Book Hotels in Wykoff, MN
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Top Wykoff hotels

Friendly-Farm Retreat
Wykoff
This apartment includes a garden and barbecue grills.
"Wonderful spot close to everything the root river provides."
Reviewed on Jun 11, 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $90 total per night from Aug 3 to Aug 4
$90 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
"Very nice property, quiet area off the main road through Rochester. Would have been nice if they had more of a patio for outdoor seating. There were a couple tables outside the pool but were taken by several other groups so we made due with some chairs and a bench. There were softball games and pro ..."
Reviewed on Jul 15, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
$125 nightly
The price is $144 total per night from Jul 27 to Jul 28
$144 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"The room was clean and spacious, beds were comfortable and it had a little kitchenette. The parking garage was full, and we had to park on the street where we could see broken bottles and intoxicated people walking around. It wasn’t the safest area to leave a vehicle."
Reviewed on Jul 12, 2025

Aspen Select
1215 2nd St SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Jul 23 to Jul 24
$151 total
Jul 23 - Jul 24
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"The hotel was quiet and the room was clean with all standard amenities. The bed was comfortable and the rooms were affordable. The only drawback is very limited space to pull into the hotel drop off and almost no parking available."
Reviewed on Jul 18, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $131 total per night from Aug 3 to Aug 4
$131 total
Aug 3 - Aug 4
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Checking in is great rooms new a lot of updating!"
Reviewed on Jul 19, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $90 total per night from Jul 27 to Jul 28
$90 total
Jul 27 - Jul 28
Total includes taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"With my husband i felt safe enuf, but alone coming in the back, which is closest to my room, not so much. About 5 miles from Mayo but easy access there from hotel."
Reviewed on Jul 18, 2025

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Aug 8 to Aug 9
$92 total
Aug 8 - Aug 9
Total includes taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"It is an average hotel. Is also old, carpet and walls need to be updated. You get what you pay. It was not that expensive hotel. So, i guess is worth the money."
Reviewed on Jul 22, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $127 total per night from Aug 21 to Aug 22
$127 total
Aug 21 - Aug 22
Total includes taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Good place to stay and an ok price."
Reviewed on Jul 19, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Jul 27 to Jul 28
$83 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
"bathtub needs updating"
Reviewed on Jul 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Med City Inn & Suites - Mayo Clinic Area
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"It is an average hotel. Is also old, carpet and walls need to be updated. You get what you pay. It was not that expensive hotel. So, i guess is worth the money."
A verified traveler stayed at Med City Inn & Suites - Mayo Clinic Area
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