Find a Hotel in Central West End
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Top hotels in Central West End

Drury Plaza Hotel St. Louis at the Arch
Very nice staff and great atmosphere. Quietest hotel room i have ever stayed in
Reviewed on Mar 10, 2026

The Royal Sonesta Chase Park Plaza St. Louis
Dust in bathroom baseboards and on TV’s. 80 dollars for overnight parking with hotel or 40 with parking garage. Room service is convenient but a bit overpriced.
Reviewed on Mar 10, 2026

AC Hotel St. Louis Central West End
The hotel is new; very clean, staff are super friendly and great location. This is our second time in 6 months - favorite hotel in central west end!
Reviewed on Mar 9, 2026

21C Museum Hotel St Louis
Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones.
Reviewed on Mar 11, 2026

Clayton Plaza Hotel & Extended Stay
This is an older property, but very clean, comfortable, spacious and convenient to downtown Clayton. Parking was convenient and free on the weekend. Breakfast was better than average, with chef-made omelets and waffles.
Reviewed on Mar 11, 2026

The West End
Very welcoming staff, hotel was clean
Reviewed on Mar 2, 2026

Aloft St. Louis Cortex
Everything was great except parking.
Reviewed on Mar 11, 2026

Hotel Indigo St Louis - Central West End by IHG
nice
Reviewed on Mar 10, 2026

DoubleTree by Hilton St. Louis Forest Park
When we checked into the hotel, our room was 77°. The front desk was called three times and an employee did come up to “reset” the thermometer. We were told no other rooms were available and the room was still 77° when we checked out the next day.
Reviewed on Mar 10, 2026
Central West End Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Central West End area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Central West End to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Central West End are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Central West End hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch
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