Book Hotels in Wykoff, MN
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Top Wykoff hotels

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Nov 27 to Nov 28
$160 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"If you want a full breakfast you'd better get up right when they serve because if they run out of things they will yell you like they told me, no, we will not be putting out more. It was 30 mn before the end if breakfast and there were no potatoes, 5 pieces left which I took 2 because there was a ..."
Reviewed on Oct 29, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Nov 6 to Nov 7
$131 total
Nov 6 - Nov 7
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"We had a fantastic stay at Centerstone Plaza Hotel! The rooms were clean, spacious and comfortable, the staff was friendly and welcoming, and the overall experience was excellent. We would definitely stay here again. Highly recommended!!"
Reviewed on Nov 1, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $173 total per night from Dec 3 to Dec 4
$173 total
Dec 3 - Dec 4
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"My room 820 had a shower where the water temperature was impossible to adjust, The water temperature varied from ice cold to scalding hot while not turning the either the hot or cold water faucets. Taking a shower was almost impossible."
Reviewed on Nov 1, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $96 total per night from Dec 1 to Dec 2
$96 total
Dec 1 - Dec 2
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"It was nice and quite"
Reviewed on Oct 31, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $87 total per night from Nov 8 to Nov 9
$87 total
Nov 8 - Nov 9
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $163 total per night from Dec 3 to Dec 4
$163 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...

Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $138 total per night from Nov 5 to Nov 6
$138 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$97 nightly
The price is $112 total per night from Nov 28 to Nov 29
$112 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

The Berkman
217 14th Ave SW Rochester MN
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $241 total per night from Dec 1 to Dec 2
$241 total
Dec 1 - Dec 2
Total with taxes and fees
This aparthotel features a gym and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a 24-hour business center, and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Kahler Grand Hotel
5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"My room 820 had a shower where the water temperature was impossible to adjust, The water temperature varied from ice cold to scalding hot while not turning the either the hot or cold water faucets. Taking a shower was almost impossible."
A verified traveler stayed at Kahler Grand Hotel
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