Explore 120 Luxury Hotels in Florida Keys
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Best Luxury Hotels in Florida Keys
H2O Suites - Adults Only
1212 Simonton Street, Key West, FL
$339 nightly
The price is $381 total per night from Aug 5 to Aug 6
$381 total
Aug 5 - Aug 6
Total includes taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (542 reviews)
"The star was very accommodating."
Reviewed on Jun 25, 2025
The Marker Key West Harbor Resort
200 William Street, Key West, FL
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $275 total per night from Aug 12 to Aug 13
$275 total
Aug 12 - Aug 13
Total includes taxes and fees
This eco-certified hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
9/10 Wonderful! (1,004 reviews)
"The staff was excellent!"
Reviewed on Jul 19, 2025
Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Fully refundableReserve now, pay when you stay
$320 nightly
The price is $361 total per night from Aug 21 to Aug 22
$361 total
Aug 21 - Aug 22
Total includes taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
9/10 Wonderful! (1,137 reviews)
"Stayed here for one night. Unfortunately the weather wasn’t great so we didn’t get to experience the pool areas and such. We walked around the grounds at night in the rain and it was still breath taking. Would love to stay longer the next time I am back in the area."
Reviewed on Jul 20, 2025
Oceans Edge Key West Resort, Hotel & Marina
5950 Peninsular Avenue, Key West, FL
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $233 total per night from Aug 18 to Aug 19
$233 total
Aug 18 - Aug 19
Total includes taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,691 reviews)
"The only negative thing I can say; is that the A/C in our room didn’t work to well or it was just that hot!"
Reviewed on Jul 20, 2025
Parmer's Resort
565 Barry Avenue, Summerland Key, FL
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $200 total per night from Aug 10 to Aug 11
$200 total
Aug 10 - Aug 11
Total includes taxes and fees
The private beach and marina are among the highlights at this motel. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. Enjoy ...
8.8/10 Excellent! (1,001 reviews)
"Very nice place."
Reviewed on Jul 19, 2025
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Fully refundable
$252 nightly
The price is $283 total per night from Aug 14 to Aug 15
$283 total
Aug 14 - Aug 15
Total includes taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,615 reviews)
"The property location was ideal. The room was comfortable and clean. The elevators weren’t working during our stay, so that was a bummer. Otherwise, the staff was great and the property was beautiful. I would stay here again."
Reviewed on Jul 19, 2025
Casa Marina Key West, Curio Collection by Hilton
1500 Reynolds Street, Key West, FL
Fully refundableReserve now, pay when you stay
$258 nightly
The price is $290 total per night from Aug 6 to Aug 7
$290 total
Aug 6 - Aug 7
Total includes taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.4/10 Very Good! (244 reviews)
"Pictures on the website did not do it just this beautiful property inside and out"
Reviewed on Jul 21, 2025
Kingsail Resort
7050 Overseas Highway, Marathon, FL
$85 nightly
The price is $95 total per night from Aug 10 to Aug 11
$95 total
Aug 10 - Aug 11
Total includes taxes and fees
A marina and an outdoor pool are featured at this smoke-free motel. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
8.4/10 Very Good! (1,022 reviews)
"Wonderful stay! 😍"
Reviewed on Jul 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More 4 star hotels in Florida Keys
The Islands of Islamorada
82779 Old Hwy, Islamorada, FL
$594 nightly
The price is $668 total per night from Aug 1 to Aug 2
$668 total
Aug 1 - Aug 2
Total includes taxes and fees
9.6/10 Exceptional! (62 reviews)
5 star hotels in Florida Keys
Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
$320 nightly
The price is $361 total per night from Aug 21 to Aug 22
$361 total
Aug 21 - Aug 22
Total includes taxes and fees
9/10 Wonderful! (1,137 reviews)
Florida Keys Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Florida Keys luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Florida Keys to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Florida Keys will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Florida Keys, and plan your next opulent escape.
Florida Keys hotels essential information
Accommodation | 8,273 hotels |
|---|---|
Lowest Price | $95 |
Highest Price | $668 |
Popular hotels | Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Cheeca Lodge & Spa, Casa Marina Key West, Curio Collection by Hilton, Kingsail Resort, Southernmost Beach Resort and Guesthouses, Parmer's Resort, H2O Suites - Adults Only |
Popular Luxury Stays in Florida Keys
Recent Florida Keys Hotel Reviews By Fellow Wanderers
Holiday Inn Key Largo by IHG
5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Traveled to the keys for the weekend to look at a venue for my son’s wedding. This hotel was quite pleasant and the service was nice and accommodating and there was a restaurant on site as well as off and many local. There pool with the bar was a nice feature as well! "
A verified traveler stayed at Holiday Inn Key Largo by IHG
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- Old Town Key West Hotels
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Areas of Florida Keys
- Key West Hotels
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- Marathon Hotels
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- Islamorada Hotels
- Key Colony Beach Hotels
- Tavernier Hotels
- Coral Gables Hotels
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