
$271 Cheap American Airlines flights from Key West to Lexington (EYW to LEX)
Find The Best Day To Fly from Key West to Lexington
Amazing American Airlines EYW to LEX Flight Deals
The cheapest flights to Blue Grass found within the past 7 days were round trip and $271 one way. Prices and availability subject to change. Additional terms may apply.
Travelers ❤️ these 🏨 after their flight to Lexington

Courtyard Lexington Keeneland/Airport
3100 Wall St, Lexington, KY
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (752 reviews)
"This was an excellent hotel. Close to everything. Room was big and comfortable. Late night food and drinks were great and reasonable.! Staff was friendly and helpful. Would definitely stay here again."
Reviewed on Jul 14, 2025

Home2 Suites Lexington Keeneland Airport, KY
960 Midnight Pass, Lexington, KY
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
9.6/10 Exceptional! (187 reviews)
"Nice location, very walkable to near by restaurants"
Reviewed on Jul 15, 2025

Comfort Suites Keeneland
3060 Fieldstone Way, Lexington, KY
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
7.8/10 Good! (1,007 reviews)
"A bit jaded"
Reviewed on Jul 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from EYW
Top American Airlines Flight Routes from LEX
Top Flights for American Airlines originating from EYW
Domestic
- Los Angeles to Honolulu (LAX - HNL)
- New York to Montego Bay (JFK - MBJ)
- Atlanta to Las Vegas (ATL - LAS)
- Boston to Orlando (BOS - MCO)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- New York to Orlando (JFK - MCO)
- New York to Las Vegas (JFK - LAS)
- New York to San Juan (JFK - SJU)
- Philadelphia to Orlando (PHL - MCO)
International
- New York to Montego Bay (JFK - MBJ)
- Boston to Orlando (BOS - MCO)
- New York to Orlando (JFK - MCO)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Los Angeles to San Salvador (LAX - SAL)
- Chicago to Las Vegas (ORD - LAS)
- New York to Santiago (JFK - STI)
- Atlanta to Las Vegas (ATL - LAS)
- Philadelphia to San Juan (PHL - SJU)
Most Popular
Flights
- Atlanta to Miami (ATL - MIA)
- Philadelphia to Miami (PHL - MIA)
- JetBlue Airways Boston (BOS) to Orlando (MCO) flights
- JetBlue Airways Orlando (MCO) to Las Vegas (LAS) flights
- Boston to Miami (BOS - MIA)
- New York to Fort Lauderdale (JFK - FLL)
- New York to Tampa (JFK - TPA)
- Raleigh to Orlando (RDU - MCO)
- Baltimore to Orlando (BWI - MCO)
- Chicago to Orlando (ORD - MCO)
- Los Angeles to Orlando (LAX - MCO)
- Los Angeles to Miami (LAX - MIA)
- Minneapolis to Orlando (MSP - MCO)
- Dallas to Orlando (DFW - MCO)
- Detroit to Miami (DTW - MIA)
- Orlando to San Juan (MCO - SJU)
- JetBlue Airways Boston (BOS) to Fort Lauderdale (FLL) flights
- Baltimore to Miami (BWI - MIA)
- New York to Orlando (JFK - MCO)
- New York to Miami (JFK - MIA)
- Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flights
- Philadelphia to Tampa (PHL - TPA)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Orlando to Atlanta (MCO - ATL)
- Detroit to Orlando (DTW - MCO)
- Dallas to Miami (DFW - MIA)
- Hartford to Orlando (BDL - MCO)
- Cleveland to Orlando (CLE - MCO)
- Atlanta to Orlando (ATL - MCO)