Book Hotels in Brussels, IL
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Top Brussels hotels

Pear Tree Inn St. Louis Airport
Everything was great
Reviewed on Dec 30, 2025

Renaissance St. Louis Airport Hotel
Clean rooms and friendly, accommodating staff.
Reviewed on Dec 24, 2025

Ameristar Casino Resort and Spa
From check-in to check-out the staff was extremely professional, friendly, and courteous. The room was fabulous. It was clean and so spacious. A sunken sitting area was an added bonus. We had a view of the river and the bridge. My expectations were definitely exceeded. The only thing that was frustrating ...
Reviewed on Dec 28, 2025

Motel 6 Hazelwood, MO
So clean and smelled so good. Staff was so friendly and helpful and just off the interstate was so convenient
Reviewed on Dec 25, 2025

Hollywood Casino & Hotel St. Louis
Everything was good. Only issue we noticed water was draining very slow both sinks and tub.
Reviewed on Dec 23, 2025

Best Western Plus The Charles Hotel
Everything was good.
Reviewed on Dec 26, 2025

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Beware of the bathtub. Iit needs help. It was slippyer. I fell. Reported it to the front desk but i believed it went in one ear and out the other
Reviewed on Dec 25, 2025

St. Louis Airport Hotel
Smells amazing and clean
Reviewed on Dec 8, 2025

La Quinta Inn & Suites by Wyndham St. Louis Westport
Wonderful staff and omelettes made for breakfast.
Reviewed on Dec 29, 2025
Brussels Hotel & Travel Guide\n
You may have realized that there are no accommodations options on Travelocity in Brussels. You don't need to stress, because you'll find 2 places to put your feet up an easy drive from Brussels.
The closest Travelocity-listed accommodation option is the Ameristar Casino Resort and Spa, Missouri, 14 miles (22 kilometers) from the downtown core of Brussels. Another handy option is the Embassy Suites St. Louis - St. Charles, situated in Missouri, 13 miles (21 kilometers) from the central area of Brussels.
You could also check out the The Green Tree Inn as well as the Staybridge Suites O'Fallon Chesterfield. The The Green Tree Inn is located only 12 miles (20 kilometers) from central Brussels. The Staybridge Suites O'Fallon Chesterfield, is located just 17 miles (28 kilometers) away. The Residence Inn by Marriott O'Fallon as well as the Sheraton Westport Plaza Hotel St. Louis are other alternative places to book accommodation in Brussels.
Researching so you can go a bit further afield? Southern Illinois has a number of things to see. If you love nature, get ready to discover Southern Illinois's rural landscapes, rolling hills and prairies. You could also venture through its farms. Visitors in this section of United States of America often enjoy rock climbing, hiking and abseiling.
25 miles (40 kilometers) away from Brussels, you will reach Alton, where visitors can enjoy Argosy Casino and Alton Square Mall. The Atrium Hotel and Conference Center and Comfort Inn are just some of the convenient lodging options in Alton. 40 miles (64 kilometers) southeast of Brussels, you'll reach Fairview Heights, which is home to the Holiday Inn St. Louis Fairview Heights and Fairfield Inn by Marriott Fairview Heights. While in Fairview Heights, it's worth visiting the Stonewolf Golf Course and St. Claire Square Mall.
If you can't stop thinking about sport and love attending local games you and your traveling partner should stop by Busch Stadium, which can be found 30 miles (50 kilometers) to the southeast of Brussels. Travelocity customers who would like the ease of booking a bed in the vicinity, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Lambert-St. Louis International Airport is a primary entry point for those flying to Brussels. It is 19 miles (30 kilometers) from the town center. If you choose to stay nearby, look into Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
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Recent Brussels hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Airport
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