Explore top 2025 5 Star Hotels in Ohio River Valley

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Top Ohio River Valley 5 Star hotels

Le Méridien Columbus, The Joseph

Le Méridien Columbus, The Joseph

5 out of 5
620 North High Street, Columbus, OH
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $171 total per night from Sep 21 to Sep 22
$171 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the laundry service, conference space, and valet ...
Le Méridien Columbus, The Joseph
Conrad Indianapolis

Conrad Indianapolis

5 out of 5
50 W Washington St., Indianapolis, IN
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $239 total per night from Oct 6 to Oct 7
$239 total
Oct 6 - Oct 7
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Conrad Indianapolis
Jungle Fever

Jungle Fever

5 out of 5
254-256 West Poplar Avenue, Columbus, OH
$168 nightly
The price is $177 total per night from Sep 14 to Sep 15
$177 total
Sep 14 - Sep 15
Total with taxes and fees
In-room fitness is featured at this vacation home, along with free WiFi in public areas and a snack bar/deli. A business center, luggage storage, and laundry ...
Jungle Fever
Jungle Casa Lundy

Jungle Casa Lundy

5 out of 5
31-33 Lundy Street, Columbus, OH
In-room fitness is featured at this vacation home, along with free WiFi in public areas and a terrace. Business travelers can take advantage of the business ...
Jungle Casa Lundy
Jungalow

Jungalow

5 out of 5
96-98 Brickel Street, Columbus, OH
$134 nightly
The price is $141 total per night from Sep 23 to Sep 24
$141 total
Sep 23 - Sep 24
Total with taxes and fees
In-room fitness is featured at this vacation home, along with free WiFi in public areas and a snack bar/deli. A business center, dry cleaning, and barbecue grills ...
Jungalow
The Jungle Oasis

The Jungle Oasis

5 out of 5
605 Dennison Avenue, Columbus, OH
$99 nightly
The price is $104 total per night from Sep 11 to Sep 12
$104 total
Sep 11 - Sep 12
Total with taxes and fees
In-room fitness is featured at this vacation home, along with free WiFi in public areas and a snack bar/deli. Business travelers can take advantage of the business ...
The Jungle Oasis
Louisville Bourbon Inn

Louisville Bourbon Inn

5 out of 5
1332 S 4th St, Louisville, KY
$265 nightly
The price is $308 total per night from Sep 15 to Sep 16
$308 total
Sep 15 - Sep 16
Total with taxes and fees
This bed & breakfast features free WiFi in public areas, wedding services, and free self parking. Enjoy the free full breakfast each morning. A communal living ...
Louisville Bourbon Inn
Jungle Gem Master house

Jungle Gem Master house

5 out of 5
27-29 Lundy St, Columbus, OH
In-room fitness, free self parking, and laundry facilities are featured at this vacation home. Business travelers can take advantage of the business center. ...
Jungle Gem Master house
The Jungle Book

The Jungle Book

5 out of 5
621 Dennison Avenue, Columbus, OH
$130 nightly
The price is $137 total per night from Sep 24 to Sep 25
$137 total
Sep 24 - Sep 25
Total with taxes and fees
In-room fitness is featured at this vacation home, along with free WiFi in public areas and a snack bar/deli. Business travelers can take advantage of the business ...
The Jungle Book
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Ohio River Valley Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Ohio River Valley to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Ohio River Valley 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Ohio River Valley before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.