Book Hotels in Herculaneum, MO
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Top Herculaneum hotels

The Principal Hotel
310 S Main St, Columbia, IL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Aug 25 to Aug 26
$123 total
Aug 25 - Aug 26
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
"Overall was the best stay we have had with any one. The only downside would be no hot breakfast unless you went to the restaurant on location. Staff was great and so helpful when we needed anything for the room."
Reviewed on Aug 18, 2025

The Lodge at Grant's Trail
4398 Hoffmeister Ave., St. Louis, MO
$139 nightly
The price is $160 total per night from Sep 21 to Sep 22
$160 total
Sep 21 - Sep 22
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace and wedding services are also provided.
"The Lodge has been our first choice when we need to stay overnight for my spouse's medical appointments in St. Louis. It's proximity to I-55 makes it easy to locate. The property is amazing both inside and outside. We have been fortunate have Clark on several of our visits and he always gives us ..."
Reviewed on Aug 20, 2025

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
4250 Midamerica Lane, St. Louis, MO
Fully refundable
$118 nightly
The price is $136 total per night from Aug 24 to Aug 25
$136 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"I have stayed at this property multiple times and it’s always a good experience. The staff are friendly and do an excellent job at keeping up the facility. I look forward to returning."
Reviewed on Aug 19, 2025

Hampton Inn & Suites St. Louis/South I-55
4200 Midamerica Lane, St. Louis, MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Sep 1 to Sep 2
$144 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
"Jacqueline was amazing . We will be back to visit in the future"
Reviewed on Aug 21, 2025

Pear Tree Inn St. Louis Arnold
1201 Drury Ln, Arnold, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $104 total per night from Aug 27 to Aug 28
$104 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Parking space was limited and narrow. I drive a truck and had difficulty finding a space to accommodate my vehicle. Everything else was above average."
Reviewed on Aug 20, 2025

River City Casino & Hotel
777 River City Casino Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Aug 24 to Aug 25
$133 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
"Excellent views of the Mississippi River. Nice casino! My room was very nice also."
Reviewed on Aug 20, 2025

Best Western Plus Fenton
1680 Fenton Business Park Ct, Fenton, MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $120 total per night from Sep 1 to Sep 2
$120 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Nice night stay
"The room was really nice and updated. A few of the floor tiles were cracked and there was hair on the floor in the bathroom but overall it was in good condition. Breakfast was good and the lobby was clean and staff was friendly."
Reviewed on Aug 9, 2025

Best Western St. Louis Inn
6224 Heimos Industrial Park Dr, St. Louis, MO
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Aug 27 to Aug 28
$85 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Nice, clean, convenient, friendly staff"
Reviewed on Aug 20, 2025

Americas Best Value Inn St. Louis South
6602 S Lindbergh Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Aug 24 to Aug 25
$86 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
quiet and great experience
"my experience was good with friendly staff"
Reviewed on Jul 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Herculaneum hotel reviews by fellow wanderers

Hampton Inn & Suites St. Louis/South I-55
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Jacqueline was amazing . We will be back to visit in the future "
A verified traveler stayed at Hampton Inn & Suites St. Louis/South I-55
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