Book Hotels in Wykoff, MN
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Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$116 nightly
The price is $133 total per night from Jun 13 to Jun 14
$133 total
Jun 13 - Jun 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The pool was closed, the made to Oder breakfast was not very good. Hotel was clean and the staff was friendly!"
Reviewed on Jun 10, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jun 13 to Jun 14
$195 total
Jun 13 - Jun 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"1"
Reviewed on Jun 8, 2026

Hampton Inn Rochester-South
1755 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jul 3 to Jul 4
$91 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
"Very clean Good coffee Good hot tub Shuttle to Mayo Great place"
Reviewed on Jun 9, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$112 nightly
The price is $129 total per night from Jun 20 to Jun 21
$129 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Great staff, location, and onsite bar/restaurant! Only dislike was the parking ramp system with the QR code."
Reviewed on Jun 9, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Jun 17 to Jun 18
$128 total
Jun 17 - Jun 18
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Very nice and convenient to Mayo. Staff very helpful. Nice breakfast."
Reviewed on Jun 10, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $167 total per night from Jul 2 to Jul 3
$167 total
Jul 2 - Jul 3
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Hotel was beautiful. Super Convenient for our Mayo appointments, pool at night sSUPER cool, but pool room could use some work."
Reviewed on Jun 11, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jun 17 to Jun 18
$87 total
Jun 17 - Jun 18
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Good stuff"
Reviewed on Jun 10, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Jun 14 to Jun 15
$84 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Staff was fantastic, beds super comfy. Shower was pretty bad, it was like a garden hose with a kink and only one “spray” setting which was at bare minimum a mist. Ladies, skip the conditioner. The water softener I’m guessing has so much salt it leaves you feeling greasy. Breakfast was good and coffee ..."
Reviewed on Jun 10, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $165 total per night from Jun 17 to Jun 18
$165 total
Jun 17 - Jun 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Kahler Grand Hotel
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Hotel was beautiful. Super Convenient for our Mayo appointments, pool at night sSUPER cool, but pool room could use some work."
A verified traveler stayed at Kahler Grand Hotel
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