Book Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands hotels
Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jul 26 to Jul 27
$109 total
Jul 26 - Jul 27
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"Overall excellent property"
Reviewed on Jul 16, 2026
Cambria Hotel Columbia Downtown The Vista
1000 Lady Street Columbia SC
Fully refundable
$127 nightly
The price is $142 total per night from Aug 9 to Aug 10
$142 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Great hotel. Centrally located, boutique hotel with wonderful amenities."
Reviewed on Jul 17, 2026
Tru By Hilton Columbia Greystone
185 Stoneridge Drive Columbia SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $111 total per night from Jul 26 to Jul 27
$111 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"Ice machine lacking please"
Reviewed on Jul 16, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jul 26 to Jul 27
$96 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"There are several dining options in the area which made it nice. The lobby was welcoming and staff were friendly. Breakfast was a bit pricey at the hotel so we chose to eat elsewhere."
Reviewed on Jul 16, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$80 nightly
The price is $89 total per night from Aug 9 to Aug 10
$89 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"Staff was very accomodating"
Reviewed on Jul 16, 2026
Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Jul 24 to Jul 25
$132 total
Jul 24 - Jul 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
"The room was clean, the staff was incredibly helpful and the pool was a nice place to relax in the heat. Everyone was friendly- we would definitely stay again next time."
Reviewed on Jul 16, 2026
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Jul 19 to Jul 20
$100 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Friendly staff, clean room."
Reviewed on Jul 16, 2026
Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Jul 26 to Jul 27
$132 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"So fun and clean"
Reviewed on Jul 16, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $96 total per night from Jul 19 to Jul 20
$96 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$47 nightly
The price is $52 total per night from Aug 6 to Aug 7
$52 total
Aug 6 - Aug 7
Total with taxes and fees
6.2/10 (928 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
12 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Howard Johnson by Wyndham Florence
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The rooms were clean. There wasn't much of anything to call breakfast."
A verified traveler stayed at Howard Johnson by Wyndham Florence
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