Book Hotels in South Carolina Midlands, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Nov 24 to Nov 25
$109 total
Nov 24 - Nov 25
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
"very professional approach to the visitors,the atmosphere was on point thank you again"
Reviewed on Nov 13, 2026

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$101 nightly
The price is $113 total per night from Dec 3 to Dec 4
$113 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Great hotel. Close to a lot of amenities!"
Reviewed on Nov 13, 2026

Clarion Pointe Rock Hill Near University
1106 N. Anderson Road Rock Hill SC
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Nov 29 to Nov 30
$81 total
Nov 29 - Nov 30
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public ...
"We stayed for one night only and did not use the amenities"
Reviewed on Nov 13, 2026

Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Nov 22 to Nov 23
$113 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
"Everything about our stay was exceptional from the staff to the room. We will choose them again."
Reviewed on Nov 7, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Dec 6 to Dec 7
$90 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"I inquired about the fitness facility vis text but then was told by the front desk there was none. The parking lot was bumpy and oddly placed."
Reviewed on Nov 13, 2026

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Nov 29 to Nov 30
$96 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Dec 13 to Dec 14
$69 total
Dec 13 - Dec 14
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...

Tru By Hilton Columbia Greystone
185 Stoneridge Drive Columbia SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $111 total per night from Nov 27 to Nov 28
$111 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...

Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
$71 nightly
The price is $80 total per night from Dec 6 to Dec 7
$80 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels

Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$50 nightly
The price is $57 total per night from Dec 4 to Dec 5
$57 total
Dec 4 - Dec 5
Total with taxes and fees
6.2/10 (962 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating

4 Star Hotels
13 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers

Tru By Hilton Columbia Downtown
5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"very professional approach to the visitors,the atmosphere was on point thank you again"
A verified traveler stayed at Tru By Hilton Columbia Downtown
Explore More Ways to Travel with Travelocity
- Hotels in Woodfield
- Hotels near Williams Brice Stadium
- Hotels in West Columbia
- Motel 6 West Columbia SC - Airport
- Hotels near University of South Carolina
- Hotels near Township Auditorium
- Hotels in Sumter
- Hotels near South Carolina State Fairgrounds
- Caravanparks in South Carolina Midlands
- Privatevacationhomes in South Carolina Midlands
- Motels in South Carolina Midlands
- Spa in South Carolina Midlands
- Romantic in South Carolina Midlands
- Pet Friendly in South Carolina Midlands
- Casino in South Carolina Midlands
- Beach in South Carolina Midlands
- Adults Only in South Carolina Midlands
- Cottages in South Carolina Midlands
- Cabins in South Carolina Midlands
- Bedandbreakfast in South Carolina Midlands
- Agritourism in South Carolina Midlands
- Houseboats in South Carolina
- Cabins in South Carolina
- Shandon Hotels
- Hotels near Sesquicentennial State Park
- Hotels near Riverbanks Zoo and Garden
- Hotels near Polo Road Ball Park
- Hotels near Palmetto Health Richland Hospital
- Hotels in Orangeburg
- Hotels in Lexington
- Hotels near Lake Murray
- Hotels near Koger Center for the Arts
- Hotels in Irmo
- Hotels near Holy Trinity Greek Orthodox Church
- Hotels near Hilton Field
- Hotels near Governor's Mansion
- Hotels near Fort Jackson
- Hotels in Forest Acres
- Hotels near Finlay Park
- Hotels near Eugene E Stone III Stadium
- Hotels in Elgin
- Downtown Columbia Hotels
- South Carolina Hotels
- Waterpark in South Carolina
- Ski in South Carolina
- Pet Friendly in South Carolina
- Indoor Pool in South Carolina
- Hot Tub in South Carolina
- Family Friendly in South Carolina
- Budget in South Carolina
- Beach in South Carolina
- All-Inclusive in South Carolina
- Richland County Hotels
- Hotels in Dentsville
- Hotels near Congaree National Park
- Hotels near Columbia Place Mall
- Motels in Columbia
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Columbia SC
- Hotels in Columbia
- Spa in Columbia
- Sleep Inn Near Ft Jackson
- Pet Friendly in Columbia
- Motel 6 Columbia SC - Fort Jackson Area
- Luxury in Columbia
- InTown Suites Extended Stay Columbia SC - Two Notch
- InTown Suites Extended Stay Columbia SC - Broad River
- Smoking in Columbia
- Kitchenette in Columbia
- Indoor Pool in Columbia
- Hot Tub in Columbia
- Free Airport Transportation in Columbia
- Balcony in Columbia
- Suites in Columbia
- Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
- Graduate by Hilton Columbia SC
- Comfort Suites Columbia at Harbison
- Budget in Columbia
- Aparthotels in Columbia
- Hotels near Colonial Life Arena
- Hotels near Charlie W Johnson Stadium
- Hotels in Cayce
- Hotels in Camden
- Hotels in Blythewood
- Hotels in Arthurtown













