Cheap Flights to Southeast Missouri from $29

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How Much Does it Cost To Fly To Southeast Missouri?

The cheapest prices found with in the last 7 days for return flights were $58 and $29 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply

Sat, Jan 24 - Sat, Jan 31
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$58 Roundtrip, found 3 hours ago
$58
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Sat, Jan 24 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Jan 31, priced at $58 found 3 hours ago
Sat, Feb 21 - Sat, Feb 28
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$130 Roundtrip, found 23 hours ago
$130
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Sat, Feb 21 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Sat, Feb 28, priced at $130 found 23 hours ago
OriginDestinationTravel DatesFlights From*
MSYSt. LouisFebruary 21 to February 28$128
BWISt. LouisJanuary 31 to February 7$129
DCASt. LouisJanuary 31 to February 2$147
SATSt. LouisFebruary 21 to February 23$147
MSPSt. LouisJanuary 26 to January 28$147
LAXSt. LouisJanuary 21 to January 28$151
CMHSt. LouisJanuary 8 to January 14$174
EWRSt. LouisMarch 3 to March 9$174
MCISt. LouisJanuary 12 to January 14$175
LAXScott CityMarch 28 to April 1$504
MSPMarionJanuary 2 to January 3$539
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
MSYSt. LouisDecember 28 to January 1$274
LAXSt. LouisDecember 28 to January 8$322
BWISt. LouisDecember 26 to December 28$413
SATSt. LouisDecember 28 to December 31$425
EWRSt. LouisDecember 28 to January 1$437
DCASt. LouisDecember 28 to January 1$510
MCISt. LouisDecember 27 to January 1$515
MSPSt. LouisDecember 27 to December 31$622
MCIScott CityDecember 26 to December 29$943
*Prices include taxes and fees

Southeast Missouri Flight Information

Traveling to
Southeast Missouri
Lowest Price
$58
Number of Airlines Serving
Airlines Serving
Frontier Airlines, Contour Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Southeast Missouri Accommodation Deals

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
$76 nightly
The price is $80 total per night from Dec 25 to Dec 26
$80 total
Dec 25 - Dec 26
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,002 reviews)
Staff was amazing and super nice. Room was very clean.

Reviewed on Dec 11, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Dec 29 to Dec 30
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
This is our go to when we visit relatives

Reviewed on Dec 5, 2025

Opens in a new windowPear Tree Inn Sikeston
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr Farmington MO
$53 nightly
The price is $60 total per night from Dec 31 to Jan 1
$60 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (612 reviews)
The room was excellent and the staff was extremely nice

Reviewed on Nov 25, 2025

Opens in a new windowSuper 8 by Wyndham Farmington
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Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z Pevely MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (831 reviews)
Awesome

Reviewed on Nov 11, 2025

Get rates
Opens in a new windowSuper 8 by Wyndham Pevely
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z Pevely MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (831 reviews)
Awesome

Reviewed on Nov 11, 2025

Get rates
Opens in a new windowSuper 8 by Wyndham Pevely
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
$76 nightly
The price is $80 total per night from Dec 25 to Dec 26
$80 total
Dec 25 - Dec 26
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,002 reviews)
Staff was amazing and super nice. Room was very clean.

Reviewed on Dec 11, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night from Dec 28 to Dec 29
$72 total
Dec 28 - Dec 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Super spacious room and delightful staff. Recommended to ALL

Reviewed on Dec 20, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
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Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (172 reviews)
Great place! It was exactly as advertised. We were so close to shops and restaurants. We will definitely be back!

Reviewed on Oct 12, 2025

Get rates
Opens in a new windowHistorical 'Kage House' Short Term Rental located in "Old Town Cape"
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southeast Missouri

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night from Dec 29 to Dec 30
$103 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
This our favorite place to stop for a good night sleep.

Reviewed on Dec 22, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Dec 29 to Dec 30
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
This is our go to when we visit relatives

Reviewed on Dec 5, 2025

Opens in a new windowPear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
$76 nightly
The price is $86 total per night from Dec 29 to Dec 30
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
Great stay, everything was clean and comfortable.

Reviewed on Dec 20, 2025

Opens in a new windowBest Western Plus Sikeston
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Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Dec 29 to Dec 30
$102 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (999 reviews)
The staff was all friendly clean rooms and really enjoyed our stay

Reviewed on Dec 13, 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Southeast Missouri Flight and Hotel Packages

Southeast Missouri flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $640, price is now $482 per person
$482
per person
Jan 30 - Feb 1
found 1 day ago
Roundtrip flight included
Washington (DCA) to St. Louis (STL)
The Cheshire

The Cheshire

4 out of 5
Price was $617, price is now $494 per person
$494
per person
Jan 29 - Feb 1
found 2 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to St. Louis (STL)
Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Price was $641, price is now $520 per person
$520
per person
Jan 29 - Feb 1
found 2 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to St. Louis (STL)
Don't see what you're looking for?
See all available trips from Washington to Southeast Missouri
View all trips

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

How much is the cheapest flight to Southeast Missouri?
A roundtrip flight to Southeast Missouri cost as little as $58 over the last seven days. Once you've chosen your travel dates, we'll help you find an amazing deal. This price was available on Travelocity for flights to Southeast Missouri departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southeast Missouri?
Be sure to leave January empty in your calendar, because it's the most affordable month to travel to Southeast Missouri. That's based on Travelocity's direct flight demand from January to December last year. With the cash you save, you can go on a spending spree, go for a fancy dinner or whatever makes you happy.
How can I check my flight status to Southeast Missouri?
Make the most of Travelocity's handy portal, Trips. You'll find just about everything related to your flight to Southeast Missouri here, including details about flight status, gate numbers and more. Look for Trips at the top of the Travelocity homepage. Create your free account and get the answers you need. Or you can access your itinerary while you're on the go and get real-time travel updates through the Travelocity app. You'll find all your itineraries in one place, making it a cinch to share details with any members of your family flying with you.
How do I find the best deals on flights to Southeast Missouri?
Being flexible with your dates is one of the best ways to snag an awesome deal. Travelocity makes it a cinch to find your perfect fare through the "Flexible dates" feature. First, search for your Southeast Missouri flight, then compare prices for surrounding dates by hitting the Flexible dates box above. Booking in advance and avoiding peak travel periods are other steps you can take. In the last seven days, the lowest price for a return flight to Southeast Missouri was $58. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southeast Missouri with Travelocity?
If you're looking for cheap flights to Southeast Missouri, you'll discover some tempting deals with Travelocity. From cheap family flights with low-cost airlines to flexible tickets, we can help you. Enjoy a worry-free trip with our 24/7 customer support, Price Match Guarantee and free cancellations with most hotels. Start packing your bags and get ready to jump on a plane to this interesting destination.
How much is a flight to Southeast Missouri on average?
Airfares for roundtrip flights to Southeast Missouri were priced between $58 and $943 in the last seven days. The minute you spot a good deal, snap it up and get ready for your dream getaway with Travelocity. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What can I expect on a flight to Southeast Missouri?
Factors like who you're flying with and where you're departing from will mostly determine what you'll be offered on your trip. Chances are you'll find all kinds of flights to Southeast Missouri, from cheap flights for family vacations to premium fares. Warm meals, entertainment and games for the little ones are usually what most airlines offer on long-haul flights.

Plane Tickets To Southeast Missouri

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.