Book Hotels in Brussels, IL
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Top Brussels hotels

Drury Plaza Hotel St. Louis Chesterfield
Didnt get the breakfast line to long
Reviewed on Apr 1, 2026

Pear Tree Inn St. Louis Airport
Very clean room and common areas. Parking seems safe. My only complaint was breakfast was the exact same every day-no variety at all.
Reviewed on Apr 2, 2026

Drury Inn & Suites St. Louis Airport
Friendly staff, great breakfast, clean room.
Reviewed on Apr 3, 2026

Motel 6 Hazelwood, MO
Parking is easy, air handling unit works well. My biggest frustration like with all older hotels is the number of electrcal outlets.
Reviewed on Mar 31, 2026

Hollywood Casino & Hotel St. Louis
room very clean pretty plain for a suite very spacious and comfortable
Reviewed on Apr 1, 2026

Renaissance St. Louis Airport Hotel
You could tell that the hotel was dated and there were some features that needed replaced. The faucet in the tub was extremely hard to turn on and off and the toilet paper holder was loose.
Reviewed on Apr 2, 2026

Ameristar Casino Resort and Spa
Excellent place to stay on our trip West. Rooms are amazing and spacious, great river view. Quiet, clean and comfortable. Good, safe location and much to do. Easy parking and very friendly staff. Great restaurant choices. We will be back.
Reviewed on Apr 2, 2026

Hilton St. Louis Airport
The power was out in the dining area due to storms & the staff were wonderful & had an alternative setup for breakfast.
Reviewed on Apr 1, 2026

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Legit. Old Homewood Suites now bought out
Reviewed on Apr 3, 2026
Brussels Hotel & Travel Guide\n
You may have realized that there are no accommodations options on Travelocity in Brussels. You don't need to stress, because you'll find 2 places to put your feet up an easy drive from Brussels.
The closest Travelocity-listed accommodation option is the Ameristar Casino Resort and Spa, Missouri, 14 miles (22 kilometers) from the downtown core of Brussels. Another handy option is the Embassy Suites St. Louis - St. Charles, situated in Missouri, 13 miles (21 kilometers) from the central area of Brussels.
You could also check out the The Green Tree Inn as well as the Staybridge Suites O'Fallon Chesterfield. The The Green Tree Inn is located only 12 miles (20 kilometers) from central Brussels. The Staybridge Suites O'Fallon Chesterfield, is located just 17 miles (28 kilometers) away. The Residence Inn by Marriott O'Fallon as well as the Sheraton Westport Plaza Hotel St. Louis are other alternative places to book accommodation in Brussels.
Researching so you can go a bit further afield? Southern Illinois has a number of things to see. If you love nature, get ready to discover Southern Illinois's rural landscapes, rolling hills and prairies. You could also venture through its farms. Visitors in this section of United States of America often enjoy rock climbing, hiking and abseiling.
25 miles (40 kilometers) away from Brussels, you will reach Alton, where visitors can enjoy Argosy Casino and Alton Square Mall. The Atrium Hotel and Conference Center and Comfort Inn are just some of the convenient lodging options in Alton. 40 miles (64 kilometers) southeast of Brussels, you'll reach Fairview Heights, which is home to the Holiday Inn St. Louis Fairview Heights and Fairfield Inn by Marriott Fairview Heights. While in Fairview Heights, it's worth visiting the Stonewolf Golf Course and St. Claire Square Mall.
If you can't stop thinking about sport and love attending local games you and your traveling partner should stop by Busch Stadium, which can be found 30 miles (50 kilometers) to the southeast of Brussels. Travelocity customers who would like the ease of booking a bed in the vicinity, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Lambert-St. Louis International Airport is a primary entry point for those flying to Brussels. It is 19 miles (30 kilometers) from the town center. If you choose to stay nearby, look into Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
Frequently asked questions
Recent Brussels hotel reviews by fellow wanderers

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
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