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Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$116 nightly
The price is $133 total per night from Apr 3 to Apr 4
$133 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very nice place to stay at and very close to the mayo clinic

Reviewed on Mar 12, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Mar 22 to Mar 23
$79 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
Quick check in, nice room. Insulation is lacking so be prepared to hear your neighbors. Breakfast has a lot of high carb options, so if you’re looking for a protein breakfast, you’ll likely need to eat offsite.

Reviewed on Mar 14, 2026

Opens in a new windowSpark by Hilton Rochester South
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Mar 18 to Mar 19
$175 total
Mar 18 - Mar 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Great amenities

Reviewed on Mar 13, 2026

Opens in a new windowAspen Suites
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$90 nightly
The price is $104 total per night from Apr 3 to Apr 4
$104 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Nice room

Reviewed on Mar 10, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3 out of 5
1125 2nd St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Mar 21 to Mar 22
$108 total
Mar 21 - Mar 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Pros: affordable, staff willing to help and breakfast Cons: bathroom flooring buckling, no pool towels (asked for some but out), hot tub was warm but not working and stains on the furniture.

Reviewed on Mar 11, 2026

Opens in a new windowSpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Mar 15 to Mar 16
$146 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
For the price parking should be cheaper and breakfast should be free, especially since most people are staying here for medical reasons

Reviewed on Mar 13, 2026

Opens in a new windowKahler Grand Hotel
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Mar 16 to Mar 17
$91 total
Mar 16 - Mar 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
The entire property smelled strongly of chlorine from the pool. That included in our room. My friend had irritated eyes and sinuses from it. I had a bad headache. It's a nice property with a great staff, but something needs to be done about the smell.

Reviewed on Mar 13, 2026

Opens in a new windowBest Western Rochester Hotel Mayo Clinic Area/St. Mary's
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Mar 22 to Mar 23
$84 total
Mar 22 - Mar 23
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Good place to stay

Reviewed on Mar 12, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Mar 15 to Mar 16
$152 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Very clean, nice breakfast and convenient to the clinic via walking subway.

Reviewed on Mar 13, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Wykoff?
From well-thought-out amenities to extra space, kid-friendly hotels come with features that can help turn a regular family vacation into a fantastic one. These Wykoff properties make vacationing with little ones easy: The entire crew will love staying at Welcoming mid-century modern history-friendly home in bluff county.. A playground and a king bed are among the things that help make this hotel a sought-after option. Otherwise, spend your Wykoff break at Friendly-Farm Retreat. Make the most of a playground, a king bed and more here.
Where can I find cheap hotels in Wykoff?
At Travelocity you'll find really nice hotels in Wykoff at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Wykoff rather than in Wykoff. We may find you even better rates, too.
How do I find the best Wykoff hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Wykoff then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Wykoff?
The cheapest hotel in Wykoff is $79. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Wykoff?
There are 328 hotels in Wykoff on Travelocity.
What are the best hotels in Wykoff?
Wykoff has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Wykoff for you!
When is the best time to visit Wykoff?
If you want the joy of a fun-filled trip in peak season, visit Wykoff during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Wykoff?
Based on historic data is usually the cheapest month to visit Wykoff. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Wykoff?
There are multiple hotels in Wykoff that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Wykoff. We have plenty of kid-friendly hotels in Wykoff to choose from on Travelocity!
Why book a hotel in Wykoff through Travelocity?
Because we have the top hotels in Wykoff! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Wykoff on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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