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Sep 4 - Sep 6
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Top hotels in Medical Center

Atheneum Suite Hotel

Atheneum Suite Hotel

4 out of 5
1000 Brush Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $196 total per night from Aug 31 to Sep 1
$196 total
Aug 31 - Sep 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"Hotel is nice and close to Greek Town and Ford Field where the concert was."

Reviewed on Aug 30, 2026

Opens in a new windowAtheneum Suite Hotel
The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

4 out of 5
1509 Broadway St. Detroit MI
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $197 total per night from Sep 8 to Sep 9
$197 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel features a restaurant and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a garden are also offered.
"The property has such character and a welcoming atmosphere. We visited for one night's stay to attend a concert at Ford Field. That was amazing to be a close walking distance to the event and to be surrounded by great bars and restaurants in the area made this a great place to stay in the middle ..."

Reviewed on Aug 30, 2026

Opens in a new windowThe Siren Hotel, an Ash Hotel
MotorCity Casino Hotel

MotorCity Casino Hotel

4.5 out of 5
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $231 total per night from Aug 31 to Sep 1
$231 total
Aug 31 - Sep 1
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
"Every staff member we encountered was kind and very welcoming. Check in / check out was a breeze. Rooms were very clean. Close to so much down town. Thank you"

Reviewed on Aug 30, 2026

Opens in a new windowMotorCity Casino Hotel
Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel

3.5 out of 5
2 Washington Blvd Detroit MI
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $167 total per night from Sep 20 to Sep 21
$167 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"Staff was very professional and nice. The hotel itself was very nice and clean but the room had a old but updated feel. The only real disappointment was that our room was on the west side of the building and when we checked in, in the late afternoon, the blinds had been left open and the sun had ..."

Reviewed on Aug 30, 2026

Opens in a new windowFort Pontchartrain Detroit, a Wyndham Hotel
Hollywood Casino at Greektown

Hollywood Casino at Greektown

4 out of 5
1200 Saint Antoine St Detroit MI
Fully refundableReserve now, pay when you stay
$185 nightly
The price is $215 total per night from Aug 31 to Sep 1
$215 total
Aug 31 - Sep 1
Total with taxes and fees
A casino, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 10 conference rooms, business ...
"Arrived at 2:30 was told can check in until 4. Came back at 4 the line was wrapped throughout the lobby and out the door probably a hundred people. With 2 workers the line wasn’t moving. Had to leave and come back after concert. When we came back after waiting in another line to find out they over ..."

Reviewed on Aug 30, 2026

Opens in a new windowHollywood Casino at Greektown
La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport

3 out of 5
30847 Flynn Drive Romulus MI
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Sep 8 to Sep 9
$106 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage ...
"Front desk staff was very rude, curtains dirty, funny smell in the room"

Reviewed on Aug 30, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Detroit Metro Airport
Hotel Houze Detroit Downtown

Hotel Houze Detroit Downtown

3 out of 5
305 Michigan Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Sep 2 to Sep 3
$121 total
Sep 2 - Sep 3
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
"Clean unit. Weird that it has a full kitchen but no utensils and the room we had, the bed was 8” from an awkward corner so navigating around the far side of the bed was dangerous. But the change in management where they have a staffed entrance now instead of a code to get into the building is an ..."

Reviewed on Aug 30, 2026

Opens in a new windowHotel Houze Detroit Downtown
Trumbull and Porter Hotel

Trumbull and Porter Hotel

3.5 out of 5
1331 Trumbull St Detroit MI
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $146 total per night from Aug 31 to Sep 1
$146 total
Aug 31 - Sep 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowTrumbull and Porter Hotel
Hotel Indigo Detroit Downtown by IHG

Hotel Indigo Detroit Downtown by IHG

3.5 out of 5
1020 Washington Blvd Detroit MI
Fully refundable
$163 nightly
The price is $189 total per night from Sep 3 to Sep 4
$189 total
Sep 3 - Sep 4
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowHotel Indigo Detroit Downtown by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Medical Center hotel reviews by fellow wanderers

The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"The property has such character and a welcoming atmosphere. We visited for one night's stay to attend a concert at Ford Field. That was amazing to be a close walking distance to the event and to be surrounded by great bars and restaurants in the area made this a great place to stay in the middle of the action. Downtown Detroit has such a great vibe. Definitely give The Siren a try if you are a fan of a boutique hotel experience."
A verified traveler stayed at The Siren Hotel, an Ash Hotel
The Siren Hotel, an Ash Hotel

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