Explore the best 2025 4 Star Hotels Hotels in Ohio River Valley

Name: JW Marriott Indianapolis
Price range: $228 total

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Top Ohio River Valley 4 Star hotels

Hyatt Regency Cincinnati

151 West Fifth Street, Cincinnati, OH

Free Cancellation

Reserve now, pay when you stay

$159 nightly

$190 total

Aug 31 - Sep 1

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a gym on site, and concierge services and free newspapers are also offered.

Pool

Pet friendly

Hilton Cincinnati Netherland Plaza

35 W 5th St, Cincinnati, OH

Free Cancellation

Reserve now, pay when you stay

$132 nightly

$157 total

Sep 15 - Sep 16

Total with taxes and fees

This historic hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Self parking, a hair salon, and express check-out are also offered.

Pet friendly

Free WiFi

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

Free Cancellation

Reserve now, pay when you stay

$135 nightly

$159 total

Aug 31 - Sep 1

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the seasonal outdoor pool, bar/lounge, and snack bar/deli.

Pool

Spa

I Hotel And Illinois Conference Center

1900 South First Street, Champaign, IL

Free Cancellation

Reserve now, pay when you stay

$99 nightly

$112 total

Aug 31 - Sep 1

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like continental breakfast and valet parking.

Breakfast included

Spa

Ironworks Hotel Indy

2721 E 86th Street, Indianapolis, IN

Free Cancellation

Reserve now, pay when you stay

$175 nightly

$205 total

Sep 4 - Sep 5

Total with taxes and fees

This smoke-free hotel's 4 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Free self parking, a coffee shop, and dry cleaning are also offered.

Spa

Pet friendly

Wyndham Columbus

175 Hutchinson Ave, Columbus, OH

Free Cancellation

Reserve now, pay when you stay

$70 nightly

$83 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Enjoy the hot tub and perks like free self parking.

Pool

Hot Tub

Omni Louisville Hotel

400 S. 2nd Street, Louisville, KY

Free Cancellation

Reserve now, pay when you stay

$185 nightly

$218 total

Aug 29 - Aug 30

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and visit the 3 bars/lounges and poolside bar for drinks.

The Westin Cincinnati

21 E 5th St, Cincinnati, OH

Free Cancellation

Reserve now, pay when you stay

$135 nightly

$161 total

Aug 28 - Aug 29

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. Self parking, a coffee shop, and dry cleaning are also offered.

Pet friendly

Restaurant

Sonesta Columbus Downtown

33 E Nationwide Blvd, Columbus, OH

Free Cancellation

Reserve now, pay when you stay

$136 nightly

$160 total

Sep 21 - Sep 22

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. Self parking, a snack bar/deli, and a grocery/convenience store are also offered.

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

Free Cancellation

Reserve now, pay when you stay

$122 nightly

$143 total

Aug 30 - Aug 31

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet parking, a 24-hour business center, and a grocery/convenience store are also offered.

Pool

Breakfast included

Sheraton Indianapolis Hotel at Keystone Crossing

8787 Keystone Crossing, Indianapolis, IN

Free Cancellation

Reserve now, pay when you stay

$87 nightly

$102 total

Aug 24 - Aug 25

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a bar/lounge on site, and laundry facilities and concierge services are also provided.

JW Marriott Indianapolis

10 S West Street, Indianapolis, IN

Free Cancellation

Reserve now, pay when you stay

$195 nightly

$228 total

Aug 27 - Aug 28

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Self parking, a coffee shop, and a snack bar/deli are also offered.

Free WiFi

Restaurant

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Ohio River Valley

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Ohio River Valley 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Ohio River Valley will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Ohio River Valley, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Ohio River Valley hotels essential information

Accommodation	19,498 hotels
Lowest Price	$83
Highest Price	$228
Popular hotels	Hyatt Regency Cincinnati, Hilton Cincinnati Netherland Plaza, Galt House Hotel Trademark Collection by Wyndham, I Hotel And Illinois Conference Center, Ironworks Hotel Indy, Wyndham Columbus, Omni Louisville Hotel, The Westin Cincinnati, Sonesta Columbus Downtown, Embassy Suites Louisville Downtown, Sheraton Indianapolis Hotel at Keystone Crossing, JW Marriott Indianapolis