Book Hotels in South Carolina Midlands, SC

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Top South Carolina Midlands hotels

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jun 7 to Jun 8
$112 total
Jun 7 - Jun 8
Total with taxes and fees
A gym is featured at this hotel, along with self parking. Guests will appreciate free perks like daily breakfast and WiFi in public areas. Staff at the 24-hour ...
Great place to stay.

Reviewed on May 13, 2026

Opens in a new windowTru By Hilton Columbia Downtown
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jun 7 to Jun 8
$96 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Bvrty

Reviewed on May 14, 2026

Opens in a new windowHilton Garden Inn Columbia/Harbison
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$76 nightly
The price is $85 total per night from May 25 to May 26
$85 total
May 25 - May 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Extremely friendly staff at the front desk. Room was clean but shower floor could really use a good scrub. Overall, our stay was fantastic. Would definitely visit again.

Reviewed on May 14, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from May 21 to May 22
$132 total
May 21 - May 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
Clean very nice room and lobby.

Reviewed on May 14, 2026

Opens in a new windowCourtyard by Marriott Columbia Downtown at USC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from May 24 to May 25
$75 total
May 24 - May 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean comfortable and convenient. The staff was friendly, I could walk to the Starbucks and restaurants. The room was very clean. The bed was very comfortable. Great for this weary traveler.

Reviewed on May 14, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from May 24 to May 25
$106 total
May 24 - May 25
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Best night’s sleep I’ve had in forever!! Very pleasant staff! Clean! Will definitely be making this our go to for our trips to Florida and back!!!

Reviewed on May 14, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from May 24 to May 25
$132 total
May 24 - May 25
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Great location and comfort for my stay.

Reviewed on May 5, 2026

Opens in a new windowHyatt Place Columbia/Downtown/The Vista
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Jun 4 to Jun 5
$91 total
Jun 4 - Jun 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
.

Reviewed on May 14, 2026

Opens in a new windowSleep Inn Columbia
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from May 24 to May 25
$88 total
May 24 - May 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Great property, clean and staff was very helpful.

Reviewed on May 14, 2026

Opens in a new windowLa Quinta Inn by Wyndham Columbia SE / Fort Jackson
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South Carolina Midlands hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South Carolina Midlands hotel reviews by fellow wanderers

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