Explore top 2026 4 Star Hotels in Lower Matecumbe Key

Name: Condo in the Keys
Rating: 8

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Top Lower Matecumbe Key 4 Star hotels

Baker's Cay Resort Key Largo, Curio Collection by Hilton

97000 Overseas Hwy Key Largo FL

Fully refundableReserve now, pay when you stay

$286 nightly

$322 total

Sep 28 - Sep 29

Total with taxes and fees

A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...

8.6/10 Excellent! (1,182 reviews)

"Had a very relaxing time at Baker’s Cay ! Would definitely come back"

Reviewed on Sep 7, 2026

Amara Cay Resort

80001 Overseas Hwy Islamorada FL

Fully refundableReserve now, pay when you stay

$213 nightly

$239 total

Sep 24 - Sep 25

Total with taxes and fees

A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...

8.8/10 Excellent! (1,313 reviews)

"Overall the stay was just okay. The first impression was great, the women at the front desk were helpful and friendly. The following day at breakfast a server had called out resulting us having to wait an hour and a half for our food. We also weren’t served water the whole time we sat there. After ..."

Reviewed on Sep 7, 2026

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

84001 Overseas Hwy Islamorada FL

Fully refundableReserve now, pay when you stay

$248 nightly

$279 total

Sep 13 - Sep 14

Total with taxes and fees

This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL

Fully refundableReserve now, pay when you stay

$255 nightly

$286 total

Sep 13 - Sep 14

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and a water park. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...

Islander Resort

82100 Overseas Highway Islamorada FL

Fully refundableReserve now, pay when you stay

$232 nightly

$261 total

Sep 13 - Sep 14

Total with taxes and fees

A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...

La Siesta Resort & Villas

80241 Overseas Highway Islamorada FL

The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...

8.8/10 Excellent! (1,003 reviews)

"Maravillosa estancia, nos encantó todo ❤️"

Reviewed on Sep 6, 2026

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Grassy Flats Resort & Beach Club

58182 Overseas Hwy Marathon FL

$223 nightly

$251 total

Sep 20 - Sep 21

Total with taxes and fees

This smoke-free hotel features 2 outdoor pools, a hot tub, and a restaurant. Enjoy the sauna and perks like free self parking and free WiFi. There's a bar/lounge ...

9.4/10 Exceptional! (495 reviews)

"The beach isn't great, and there was a bad odor due to the sargassum. Otherwise, everything was fine. The hotel staff provides good service overall, and the cleanliness of the rooms and common areas is also good. I recommend the place; it is very welcoming, and the adults-only area is incredibly ..."

Reviewed on Sep 7, 2026

Villas At Hawks Cay Resort

61 Hawks Cay Boulevard Marathon FL

Fully refundableReserve now, pay when you stay

$434 nightly

$488 total

Sep 13 - Sep 14

Total with taxes and fees

This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...

The Islands of Islamorada

82779 Old Hwy Islamorada FL

Fully refundableReserve now, pay when you stay

$456 nightly

$512 total

Oct 1 - Oct 2

Total with taxes and fees

A marina, 2 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Spend a day at the beach kayaking, or relax with sun loungers and beach ...

Condo in the Keys

500 Burton Dr Tavernier FL

The private beach and full-service spa are among the highlights at this apartment. There's fun for all ages with a playground and an arcade/game room, and families ...

8/10 Very Good! (16 reviews)

"We had an absolutely wonderful stay and couldn’t have been happier with this condo. The location is excellent, close to everything while still offering a peaceful, relaxing atmosphere. The condo itself is beautifully decorated with a tasteful beach theme that immediately makes you feel like you’re ..."

Reviewed on Aug 1, 2026

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4 Star Hotels Lower Matecumbe Key

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Lower Matecumbe Key 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Lower Matecumbe Key will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Lower Matecumbe Key, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.