Book Hotels in Picayune, MS
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Top Picayune hotels

Drackett House by Whiskey Properties
"Such an awesome place I love it here. The new pool is a great addition to the property. I will be back. I’ve been here several times. Great location great place to stay.!!!"
Reviewed on Aug 13, 2026

Silver Slipper Casino & Hotel - Adults Only
"I was looking forward to the hot tub....but it was VERY DIFFICULT TO GET IN AND OUT. THERE ARE NO STEPS TO LOWER YOU IN ? AND YOU PLOP IN FROM THE TOP. AND GETTING OUT YOU NEED SPIDER STRONG LEGS WHILE GRABBING THE BAR☆▪︎¤¿?"
Reviewed on Aug 13, 2026

Comfort Inn & Suites Slidell - New Orleans Area
"It was very comfortable."
Reviewed on Aug 11, 2026

Hollywood Casino Gulf Coast
"I’d opt to stay at another property!"
Reviewed on Aug 13, 2026

Holiday Inn Express Picayune-Stennis Space Center by IHG

Ramada by Wyndham Diamondhead I-10/Gulfport

Pass Bungalows

Quality Inn Slidell I-10

Holiday Inn Express Slidell by IHG
Cheap Picayune hotels

Super 8 by Wyndham Picayune
Picayune Hotel & Travel Guide\n
If the world is your oyster, find a hidden pearl in the small city of Picayune, Mississippi. Located in Pearl River County, its name means “small coin” in Spanish and holds much more value for explorers than its nearness to New Orleans. Watch birds take flight above the mysterious swamp as you inhale the sweet scent of magnolias and it’ll be hard to believe you're just minutes from the neon lights of the Big Easy.
Visiting Picayune
When your plane lands at the Louis Armstrong International Airport, about 60 miles from Picayune, you’ll see verdant greenery all around and smell the salty tang of the bayou's brackish waters as you head to your destination. A range of Picayune hotel deals free up the budget of curious adventurers like yourself for more exploration in this new city. Step back in time on East Canal Street by roaming through musty antique shops full of hidden treasures. Feel the oiled wood of a colonial antique birdcage, or pick up an alligator head dating back more than a century. Sate your inner foodie along West Canal Street, where you can linger over a Southern-style brunch, washing down hearty biscuits and sausage gravy with a grapefruit mimosa.
Reserving a Picayune car rental lets you partake in the traditions of Bourbon Street revelry within minutes. Spend a night at one of the famous (or infamous) hotels in New Orleans, stepping right outside your front door and following the sound of live music. Guitar riffs in the air might lead you to a dive bar with cheap beer or an upscale lounge serving the famed NOLA hurricane cocktails. If you don't want to stay in the Big Easy, head back to one of the comfortable, affordable Picayune hotels.
Find what pearls await in the South by booking hotels in Picayune through Travelocity. With our Price Guarantee, we'll match any lower prices or refund the difference, getting you the best possible deals.
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Recent Picayune hotel reviews by fellow wanderers

Silver Slipper Casino & Hotel - Adults Only
"I was looking forward to the hot tub....but it was VERY DIFFICULT TO GET IN AND OUT. THERE ARE NO STEPS TO LOWER YOU IN ? AND YOU PLOP IN FROM THE TOP. AND GETTING OUT YOU NEED SPIDER STRONG LEGS WHILE GRABBING THE BAR☆▪︎¤¿?"
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