Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels
Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $152 total per night from May 2 to May 3
$152 total
May 2 - May 3
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...
Room not vacuumed. Rude restaurant manager. Beautiful hotel; convenient parking. Instant decaf (only) coffee and electric tea kettle in room!!!!
Reviewed on Apr 15, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$85 nightly
The price is $95 total per night from May 17 to May 18
$95 total
May 17 - May 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Quick location off the interstate. Clean with attentive staff. Beds and linens all clean and comfortable. Nice breakfast provided. Lovely simple hotel. Facilities are well kept. I'd come back!
Reviewed on Apr 16, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$100 nightly
The price is $112 total per night from May 17 to May 18
$112 total
May 17 - May 18
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
I love this place I would stay again
Reviewed on Apr 16, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from May 3 to May 4
$87 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean
Reviewed on Apr 16, 2026
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 26 to Apr 27
$75 total
Apr 26 - Apr 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Didn't do breakfast there.
Reviewed on Apr 16, 2026
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from May 10 to May 11
$91 total
May 10 - May 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
Clean room
Reviewed on Apr 16, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $98 total per night from May 3 to May 4
$98 total
May 3 - May 4
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Parking was easy, area and room was clean. Staff were helpful and nice! Breakfast was good. Would definitely come back.
Reviewed on Apr 14, 2026
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from May 3 to May 4
$99 total
May 3 - May 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
The staff was really attentive and sweet. We had trouble with our door and she assisted and we had trouble with our tv and she helped. The lobby is beautiful and the breakfast and 24 hour coffee was great. It appears that the owner tried to make a fun outdoor games area; however, it was right outside ...
Reviewed on Apr 15, 2026
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
Fully refundable
$83 nightly
The price is $93 total per night from Apr 19 to Apr 20
$93 total
Apr 19 - Apr 20
Total with taxes and fees
A full-service spa and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
The room was completely dirty when we went to the front desk, (nmitch) brought us cleaning supplies so that we could clean the room ourselves and said that if we kept bothering her she would call the police to have us removed from the hotel, since she had many people to check in.
Reviewed on Apr 15, 2026
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$47 nightly
The price is $52 total per night from Apr 30 to May 1
$52 total
Apr 30 - May 1
Total with taxes and fees
6/10 (901 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
13 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Sleep Inn Columbia
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Clean room "
A verified traveler stayed at Sleep Inn Columbia
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