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Top hotels in Mayo Clinic

Hotel Valley Ho

Hotel Valley Ho

4.5 out of 5
6850 E Main St Scottsdale AZ
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from May 31 to Jun 1
$133 total
May 31 - Jun 1
Total with taxes and fees
A full-service spa, 2 outdoor pools, and a 24-hour gym are all featured at this luxury resort. Traveling on business? Take advantage of the business center, ...
Hotel was great loved the restaurant and bar area. Pool was fun and happening with the DJ playing. Drinks were yummy. Loved the location of the hotel and the valet was awesome. Would definitely recommend.

Reviewed on May 3, 2026

Opens in a new windowHotel Valley Ho
Talking Stick Resort

Talking Stick Resort

4 out of 5
9800 E. Talking Stick Way Scottsdale AZ
$184 nightly
The price is $210 total per night from Jun 1 to Jun 2
$210 total
Jun 1 - Jun 2
Total with taxes and fees
This resort features a golf course, a casino, and a full-service spa. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
We really enjoyed our first staycation at Talking Sticks resort. The room was spacious and clean. The bed was comfortable. The bathroom was clean and well appointed. The walk-in shower had a rain faucet in the ceiling that could have been larger but it was adequate. We really enjoyed the view from ...

Reviewed on May 3, 2026

Opens in a new windowTalking Stick Resort
FOUNDRE Phoenix

FOUNDRE Phoenix

4 out of 5
1100 N Central Avenue Phoenix AZ
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $196 total per night from May 6 to May 7
$196 total
May 6 - May 7
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
Enjoyed my stay, the place looked great and great view

Reviewed on May 3, 2026

Opens in a new windowFOUNDRE Phoenix
Kimpton Miralina Resort & Villas by IHG

Kimpton Miralina Resort & Villas by IHG

4 out of 5
7200 N Scottsdale Rd Paradise Valley AZ
Fully refundable
$187 nightly
The price is $211 total per night from Jun 3 to Jun 4
$211 total
Jun 3 - Jun 4
Total with taxes and fees
This luxury resort features a full-service spa, 6 outdoor pools, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi ...
Our room had two bathrooms & 2 showers!!! Had no idea…that was a great bonus.

Reviewed on May 3, 2026

Opens in a new windowKimpton Miralina Resort & Villas by IHG
Hilton Phoenix Tapatio Cliffs Resort

Hilton Phoenix Tapatio Cliffs Resort

4 out of 5
11111 N 7th St Phoenix AZ
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $177 total per night from May 24 to May 25
$177 total
May 24 - May 25
Total with taxes and fees
This Mediterranean resort features a golf course, free water park access, and a full-service spa. Bring the family and enjoy the waterslide and kid-friendly ...
Pool was a little cold but warmed up after being in it for a bit. Room was clean.

Reviewed on May 3, 2026

Opens in a new windowHilton Phoenix Tapatio Cliffs Resort
Arizona Grand Resort & Spa

Arizona Grand Resort & Spa

4 out of 5
8000 S. Arizona Grand Parkway Phoenix AZ
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $242 total per night from May 25 to May 26
$242 total
May 25 - May 26
Total with taxes and fees
This smoke-free resort features a golf course, free water park access, and a full-service spa. Bring the family and enjoy the lazy river, children's pool, and ...
Excellent stay! The hotel was clean, comfortable, and well-maintained. The staff were friendly and attentive, making the whole experience smooth and enjoyable

Reviewed on May 3, 2026

Opens in a new windowArizona Grand Resort & Spa
Crowne Plaza Phoenix Airport - PHX by IHG

Crowne Plaza Phoenix Airport - PHX by IHG

3.5 out of 5
4300 E Washington St Phoenix AZ
Fully refundable
$93 nightly
The price is $105 total per night from May 25 to May 26
$105 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free ...
Good

Reviewed on May 3, 2026

Opens in a new windowCrowne Plaza Phoenix Airport - PHX by IHG
Scottsdale Parkview Hotel

Scottsdale Parkview Hotel

3.5 out of 5
7707 E McDowell Rd Scottsdale AZ
$76 nightly
The price is $87 total per night from May 6 to May 7
$87 total
May 6 - May 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the ...
My stay at roadway inn was excellent will recommend to friends and family.

Reviewed on May 1, 2026

Opens in a new windowScottsdale Parkview Hotel
Hilton Phoenix Resort at the Peak

Hilton Phoenix Resort at the Peak

4 out of 5
7677 N 16th St Phoenix AZ
$146 nightly
The price is $165 total per night from May 27 to May 28
$165 total
May 27 - May 28
Total with taxes and fees
Free water park access, a full-service spa, and 7 outdoor pools are all featured at this resort. There's fun for all ages with a lazy river and mini golf, and ...
This hotel is under renovation not very many restaurants open or available

Reviewed on May 3, 2026

Opens in a new windowHilton Phoenix Resort at the Peak
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Mayo Clinic area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mayo Clinic to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mayo Clinic are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Mayo Clinic hotel reviews by fellow wanderers

FOUNDRE Phoenix

FOUNDRE Phoenix

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Enjoyed my stay, the place looked great and great view"
A verified traveler stayed at FOUNDRE Phoenix
FOUNDRE Phoenix

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