South Carolina Midlands , SC Pet Friendly Hotels

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Top South Carolina Midlands Pet Friendly Hotels

Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jul 19 to Jul 20
$109 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
9.2/10 Wonderful! (1,004 reviews)
"Very nice hotel. Comfortable bed and clean room. Staff very courteous."

Reviewed on Jul 2, 2026

Opens in a new windowHampton Inn Columbia I-26/Harbison Blvd.
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Jul 6 to Jul 7
$100 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
8.6/10 Excellent! (223 reviews)
"This place was perfect too bad we were only staying for one night. We loved it. Definitely staying there again."

Reviewed on Jul 4, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jul 6 to Jul 7
$95 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
8.2/10 Very Good! (1,009 reviews)
"Great parking and breakfast"

Reviewed on Jul 4, 2026

Opens in a new windowLa Quinta Inn by Wyndham Columbia SE / Fort Jackson
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd Santee SC
Fully refundable
$100 nightly
The price is $111 total per night from Aug 2 to Aug 3
$111 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,000 reviews)
"Beds & pillows are very comfortable. Amenities needs some upgrading....I brewed a keurig cup coffee & grinds were in the cup. Toilet to upgrade & shower curtain too small. But very clean!"

Reviewed on May 30, 2026

Opens in a new windowHoliday Inn Santee by IHG
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Jul 13 to Jul 14
$109 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
7.8/10 Good! (1,560 reviews)
"No, what I expected from La Quinta. I feel like they under staff, because the maintenance and cleanliness is poor."

Reviewed on Jul 4, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

731 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Jul 26 to Jul 27
$106 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
7.8/10 Good! (1,001 reviews)
"We checked in at 9:00 pm - pool closed room never cooled down- especially the front half of the room where sofa beds is located. left at 6:30 am room was not that cleaned - needs carpet cleaned; all mattress needs to be replaced including sofa bed. Hotel is dark and needs to be cleaned including ..."

Reviewed on Jun 23, 2026

Opens in a new windowSpark by Hilton Orangeburg
Best Western Inn

Best Western Inn

1808 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $80 total per night from Jul 6 to Jul 7
$80 total
Jul 6 - Jul 7
Total with taxes and fees
A seasonal outdoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public ...
7.8/10 Good! (1,002 reviews)
"Clean room,easy check in,great hot breakfast with eggs, sausage, gravy, biscuits, waffles, pastries and cereal"

Reviewed on Jul 4, 2026

Opens in a new windowBest Western Inn
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2690 David H McLeod Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Aug 2 to Aug 3
$63 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (1,001 reviews)
"My bed was sunken in, the room stunk and I lost my money because I made a mistake and booked 2 rooms on the same date"

Reviewed on Jul 4, 2026

Opens in a new windowRed Roof Inn Florence - Civic Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Carolina Midlands hotels essential information

Accommodation
3,295 hotels
Lowest Price
$63
Highest Price
$111
Popular hotels
La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Spark by Hilton Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Best Western Inn

Recent South Carolina Midlands hotel reviews by fellow wanderers

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