Book Hotels in South Carolina Midlands, SC

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Jul 24 - Jul 26
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Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Aug 9 to Aug 10
$116 total
Aug 9 - Aug 10
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"Everything was nice, except there was no closet, no microwave, no bathroom vent, and there was a broken shower knob frame in our bathroom. But very clean environment and friendly customer services."

Reviewed on Jul 23, 2026

Opens in a new windowTru By Hilton Columbia Downtown
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$80 nightly
The price is $89 total per night from Aug 16 to Aug 17
$89 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"The front desk staff is so friendly and welcoming. I am a travel Registered Nurse and I am always pleased with this hotel. It’s quiet, clean and comfortable."

Reviewed on Jul 22, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Aug 21 to Aug 22
$132 total
Aug 21 - Aug 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
"My shower was broken, hair dryer didn't work in the bathroom but worked from other outlets. Coffee was cold in the AM that I paid for at the restaurant"

Reviewed on Jul 23, 2026

Opens in a new windowCourtyard by Marriott Columbia Downtown at USC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Jul 26 to Jul 27
$100 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"I stayed overnight on a road trip. I chose the location bc of the proximity to the highway. I didn’t plan on using the amenities and I wasn’t expecting a Hilton, I just needed somewhere to lay my head for the night. This room was disgusting!!! Even for a “cheap” hotel. I did the bed bug check and ..."

Reviewed on Jul 23, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Jul 25 to Jul 26
$75 total
Jul 25 - Jul 26
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Just there for one night on a travel stop. From Texas to Virginia and on into Florida. By far THE cleanest property we have stayed at. Smelled a little musty when we first opened the door, but cleared out very quickly. Breakfast could have been a little better, but for the price we were completely ..."

Reviewed on Jul 23, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jul 30 to Jul 31
$96 total
Jul 30 - Jul 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowHilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Aug 23 to Aug 24
$105 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Opens in a new windowLa Quinta Inn by Wyndham Columbia SE / Fort Jackson
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Aug 2 to Aug 3
$132 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Opens in a new windowHyatt Place Columbia/Downtown/The Vista
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street Columbia SC
Fully refundable
$127 nightly
The price is $142 total per night from Aug 23 to Aug 24
$142 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowCambria Hotel Columbia Downtown The Vista
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South Carolina Midlands hotels

Econo Lodge Rock Hill Northeast

Econo Lodge Rock Hill Northeast

914 Riverview Rd Rock Hill SC
$47 nightly
The price is $52 total per night from Aug 13 to Aug 14
$52 total
Aug 13 - Aug 14
Total with taxes and fees
6.2/10 (929 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South Carolina Midlands hotel reviews by fellow wanderers

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Just there for one night on a travel stop. From Texas to Virginia and on into Florida. By far THE cleanest property we have stayed at. Smelled a little musty when we first opened the door, but cleared out very quickly. Breakfast could have been a little better, but for the price we were completely satisfied!"
A verified traveler stayed at Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence

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