Explore top 2026 4 Star Hotels in South Carolina Midlands

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Top South Carolina Midlands 4 Star hotels

Graduate by Hilton Columbia SC

1619 Pendleton Street Columbia SC

$139 nightly

$155 total

Feb 2 - Feb 3

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...

9.2/10 Wonderful! (1,002 reviews)

Perfect place to stay when visiting USC

Reviewed on Jan 21, 2026

Doubletree by Hilton Columbia, SC

2100 Bush River Road Columbia SC

Fully refundableReserve now, pay when you stay

$125 nightly

$135 total

Feb 2 - Feb 3

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

7.8/10 Good! (999 reviews)

Just that the hotel staff were very courteous and provided everything I asked for.

Reviewed on Jan 5, 2026

Wyndham Vacation Resorts Lake Marion

401 Bass Drive Santee SC

An outdoor pool is available at this vacation home. Take advantage of the free self parking.

9.2/10 Wonderful! (22 reviews)

The room was spacious and very clean. The front desk person was friendly and they did try to sell my fiance some things, but he wasn't interested. Once we kindly said no they understood and wasn't being pushy which we greatly appreciated. My family and I will stay here each time. My fiance and I ...

Reviewed on Jan 9, 2026

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Burrell and Flynn's Farm

3057 Charleston Hwy Aiken SC

$258 nightly

$290 total

Feb 8 - Feb 9

Total with taxes and fees

An outdoor pool, free self parking, and barbecue grills are featured at this bed & breakfast. Guests will appreciate free perks like cooked-to-order breakfast ...

10/10 Exceptional! (4 reviews)

Thoroughly enjoyed our stay with Beth at Burrell and Flynn’s Farm. Beautiful home and comfortable room. Lots of love and thought put into anticipating guests needs from the welcome reception to the details in each room and bathroom. Breakfast was a highlight and got us set for our day. Very well ...

Reviewed on Oct 31, 2025

Rosewood Manor House B&B

900 North Main Street Marion SC

A restaurant and a bar/lounge are featured at this bed & breakfast. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...

I could fill my review with descriptions of this lavish property but am sure you will read dozens of illustrations of this stately piece of landmark history, so i would rather mention some of our personal interactions with inn keepers Gary and John. I was in town for a family wedding with my husband. ...

Reviewed on Jan 3, 2019

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Soda City Retreat

208 Council Loop Columbia SC

Free WiFi in public areas is available at this vacation home.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels South Carolina Midlands

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South Carolina Midlands 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South Carolina Midlands will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South Carolina Midlands, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.