Book Hotels in South Carolina Midlands, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jun 28 to Jun 29
$109 total
Jun 28 - Jun 29
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"Nice hotel, but our room had bed bugs. Told the reception in the morning, gave her the live bed buv in a zip lock, and she said they were going to close the room off for service Good breakfast, overall nice hotel w free parking. But needs a fumigation. Maybe just bad luck for us left over by previous ..."
Reviewed on Jun 19, 2026

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jul 5 to Jul 6
$96 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"I really enjoyed my stay at this hotel. The staff was kind and friendly the property was clean, the rooms was fresh. I can smell clean. It was right to have a little restaurant in the hotel so if you didn't want to go out food was available for you. I recommend this hotel a lot."
Reviewed on Jun 19, 2026

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Jun 28 to Jun 29
$100 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"Clean room and friendly staff. Would definitely recommend. Great value!"
Reviewed on Jun 20, 2026

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive Columbia SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Jun 28 to Jun 29
$105 total
Jun 28 - Jun 29
Total with taxes and fees
This smoke-free hotel includes 20 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
"Rooms are clean staff helpful"
Reviewed on Jun 20, 2026

Clarion Pointe Rock Hill Near University
1106 N. Anderson Road Rock Hill SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Jun 21 to Jun 22
$88 total
Jun 21 - Jun 22
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public ...
"The lady at the front was very nice and helpful. I didn’t like that it didn’t have an elevator, but she put us on the bottom floor. The pool was not operable. Above all I would stay again."
Reviewed on Jun 19, 2026

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Jun 21 to Jun 22
$99 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Everything was nice but as with many hotels the walls are very thin and the noise carries, hard to get any sleep on a weekend hearing doors opening and closing throughout the night. But the place was clean and a very friendly staff !!"
Reviewed on Jun 18, 2026

Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Jun 28 to Jun 29
$132 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Coean and friendly staff"
Reviewed on Jun 19, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Jun 21 to Jun 22
$92 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"Building was not well maintained… under construction"
Reviewed on Jun 19, 2026

Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jul 2 to Jul 3
$123 total
Jul 2 - Jul 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels

Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$56 nightly
The price is $62 total per night from Jul 14 to Jul 15
$62 total
Jul 14 - Jul 15
Total with taxes and fees
6/10 (918 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating

4 Star Hotels
12 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers

Park Inn by Radisson Florence, SC
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Clean room and friendly staff. Would definitely recommend. Great value!"
A verified traveler stayed at Park Inn by Radisson Florence, SC
Explore More Ways to Travel with Travelocity
- Hotels near Palmetto Health Heart Hospital
- Hotels near University of South Carolina
- Adults Only Resorts & in Lake Carolina
- Romantic Getaways & Hotels in Lake Carolina
- Lake Carolina Hotels
- Hotels near Oak Hills Golf Club
- Hotels near Hampton-Preston Mansion and Gardens
- Hotels near Segra Park
- Hotels with Suites in Shandon
- Shandon Hotels
- Beach Resorts & in Waverly
- Hotels with Suites in Waverly
- Waverly Hotels
- Hotels near Hilton Field
- Hotels near Village at Sandhill Mall
- Hotels near Palmetto Health Richland Hospital
- 4 Star Hotels in Elgin
- Apartments in Elgin
- B&B in Elgin
- Cabins in Elgin
- Condos in Elgin
- Extended Stay Hotels in Elgin
- Guest Houses in Elgin
- Elgin Hotels
- Motels in Elgin
- Vacation Homes in Elgin
- Apartments in Woodfield
- B&B in Woodfield
- Condos in Woodfield
- Cottages in Woodfield
- Woodfield Hotels
- Motels in Woodfield
- Downtown Columbia Hotels
- All Inclusive Resorts & in South Carolina
- Ski Resorts and in South Carolina
- Cabins in South Carolina
- Hotels near Sesquicentennial State Park
- Hotels near Palmetto Falls Water Park
- B&B in Dentsville
- Hotels with Bar in Dentsville
- Luxury Hotels in Dentsville
- Pet Friendly Hotels in Dentsville
- Dentsville Hotels
- Vacation Homes in Dentsville
- 4 Star Hotels in Blythewood
- 5 Star Hotels in Blythewood
- Apartments in Blythewood
- B&B in Blythewood
- Cabins in Blythewood
- Cottages in Blythewood
- Extended Stay Hotels in Blythewood
- Guest Houses in Blythewood
- Cheap Hotels in Blythewood
- Hotels with Hot Tubs in Blythewood
- Pet Friendly Hotels in Blythewood
- Spa Resorts & in Blythewood
- Hotel Wedding Venues Hotels in Blythewood
- Blythewood Hotels
- Motels in Blythewood
- Vacation Homes in Blythewood
- Extended Stay Hotels in Columbia
- Hotels with Hot Tubs in Columbia
- Luxury Hotels in Columbia
- Columbia Hotels
- Motels in Columbia
- Hotels near William Jennings Bryan Dorn Veterans Affairs Medical Center
- Old Shandon Hotels
- Hotels near Township Auditorium
- University Hill Hotels
- Hotels near Charlie W. Johnson Stadium
- Hotels near Allen University
- Hotels near Fort Jackson
- Apartments in Royal Pines Estates
- B&B in Royal Pines Estates
- Condos in Royal Pines Estates
- Guest Houses in Royal Pines Estates
- Hotels near Benedict College
- Hotels near Columbia Place Mall
- Hotels near Polo Road Ball Park
- Killian Hotels













