Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$71 nightly
The price is $80 total per night from Sep 7 to Sep 8
$80 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"I cannot say enough about how helpful the woman at the front desk was! We had to cancel our stay at the last moment and she went above and beyond to help us, working with Expedia to credit us. She did not have to but she did! She was so kind and gracious and I would definitely book here again- great ..."
Reviewed on Aug 6, 2026
Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Aug 21 to Aug 22
$132 total
Aug 21 - Aug 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
"The room was clean and pretty just like the pictures. Great location downtown and was near everything. Staff was nice and very helpful."
Reviewed on Aug 7, 2026
Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Aug 9 to Aug 10
$132 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"We were very impressed with the room. The place was super clean. The breakfast was wonderful, with many different options. The only downside was the parking lot wasn’t very big, but they had a public parking lot just a block away so it wasn’t too bad. I would highly recommend this hotel to anyone ..."
Reviewed on Aug 3, 2026
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Aug 11 to Aug 12
$73 total
Aug 11 - Aug 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Room design and cleanliness was excellent and provided a good night’s sleep. The breakfast options provided something for all and well stocked."
Reviewed on Aug 6, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Aug 22 to Aug 23
$106 total
Aug 22 - Aug 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"Stay was great!"
Reviewed on Aug 6, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Aug 16 to Aug 17
$96 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $93 total per night from Sep 7 to Sep 8
$93 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Sep 6 to Sep 7
$109 total
Sep 6 - Sep 7
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Aug 27 to Aug 28
$91 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$47 nightly
The price is $53 total per night from Aug 27 to Aug 28
$53 total
Aug 27 - Aug 28
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
12 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Courtyard by Marriott Columbia Downtown at USC
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"The room was clean and pretty just like the pictures. Great location downtown and was near everything. Staff was nice and very helpful."
A verified traveler stayed at Courtyard by Marriott Columbia Downtown at USC
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