Book Hotels in South Carolina Midlands, SC

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Jun 26 - Jun 28
Next weekend
Jul 3 - Jul 5

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jul 5 to Jul 6
$109 total
Jul 5 - Jul 6
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"The staff was very friendly and took great care of us"

Reviewed on Jun 25, 2026

Opens in a new windowTru By Hilton Columbia Downtown
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street Columbia SC
Fully refundable
$116 nightly
The price is $130 total per night from Jul 26 to Jul 27
$130 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We stayed here during my daughter’s orientation. Great location! The staff were helpful and friendly. Would definitely stay here again!"

Reviewed on Jun 23, 2026

Opens in a new windowCambria Hotel Columbia Downtown The Vista
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jul 2 to Jul 3
$96 total
Jul 2 - Jul 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Everything was spectacular! Highly recommend"

Reviewed on Jun 25, 2026

Opens in a new windowHilton Garden Inn Columbia/Harbison
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Jun 28 to Jun 29
$100 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"Very comfortable stay."

Reviewed on Jun 25, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jul 2 to Jul 3
$123 total
Jul 2 - Jul 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
"Good staff"

Reviewed on Jun 25, 2026

Opens in a new windowCourtyard by Marriott Columbia Downtown at USC
La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

3 out of 5
1538 Horseshoe Drive Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Jul 2 to Jul 3
$99 total
Jul 2 - Jul 3
Total with taxes and fees
This smoke-free hotel includes 20 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
"Dan was one of the staff he is very nice he was very funny and he tried to help but the management did nothing the pool was absolutely disgusting it was filled with sand I reported it several times. the room had a odor we had to spray over and over again but overall it was okay Dan made it okay the ..."

Reviewed on Jun 23, 2026

Opens in a new window La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Jun 28 to Jun 29
$132 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Parking is very limited, as the parking lot is small, however, overall, the hotel is nice and in a convenient location."

Reviewed on Jun 25, 2026

Opens in a new windowHyatt Place Columbia/Downtown/The Vista
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Jun 28 to Jun 29
$92 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"Our room was clean and there was a decent breakfast spread. The hotel is under construction though, and we weren't aware of that ahead of time. It will look great when it's done!"

Reviewed on Jun 25, 2026

Opens in a new windowLa Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Jul 16 to Jul 17
$91 total
Jul 16 - Jul 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
"The staff was very helpful"

Reviewed on Jun 24, 2026

Opens in a new windowSleep Inn Columbia
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South Carolina Midlands hotels

Econo Lodge Rock Hill Northeast

Econo Lodge Rock Hill Northeast

914 Riverview Rd Rock Hill SC
$54 nightly
The price is $60 total per night from Jul 11 to Jul 12
$60 total
Jul 11 - Jul 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South Carolina Midlands hotel reviews by fellow wanderers

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Easy check in and out, close to 95, nice staff, place was clean, very good for the money, breakfast was very basic"
A verified traveler stayed at Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence

Explore More Ways to Travel with Travelocity