Book Hotels in South Carolina Midlands, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top South Carolina Midlands hotels

Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
$133 nightly
The price is $149 total per night from Apr 13 to Apr 14
$149 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...
Awesome property close to campus. Everything was fabulous. Would have liked to know more of the history of the building - staff did not know
Reviewed on Mar 17, 2026

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$105 nightly
The price is $117 total per night from Mar 18 to Mar 19
$117 total
Mar 18 - Mar 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
I would stay again. The floor above walking was a bit obnoxious. But I still had a good night sleep. Staff was pleasant.
Reviewed on Mar 17, 2026

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
$96 nightly
The price is $108 total per night from Apr 12 to Apr 13
$108 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was wonderful! It was a long day of travel, and we checked in late, but the staff was so kind and accommodating, the facility was fresh and inviting and the rooms were extremely comfy with generous space and amenities. Would absolutely recommend (we will be back later this week even, on ...
Reviewed on Mar 17, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct Columbia SC
Fully refundable
$114 nightly
The price is $127 total per night from Mar 22 to Mar 23
$127 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Everyone was beyond friendly and couldn't ask for a better experience million times recommend
Reviewed on Mar 17, 2026

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 1 to Apr 2
$75 total
Apr 1 - Apr 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
We had a great stay.The continental breakfast could have been a little more robust, but for the price for the room it was great and the rooms were clean and everything was wonderful.
Reviewed on Mar 16, 2026

Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Apr 12 to Apr 13
$91 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
The toilet in our room wouldn't flush even after they brought a plunger. The shower is hot and relaxing. The bed was very comfortable. Not too many good channels on the TV. We stayed 3 nights. Very quiet and clean. The room could use some updating. The bathroom door wouldn't go all the way inside ...
Reviewed on Mar 16, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
$85 nightly
The price is $95 total per night from Mar 29 to Mar 30
$95 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
The room was clean breakfast was good, usual hotel fare but everything was hot and area clean. Parking lot
Reviewed on Mar 17, 2026

Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Mar 29 to Mar 30
$99 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
Breakfast was very good and fresh.
Reviewed on Mar 15, 2026

Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive Columbia SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $58 total per night from Apr 4 to Apr 5
$58 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features an outdoor pool and a gym. Families will appreciate the arcade/game room and barbecue grills. There's no skimping on freebies - guests receive ...
The management is extraordinary and extremely professional! A peaceful environment and relaxing atmosphere. Recommend highly!
Reviewed on Mar 17, 2026
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels

Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$48 nightly
The price is $53 total per night from Apr 17 to Apr 18
$53 total
Apr 17 - Apr 18
Total with taxes and fees
6/10 (888 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating

4 Star Hotels
6 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers

Graduate by Hilton Columbia SC
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Awesome property close to campus. Everything was fabulous. Would have liked to know more of the history of the building - staff did not know"
A verified traveler stayed at Graduate by Hilton Columbia SC
Explore More Ways to Travel with Travelocity
- Hotels near Palmetto Health Heart Hospital
- Hotels near University of South Carolina
- Adults Only Resorts & in Lake Carolina
- Romantic Getaways & Hotels in Lake Carolina
- Lake Carolina Hotels
- Hotels near Oak Hills Golf Club
- Hotels near Hampton-Preston Mansion and Gardens
- Hotels near Segra Park
- Hotels with Suites in Shandon
- Shandon Hotels
- Beach Resorts & in Waverly
- Hotels with Suites in Waverly
- Waverly Hotels
- Hotels near Hilton Field
- Hotels near Village at Sandhill Mall
- Hotels near Palmetto Health Richland Hospital
- 4 Star Hotels in Elgin
- Apartments in Elgin
- B&B in Elgin
- Cabins in Elgin
- Condos in Elgin
- Extended Stay Hotels in Elgin
- Guest Houses in Elgin
- Elgin Hotels
- Motels in Elgin
- Vacation Homes in Elgin
- Apartments in Woodfield
- B&B in Woodfield
- Condos in Woodfield
- Cottages in Woodfield
- Woodfield Hotels
- Motels in Woodfield
- Downtown Columbia Hotels
- All Inclusive Resorts & in South Carolina
- Ski Resorts and in South Carolina
- Cabins in South Carolina
- Hotels near Sesquicentennial State Park
- Hotels near Palmetto Falls Water Park
- B&B in Dentsville
- Hotels with Bar in Dentsville
- Luxury Hotels in Dentsville
- Pet Friendly Hotels in Dentsville
- Dentsville Hotels
- Vacation Homes in Dentsville
- 4 Star Hotels in Blythewood
- 5 Star Hotels in Blythewood
- Apartments in Blythewood
- B&B in Blythewood
- Cabins in Blythewood
- Cottages in Blythewood
- Extended Stay Hotels in Blythewood
- Guest Houses in Blythewood
- Cheap Hotels in Blythewood
- Hotels with Hot Tubs in Blythewood
- Pet Friendly Hotels in Blythewood
- Spa Resorts & in Blythewood
- Hotel Wedding Venues Hotels in Blythewood
- Blythewood Hotels
- Motels in Blythewood
- Vacation Homes in Blythewood
- Extended Stay Hotels in Columbia
- Hotels with Hot Tubs in Columbia
- Luxury Hotels in Columbia
- Columbia Hotels
- Motels in Columbia
- Hotels near William Jennings Bryan Dorn Veterans Affairs Medical Center
- Old Shandon Hotels
- Hotels near Township Auditorium
- University Hill Hotels
- Hotels near Charlie W. Johnson Stadium
- Hotels near Allen University
- Hotels near Fort Jackson
- Apartments in Royal Pines Estates
- B&B in Royal Pines Estates
- Condos in Royal Pines Estates
- Guest Houses in Royal Pines Estates
- Hotels near Benedict College
- Hotels near Columbia Place Mall
- Hotels near Polo Road Ball Park
- Killian Hotels













