Explore top 2025 5 Star Hotels in Destin
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Top Destin 5 Star hotels
The Henderson Beach Resort & Spa
200 Henderson Resort Way, Destin, FL
Fully refundableReserve now, pay when you stay
$348 nightly
The price is $393 total per night from Nov 30 to Dec 1
$393 total
Nov 30 - Dec 1
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
9.2/10 Wonderful! (1,005 reviews)
Everything was lovely. We had such a nice time. Guest service was excellent. Housekeeping was amazing. Dining was great as well. A special thank you to the manager of Sprinkles who went above and beyond to assist us.
Reviewed on Oct 22, 2025
The Blue Pearl
9700 Grand Sandestin Blvd, Miramar Beach, FL
A full-service spa, 3 outdoor pools, and 3 hot tubs are all featured at this luxury condo resort. Enjoy the a rooftop terrace and conveniences like a picnic ...
Capitano 7 Bedroom Holiday Home by Five Star Properties
4700 Ocean Blvd, Destin, FL
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
76 Miami Street, Miramar Beach, Miramar Beach, FL
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Millenia 7 Bedroom Holiday Home by Five Star Properties
4728 Ocean Blvd, Destin, FL
Free WiFi in public areas is available at this villa. Take advantage of the free self parking.
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
4753 Ocean Blvd, Destin, FL
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
2990 Scenic Gulf Dr, Destin, FL
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Palazzo del Mar by Five Star Properties
2990 Scenic Highway 98, Destin, FL
An outdoor pool, free self parking, and barbecue grills are featured at this vacation home. WiFi in public areas is free. A terrace is also provided.
Casa Esmeralda by Five Star Properties
4624 Sunset Pointe, Destin, FL
This vacation home features an outdoor pool and a gym. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue grills are ...
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
55 Balamore Rd, Miramar Beach, Miramar Beach, FL
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Destin Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Destin to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Destin 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Destin before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Destin hotel reviews by fellow wanderers
Hampton Inn & Suites Destin
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Es gud"
A verified traveler stayed at Hampton Inn & Suites Destin
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