
Deals on vacations and trips to Defiance
Save when you book Defiance package deals
Defiance flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel
Save 100% on your flight
per person
Jul 13 - Jul 17
found 1 hour ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Moonrise Hotel
Delmar Loop
Save 100% on your flight
per person
Jul 13 - Jul 17
found 1 hour ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy a meal from the a restaurant and perks like free self parking.
Ballpark Heights Apartments By Barsala
Downtown St. Louis
Save 100% on your flight
per person
Jun 12 - Jun 16
found 21 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
A gym is featured at this aparthotel, along with free WiFi in public areas and barbecue grills. A virtual front desk are provided for your convenience.

River City Casino & Hotel
per person
Jul 13 - Jul 17
found 1 hour ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
Top Defiance hotels deals

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $130 per night
$130
includes taxes & fees
$111 per night
May 6 - May 7
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.

Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
The price is $214 per night
$214
includes taxes & fees
$183 per night
May 11 - May 12
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

Sonesta ES Suites St. Louis - Chesterfield
15431 Conway Rd, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
The price is $112 per night
$112
includes taxes & fees
$96 per night
May 12 - May 13
This hotel features a 24-hour gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. A 24-hour business center, a garden, and express check-out are also on offer.

Wingate by Wyndham St. Louis/Fenton Route 66
1100 S Highway Dr, Fenton, MO
Free Cancellation
Reserve now, pay when you stay
The price is $98 per night
$98
includes taxes & fees
$85 per night
May 6 - May 7
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express check-out. An outdoor pool and luggage storage are also provided.

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive, Fenton, MO
Free Cancellation
Reserve now, pay when you stay
The price is $103 per night
$103
includes taxes & fees
$89 per night
May 6 - May 7
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

La Quinta Inn & Suites by Wyndham St. Louis Westport
11805 Lackland Rd, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $103 per night
$103
includes taxes & fees
$89 per night
May 6 - May 7
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like self-serve breakfast and free self parking.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Busch Stadium
4.5/5(1,469 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
4/5(615 reviews)
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Zoo
4.5/5(1,212 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Photos of local treasures
Browse Defiance vacation photos for more inspiration
Top all inclusive vacation packages with airfare
Book a vacation to Defiance
Most popular
Hotels
Hotels in FentonHotels in O'FallonHotels in BallwinHotels with Hot Tubs in St. CharlesHotels in EurekaHotels in St. PetersHotels in ChesterfieldHotels in ArnoldHotels in HazelwoodHotels in BrentwoodHotels in KirkwoodHotels in St. CharlesHotels with Hot Tubs in ArnoldHotels in Granite CityHotels with Hot Tubs in ChesterfieldHotels in Maryland HeightsHotels in Lake St LouisHotels in Florissant
Cars