Book Hotels in Wykoff, MN
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Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$121 nightly
The price is $139 total per night from Jul 31 to Aug 1
$139 total
Jul 31 - Aug 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Very friendly staff and conventily located!"
Reviewed on Jul 1, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jul 3 to Jul 4
$195 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"The good: Clean room, comfortable bed, very kind staff, great breakfast, convenient parking garage. The bad: Wall outlets in the room were all very loose and nothing would stay plugged in (the weight of the plug would cause it to fall out). There were no bath towels in the room (I assume the cleaning ..."
Reviewed on Jul 1, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jul 12 to Jul 13
$131 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"We've stayed here in the past for Mayo appointments, but this time was bad. The air conditioner barely worked. The room was so humid, the carpet felt wet and the bathroom door was swelled and wouldn't shut. The window had fingerprints all over it, so you wonder how clean the room was. If you stay ..."
Reviewed on Jul 1, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $148 total per night from Jul 6 to Jul 7
$148 total
Jul 6 - Jul 7
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"The only thing is good for me is the location it’s the the closest to the hospital"
Reviewed on Jul 1, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jul 12 to Jul 13
$91 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
"The entire hotel was so hot and humid on the inside. You could barely breathe just walking through to get to your room. So hot, that it fogged up my glasses the second I stepped into the hallway and outside from checking in. There was no place to hang up your towel, other than the shower curtain ..."
Reviewed on Jun 30, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Jul 10 to Jul 11
$160 total
Jul 10 - Jul 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"!"
Reviewed on Jul 1, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jul 3 to Jul 4
$97 total
Jul 3 - Jul 4
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"The room was very clean. Excellent stay for the price."
Reviewed on Jun 30, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $87 total per night from Jul 12 to Jul 13
$87 total
Jul 12 - Jul 13
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Black mold in the window wells. A/C didn't work well and didn't at all in the halls or lobby and breakfast area."
Reviewed on Jun 30, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 12 to Jul 13
$87 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"My go to hotel in Rochester now. Always excellent in all areas"
Reviewed on Jul 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

EVEN Hotel Rochester - Mayo Clinic Area by IHG
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Very friendly staff and conventily located!"
A verified traveler stayed at EVEN Hotel Rochester - Mayo Clinic Area by IHG
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