hotels
- Inns in Lanesboro
- Motels in Lanesboro
- Vacation Homes in Lanesboro
- Villas in Lanesboro
- B&B in Whalan
- Cabins in Whalan
- Guest Houses in Whalan
- Whalan Hotels
- Inns in Whalan
- Lodges in Whalan
- Villas in Whalan
- B&B in Preston
- Cabins in Preston
- Guest Houses in Preston
- Kid Friendly Hotels in Preston
- Hotels with Pools in Preston
- Preston Hotels
- Motels in Preston
- Le Roy Hotels
- Hotels near Regional Sports Center
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Peterson Hotels
- Motels in Grand Meadow
- B&B in Harmony
- Cabins in Harmony
- Extended Stay Hotels in Harmony
- Harmony Hotels
- 4 Star Hotels in Spring Valley
- Farmstay in Spring Valley
- Apartments in Spring Valley
- Cabins in Spring Valley
- Condos in Spring Valley
- Extended Stay Hotels in Spring Valley
- Spring Valley Hotels
- Vacation Homes in Spring Valley
- Hotels near Rochester Intl.
- Hotels near Soldiers Field Golf Course
- Canton Hotels
- Hotels near Plummer House
- Hotels near Deer Creek Speedway
- Hotels near Root River
- Eyota Hotels
- B&B in Chatfield
- Cabins in Chatfield
- Extended Stay Hotels in Chatfield
- Chatfield Hotels
- Motels in Chatfield
- Vacation Homes in Chatfield
- Hotels near Lanesboro Arts Center
- Hotels near Commonweal Theatre Company
- Hotels near Four Daughters Vineyard & Winery
- Flights to Harmony
- Flights from Rochester Intl.
- American Airlines Dallas (DFW) to Rochester (RST) flights
- Delta Detroit (DTW) to Rochester (RST) flights
- Delta Minneapolis (MSP) to Rochester (RST) flights
- Flights from Denver (DEN) to Rochester (RST)
- Flights from Des Moines (DSM) to Rochester (RST)
- Flights from Grand Rapids (GRR) to Rochester (RST)
- Flights from Kansas City (MCI) to Rochester (RST)
- Flights from Orlando (MCO) to Rochester (RST)
- Flights from Minneapolis (MSP) to Rochester (RST)
- Flights from Omaha (OMA) to Rochester (RST)
- Flights from Chicago (ORD) to Rochester (RST)
- Flights from Portland (PDX) to Rochester (RST)
- Flights from Phoenix (PHX) to Rochester (RST)
- Flights from Rapid City (RAP) to Rochester (RST)
- Flights from St. Louis (STL) to Rochester (RST)
- Flights to Chatfield






