Book Hotels in Brussels, IL
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Top Brussels hotels

Pear Tree Inn St. Louis Airport
"Rooms could use a little bit of an update. But this is the hotel that we usually stay out anytime we fly out. It’s very close to the airport and has free shuttle. Overall, it was a good stay."
Reviewed on Jun 10, 2026

Drury Inn & Suites St. Louis Airport
"Close to airport"
Reviewed on Jun 10, 2026

Hyatt Select St. Louis Airport
"Really appreciate Lane who was working at the front desk. He helped us as we got in very late from traveling across the country. He was extremely helpful and accommodating and patient. Huge huge shoutout to Lane for being an amazing employee. If there is any opportunity for him to get any type of ..."
Reviewed on Jun 10, 2026

Ameristar Casino Resort and Spa
"Very special treat to get to stay at this property while in St. Charles."
Reviewed on Jun 10, 2026

WoodSpring Suites St Peters-OFallon
"The location was great"
Reviewed on Jun 10, 2026

Hollywood Casino & Hotel St. Louis
"all good"
Reviewed on Jun 10, 2026

Renaissance St. Louis Airport Hotel
"Was a amazing experience such a great hotel and staff so friendly"
Reviewed on Jun 10, 2026

Motel 6 Hazelwood, MO
"Nothing the place is dirty nasty room conditions is horrible should be shut down."
Reviewed on Jun 10, 2026

La Quinta Inn & Suites by Wyndham St. Louis Westport
"Always a good breakfast and reasonably priced stay near Forest Park"
Reviewed on Jun 10, 2026
Brussels Hotel & Travel Guide\n
You may have realized that there are no accommodations options on Travelocity in Brussels. You don't need to stress, because you'll find 2 places to put your feet up an easy drive from Brussels.
The closest Travelocity-listed accommodation option is the Ameristar Casino Resort and Spa, Missouri, 14 miles (22 kilometers) from the downtown core of Brussels. Another handy option is the Embassy Suites St. Louis - St. Charles, situated in Missouri, 13 miles (21 kilometers) from the central area of Brussels.
You could also check out the The Green Tree Inn as well as the Staybridge Suites O'Fallon Chesterfield. The The Green Tree Inn is located only 12 miles (20 kilometers) from central Brussels. The Staybridge Suites O'Fallon Chesterfield, is located just 17 miles (28 kilometers) away. The Residence Inn by Marriott O'Fallon as well as the Sheraton Westport Plaza Hotel St. Louis are other alternative places to book accommodation in Brussels.
Researching so you can go a bit further afield? Southern Illinois has a number of things to see. If you love nature, get ready to discover Southern Illinois's rural landscapes, rolling hills and prairies. You could also venture through its farms. Visitors in this section of United States of America often enjoy rock climbing, hiking and abseiling.
25 miles (40 kilometers) away from Brussels, you will reach Alton, where visitors can enjoy Argosy Casino and Alton Square Mall. The Atrium Hotel and Conference Center and Comfort Inn are just some of the convenient lodging options in Alton. 40 miles (64 kilometers) southeast of Brussels, you'll reach Fairview Heights, which is home to the Holiday Inn St. Louis Fairview Heights and Fairfield Inn by Marriott Fairview Heights. While in Fairview Heights, it's worth visiting the Stonewolf Golf Course and St. Claire Square Mall.
If you can't stop thinking about sport and love attending local games you and your traveling partner should stop by Busch Stadium, which can be found 30 miles (50 kilometers) to the southeast of Brussels. Travelocity customers who would like the ease of booking a bed in the vicinity, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Lambert-St. Louis International Airport is a primary entry point for those flying to Brussels. It is 19 miles (30 kilometers) from the town center. If you choose to stay nearby, look into Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
Frequently asked questions
Recent Brussels hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Airport
"Rooms could use a little bit of an update. But this is the hotel that we usually stay out anytime we fly out. It’s very close to the airport and has free shuttle. Overall, it was a good stay."
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