Explore top 2026 4 Star Hotels in Jeffersonville

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Top Jeffersonville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 24 to May 25
$143 total
May 24 - May 25
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,186 reviews)
My stay was good. However, need more security on the property parking garage. A man was trying to get into my car, checking the doors, my Tesla captured a video of him. Make sure to lock your car.

Reviewed on Apr 24, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from May 18 to May 19
$133 total
May 18 - May 19
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (2,008 reviews)
Great location of your visiting the Casino.

Reviewed on Apr 25, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
$249 nightly
The price is $293 total per night from May 3 to May 4
$293 total
May 3 - May 4
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,853 reviews)
We’ve stayed her multiple times. Every time it’s a 5 star. From valet parking to checking out.

Reviewed on Apr 22, 2026

Opens in a new windowOmni Louisville Hotel
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $211 total per night from May 24 to May 25
$211 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,174 reviews)
Room was very clean and the bed was so soft. Staff was very sweet from the beginning to the end.

Reviewed on Apr 25, 2026

Opens in a new windowThe Brown Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $144 total per night from May 25 to May 26
$144 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,198 reviews)
This is a beautiful hotel! They have an awesome breakfast & a hospitality from 5:30-7:00 each evening that includes food & 2 beverages each included in the price. It’s right downtown & walkable to many restaurants & Whiskey Row & other places.

Reviewed on Apr 23, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $201 total per night from May 22 to May 23
$201 total
May 22 - May 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,002 reviews)
Our room was clean, quiet, and comfortable. The staff was absolutely excellent, very helpful. We got a room with a city view, and it was beautiful. We were there on a VERY busy weekend, so some restaurant item menus were unavailable or sold out, limiting dinner options, but the food from the Porch ...

Reviewed on Apr 20, 2026

Opens in a new windowLouisville Marriott Downtown
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street Louisville KY
$133 nightly
The price is $157 total per night from May 24 to May 25
$157 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,003 reviews)
The Sway bar and restaurant were excellent. Crittendon is an excellent bartender. The lamb lollipops were amazing!

Reviewed on Apr 19, 2026

Opens in a new windowHyatt Regency Louisville
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from May 24 to May 25
$159 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,080 reviews)
The rooftop bar was beautiful on the inside! The outside portion was just ok, was hoping for a bit nicer and better service. Overall, a fine enough experience though.

Reviewed on Apr 23, 2026

Opens in a new windowHotel Genevieve part of JdV by Hyatt
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $184 total per night from May 25 to May 26
$184 total
May 25 - May 26
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,001 reviews)
Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town.

Reviewed on Apr 23, 2026

Opens in a new window21c Museum Hotel Louisville
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4 out of 5
101 West Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $206 total per night from May 25 to May 26
$206 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.6/10 Exceptional! (462 reviews)
Hotel was great. Staff amazing. We stayed in Louisville on a Sunday night and were surprised that most restaurants and bars were closed Sunday/Mondays.

Reviewed on Apr 22, 2026

Opens in a new windowHotel Distil, Autograph Collection
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4 Star Hotels Jeffersonville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Jeffersonville hotel reviews by fellow wanderers

Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

4 out of 5
Posted 3 hours ago
Travelocity Verified Review
"It was a good steak centrally located at a fair price"
A verified traveler stayed at Crowne Plaza Louisville Airport Expo Ctr by IHG
Crowne Plaza Louisville Airport Expo Ctr by IHG

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