Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"Nice room. Great staff."
Reviewed on Sep 11, 2026
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Oct 1 to Oct 2
$91 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
"Ok place for a one night stay."
Reviewed on Sep 10, 2026
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Sep 20 to Sep 21
$87 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
"This Wyndham Garden doesn’t represent the Brand!!!"
Reviewed on Sep 10, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Oct 11 to Oct 12
$96 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $114 total per night from Sep 13 to Sep 14
$114 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Sep 27 to Sep 28
$109 total
Sep 27 - Sep 28
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $142 total per night from Sep 27 to Sep 28
$142 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
Fully refundable
$77 nightly
The price is $87 total per night from Sep 20 to Sep 21
$87 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$49 nightly
The price is $56 total per night from Oct 10 to Oct 11
$56 total
Oct 10 - Oct 11
Total with taxes and fees
6.2/10 (945 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
14 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Park Inn by Radisson Florence, SC
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Nice room. Great staff."
A verified traveler stayed at Park Inn by Radisson Florence, SC
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