Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels
Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $164 total per night from Mar 15 to Mar 16
$164 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...
Beautifully decorated, very clean hotel. Wonderful staff and very convenient to campus.
Reviewed on Mar 2, 2026
Cambria Hotel Columbia Downtown The Vista
1000 Lady Street Columbia SC
$119 nightly
The price is $133 total per night from Mar 15 to Mar 16
$133 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
This is a great property. It is within walking distance to shops, restaurants and just about anything you may want to do.
Reviewed on Mar 2, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $110 total per night from Mar 8 to Mar 9
$110 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Clean room, good breakfast...very nice overnight stay.
Reviewed on Mar 2, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Mar 22 to Mar 23
$105 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The Front Desk ladies were very accommodating. Rooms were dropping late, and those ladies held it together and made sure all guests were taken care. It was a hectic weekend and those ladies showed how to be TRUE LEADERs. I thank them for accommodating myself and my family.
Reviewed on Mar 2, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$86 nightly
The price is $96 total per night from Mar 8 to Mar 9
$96 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Did not use it
Reviewed on Mar 2, 2026
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct Columbia SC
Fully refundable
$114 nightly
The price is $127 total per night from Mar 22 to Mar 23
$127 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Always a great stay and good breakfast.
Reviewed on Mar 2, 2026
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Mar 23 to Mar 24
$91 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
Clean room with friendly and helpful staff.
Reviewed on Mar 2, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Apr 3 to Apr 4
$91 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Our room was clean.
Reviewed on Mar 2, 2026
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Mar 8 to Mar 9
$99 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
Clean, quiet and pleasant staff
Reviewed on Feb 26, 2026
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$48 nightly
The price is $54 total per night from Mar 20 to Mar 21
$54 total
Mar 20 - Mar 21
Total with taxes and fees
6/10 (882 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
6 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Tru By Hilton Columbia Downtown
5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Great location in downtown Columbia! Convenient parking and nice amenities."
A verified traveler stayed at Tru By Hilton Columbia Downtown
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