Book Hotels in Winfield, MO
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Top Winfield hotels

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles MO
This vacation home features a water park and laundry facilities.
The house was incredible! Clean, cozy yet spacious and a perfect location 1/2 block from the historic district. Shops, eating and walking paths all just a few steps from our doorstep!
Reviewed on Nov 18, 2025

Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive St. Charles MO
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $133 total per night from Jan 25 to Jan 26
$133 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Great hotel
Reviewed on Jan 14, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St St. Charles MO
Fully refundable
$112 nightly
The price is $128 total per night from Jan 25 to Jan 26
$128 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests ...
Staff was friendly ,room was clean and comfortable
Reviewed on Jan 11, 2026

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Jan 25 to Jan 26
$226 total
Jan 25 - Jan 26
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
Everything was beautiful from the hotel staff to the room. It was great.
Reviewed on Jan 10, 2026

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $166 total per night from Jan 25 to Jan 26
$166 total
Jan 25 - Jan 26
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
My sister and I stayed here for a girls night out. The room is clean and the staff members are kind.
Reviewed on Jan 4, 2026

Comfort Suites St Charles - St Louis
1400 S 5th St St. Charles MO
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Jan 25 to Jan 26
$89 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Great hotel for the money
Reviewed on Jan 4, 2026

Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Jan 27 to Jan 28
$112 total
Jan 27 - Jan 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, ...
Everything was wonderful I have nothing bad to say at all.
Reviewed on Jan 12, 2026

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr Maryland Heights MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $79 total per night from Jan 27 to Jan 28
$79 total
Jan 27 - Jan 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room was nice and clean. Spacious suite.
Reviewed on Jan 14, 2026

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
Fully refundable
$58 nightly
The price is $67 total per night from Feb 2 to Feb 3
$67 total
Feb 2 - Feb 3
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
The room was spotless and clean.
Reviewed on Jan 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Winfield with star-rating
Check Winfield Hotels by Star Rating

3 Star Hotels
44 properties
Frequently asked questions
Recent Winfield hotel reviews by fellow wanderers

Sleep Inn & Suites O'Fallon MO - Technology Drive
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Nice staff, room was adequate "
A verified traveler from sioux falls stayed at Sleep Inn & Suites O'Fallon MO - Technology Drive
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