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Top hotels in Medical Center

Atheneum Suite Hotel

Atheneum Suite Hotel

4 out of 5
1000 Brush Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $191 total per night from Mar 8 to Mar 9
$191 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Outstanding hotel. Amazing staff. Great rooms. Convenient shuttle service. Excellent bar.

Reviewed on Mar 5, 2026

Opens in a new windowAtheneum Suite Hotel
The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

4 out of 5
1509 Broadway St. Detroit MI
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $148 total per night from Mar 17 to Mar 18
$148 total
Mar 17 - Mar 18
Total with taxes and fees
This hotel features a restaurant and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a garden are also offered.
Very small room and extremely small shower. Very unhappy that the property would not refund 1 day of prepaid 3 day stay, despite widespread airline cancellations making it impossible to arrive as planned.

Reviewed on Mar 4, 2026

Opens in a new windowThe Siren Hotel, an Ash Hotel
The Godfrey Detroit, Curio Collection By Hilton

The Godfrey Detroit, Curio Collection By Hilton

4 out of 5
1401 Michigan Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $151 total per night from Mar 29 to Mar 30
$151 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. WiFi in public areas is free. Valet parking, a coffee shop, and ...
The hospitality staff, concierge , and valet were exceptional top quality service. Parking is risky and a gamble. Front desk lady was not kind, polite, or personable.

Reviewed on Mar 4, 2026

Opens in a new windowThe Godfrey Detroit, Curio Collection By Hilton
MotorCity Casino Hotel

MotorCity Casino Hotel

4.5 out of 5
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $194 total per night from Apr 5 to Apr 6
$194 total
Apr 5 - Apr 6
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
Staff

Reviewed on Mar 5, 2026

Opens in a new windowMotorCity Casino Hotel
Hollywood Casino at Greektown

Hollywood Casino at Greektown

4 out of 5
1200 Saint Antoine St Detroit MI
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $185 total per night from Mar 9 to Mar 10
$185 total
Mar 9 - Mar 10
Total with taxes and fees
A casino, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 10 conference rooms, business ...
Thin walls, could hear just about everything from the neighboring room. Late night yelling in hallway and disrespectful occupants.

Reviewed on Mar 5, 2026

Opens in a new windowHollywood Casino at Greektown
MGM Grand Detroit

MGM Grand Detroit

4.5 out of 5
1777 3rd Street Detroit MI
$194 nightly
The price is $225 total per night from Apr 1 to Apr 2
$225 total
Apr 1 - Apr 2
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 7 restaurants. Traveling on business? Take advantage of the express check-in, express check-out, ...
Room was excellent and front desk staff very friendly!

Reviewed on Mar 4, 2026

Opens in a new windowMGM Grand Detroit
La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport

3 out of 5
30847 Flynn Drive Romulus MI
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $97 total per night from Mar 8 to Mar 9
$97 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage ...
Clean room. Attentive desk staff the minute we walked it. Easy check in and they provided discounted airport parking

Reviewed on Mar 4, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Detroit Metro Airport
Hotel Houze Detroit Downtown

Hotel Houze Detroit Downtown

3 out of 5
305 Michigan Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Mar 8 to Mar 9
$121 total
Mar 8 - Mar 9
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
Staff was amazing & the city view room was perfect for valentine’s day!

Reviewed on Mar 5, 2026

Opens in a new windowHotel Houze Detroit Downtown
Radisson Hotel Detroit Metro Airport

Radisson Hotel Detroit Metro Airport

3 out of 5
8800 Wickham Rd Romulus MI
Fully refundable
$76 nightly
The price is $87 total per night from Mar 11 to Mar 12
$87 total
Mar 11 - Mar 12
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free ...
Quick checkin and check out. Nice and comfortable room. Efficient airport service. I would like to have a breakfast option.

Reviewed on Mar 3, 2026

Opens in a new windowRadisson Hotel Detroit Metro Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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