Book Hotels in South Carolina Midlands, SC

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Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street, Building 2, Columbia, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Jul 20 to Jul 21
$113 total
Jul 20 - Jul 21
Total includes taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"Scrims for windows with no functioning light-blocking shades or curtains is pretty miserable for east-facing room where you get full sun at dawn."

Reviewed on Jul 12, 2025

Tru By Hilton Columbia Downtown
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jul 27 to Jul 28
$123 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"one of the nicest comfort inns ive ever been to… bed was super comfortable"

Reviewed on Jul 11, 2025

Comfort Inn & Suites
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jul 20 to Jul 21
$111 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Nice
"Very good service"

Reviewed on Jul 10, 2025

Park Inn by Radisson Florence, SC
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jul 27 to Jul 28
$94 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This was a very attractive and clean facility and with a lovely staff."

Reviewed on Jul 10, 2025

Hilton Garden Inn Columbia/Harbison
Clarion Pointe Near University

Clarion Pointe Near University

2.5 out of 5
1106 N. Anderson Road, Rock Hill, SC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Aug 10 to Aug 11
$84 total
Aug 10 - Aug 11
Total includes taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public ...
"Staff was friendly. Motel was very clean. Very pet friendly. Great stay."

Reviewed on Jul 10, 2025

Clarion Pointe Near University
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 14 to Jul 15
$79 total
Jul 14 - Jul 15
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean, quiet and affordable
"Short one night stay. Room was clean and quiet."

Reviewed on Jul 10, 2025

Howard Johnson by Wyndham Florence
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jul 20 to Jul 21
$95 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Guests will appreciate freebies like buffet breakfast and free self parking. A garden, a grocery/convenience ...
"Definitely a most stay on my next trip to SC"

Reviewed on Jul 7, 2025

Wyndham Garden Columbia/Ft. Jackson
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jul 20 to Jul 21
$94 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
"Awesome experience all around. Billy was extremely helpful and went above and beyond"

Reviewed on Jul 9, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Baymont by Wyndham Columbia Fort Jackson

Baymont by Wyndham Columbia Fort Jackson

2.5 out of 5
240 E Exchange Blvd, Columbia, SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Jul 20 to Jul 21
$74 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
"Family friendly with awesome staff!"

Reviewed on Jul 2, 2025

Baymont by Wyndham Columbia Fort Jackson
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South Carolina Midlands hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South Carolina Midlands hotel reviews by fellow wanderers

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