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Top hotels in Medical Center
Atheneum Suite Hotel
1000 Brush Avenue Detroit MI
$175 nightly
The price is $203 total per night from May 3 to May 4
$203 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Huge rooms that would be great for a family. The big lobby was a great place to hang out after we saw a show. Rooms were clean but not *sparkling* clean. The glasses in the bathroom looked kinda cloudy, for instance. Also it’s $6 for a black coffee in the morning, and you might have to wait a long ...
Reviewed on May 1, 2026
The Siren Hotel, an Ash Hotel
1509 Broadway St. Detroit MI
$135 nightly
The price is $153 total per night from May 17 to May 18
$153 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a garden are also offered.
The room was spectacular - I stayed in the Parlor room on the 12th floor. I had a view of Comerica Park and Ford Field. The staff were incredibly helpful and friendly, and the restaurants were all amazing (I visited all three). I would highly recommend this hotel! The only downside is there was not ...
Reviewed on Apr 29, 2026
MotorCity Casino Hotel
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
$216 nightly
The price is $251 total per night from May 3 to May 4
$251 total
May 3 - May 4
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
Great staff!!
Reviewed on May 1, 2026
Hollywood Casino at Greektown
1200 Saint Antoine St Detroit MI
Fully refundableReserve now, pay when you stay
$190 nightly
The price is $220 total per night from May 3 to May 4
$220 total
May 3 - May 4
Total with taxes and fees
A casino, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 10 conference rooms, business ...
staff was great.
Reviewed on May 1, 2026
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
30847 Flynn Drive Romulus MI
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $102 total per night from May 4 to May 5
$102 total
May 4 - May 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage ...
Shower floor needed a good scrubbing, otherwise the room appeared clean and neat. The breakfast was a disappointment…warming trays were empty…not sure what should have been there…eggs? Meat? Already peeled hard cooked eggs were good. Juice pitchers were empty. Mixed fruit would have been nice. Shuttle ...
Reviewed on May 2, 2026
MGM Grand Detroit
1777 3rd Street Detroit MI
$213 nightly
The price is $247 total per night from May 7 to May 8
$247 total
May 7 - May 8
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 7 restaurants. Traveling on business? Take advantage of the express check-in, express check-out, ...
Smelt like weed by my room , weird people hanging b y my room. I want my refund, you promised. Also don’t forget you changed me for a resort fee , nothing we open.
Reviewed on Apr 30, 2026
Trumbull and Porter Hotel
1331 Trumbull St Detroit MI
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $153 total per night from May 17 to May 18
$153 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Nice hotel the rooms are not really has upscale as I would have expected for the amount they charge and my room had a bit of ant problem in the bathroom that I did share with the property about but overall the stay was great and staff was great and very friendly and helpful unsure it would go again ...
Reviewed on Apr 30, 2026
Hotel Indigo Detroit Downtown by IHG
1020 Washington Blvd Detroit MI
Fully refundable
$184 nightly
The price is $213 total per night from May 17 to May 18
$213 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Our group of 25 all stayed at hotel Indigo for a conference and had a great experience! The walk down to the conference center was super easy and there were many bus stops super close by to get anywhere we wanted to go! The staff was awesome and even helped us check in early! The beds were comfy ...
Reviewed on Apr 30, 2026
Hotel Houze Detroit Downtown
305 Michigan Avenue Detroit MI
$117 nightly
The price is $132 total per night from May 17 to May 18
$132 total
May 17 - May 18
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
Staff was fun and had excellent customer service . Room could've been cleaner but it was decent for one night !
Reviewed on May 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Medical Center Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Medical Center hotel reviews by fellow wanderers
Shinola Hotel
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Give Hassan a raise he is excellent"
A verified traveler stayed at Shinola Hotel
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