Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown
400 Gervais Street, Building 2, Columbia, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Jul 20 to Jul 21
$113 total
Jul 20 - Jul 21
Total includes taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"Scrims for windows with no functioning light-blocking shades or curtains is pretty miserable for east-facing room where you get full sun at dawn."
Reviewed on Jul 12, 2025

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jul 27 to Jul 28
$123 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"one of the nicest comfort inns ive ever been to… bed was super comfortable"
Reviewed on Jul 11, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jul 20 to Jul 21
$111 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Nice
"Very good service"
Reviewed on Jul 10, 2025

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jul 27 to Jul 28
$94 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This was a very attractive and clean facility and with a lovely staff."
Reviewed on Jul 10, 2025

Clarion Pointe Near University
1106 N. Anderson Road, Rock Hill, SC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Aug 10 to Aug 11
$84 total
Aug 10 - Aug 11
Total includes taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public ...
"Staff was friendly. Motel was very clean. Very pet friendly. Great stay."
Reviewed on Jul 10, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 14 to Jul 15
$79 total
Jul 14 - Jul 15
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean, quiet and affordable
"Short one night stay. Room was clean and quiet."
Reviewed on Jul 10, 2025

Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jul 20 to Jul 21
$95 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Guests will appreciate freebies like buffet breakfast and free self parking. A garden, a grocery/convenience ...
"Definitely a most stay on my next trip to SC"
Reviewed on Jul 7, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jul 20 to Jul 21
$94 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
"Awesome experience all around. Billy was extremely helpful and went above and beyond"
Reviewed on Jul 9, 2025

Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd, Columbia, SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Jul 20 to Jul 21
$74 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
"Family friendly with awesome staff!"
Reviewed on Jul 2, 2025
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels

Econo Lodge
914 Riverview Rd, Rock Hill, SC
$54 nightly
The price is $60 total per night from Aug 10 to Aug 11
$60 total
Aug 10 - Aug 11
Total includes taxes and fees
6/10 (818 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating

4 Star Hotels
5 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Fronts desk was very friendly. Rooms were very clean and quiet. Wou definitely stay here again "
A verified traveler stayed at La Quinta Inn by Wyndham Columbia NE/Fort Jackson
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