Explore top 2026 5 Star Hotels in Mission District

Name: Hotel Drisco
Price range: $618 total
Rating: 9.8

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Top Mission District 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA

$324 nightly

$381 total

Jan 25 - Jan 26

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

9/10 Wonderful! (1,446 reviews)

The entire stay was amazing. This is truly a 5 star hotel.

Reviewed on Jan 15, 2026

Claremont Resort & Club

41 Tunnel Road Berkeley CA

Fully refundableReserve now, pay when you stay

$304 nightly

$344 total

Jan 21 - Jan 22

Total with taxes and fees

This luxury hotel features 3 restaurants, 3 outdoor pools, and 8 outdoor tennis courts. Bring the family and enjoy the children's club, playground, and kid-friendly ...

8.8/10 Excellent! (1,009 reviews)

Special place. Great service. Nice room. If you are a fan of The Shining, check this place out

Reviewed on Jan 19, 2026

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St San Francisco CA

Fully refundableReserve now, pay when you stay

$314 nightly

$370 total

Feb 20 - Feb 21

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,000 reviews)

Service, cleanliness

Reviewed on Jan 3, 2026

Taj Campton Place

340 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$208 nightly

$244 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,003 reviews)

Home away from home. Cozy bar , great front desk staff.

Reviewed on Jan 15, 2026

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

Fully refundableReserve now, pay when you stay

$395 nightly

$465 total

Jan 23 - Jan 24

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (998 reviews)

When balancing things the Four Seasons simply stands out. It is the little things that matter and here they know these details. It is as if you are coming home.

Reviewed on Jan 14, 2026

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$431 nightly

$507 total

Jan 30 - Jan 31

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.2/10 Wonderful! (1,000 reviews)

Staff were great, our room was amazing!

Reviewed on Jan 10, 2026

1 Hotel San Francisco

8 Mission St San Francisco CA

Fully refundableReserve now, pay when you stay

$447 nightly

$526 total

Feb 12 - Feb 13

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9/10 Wonderful! (501 reviews)

Great location. Rooms are a good size. Gym is a little small and was packed most mornings.

Reviewed on Jan 13, 2026

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St San Francisco CA

Fully refundableReserve now, pay when you stay

$429 nightly

$505 total

Feb 13 - Feb 14

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

9.4/10 Exceptional! (1,000 reviews)

Top flight service, amenities, room and view.

Reviewed on Jan 13, 2026

The St. Regis San Francisco

125 3rd St San Francisco CA

Fully refundableReserve now, pay when you stay

$437 nightly

$515 total

Jan 24 - Jan 25

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.2/10 Wonderful! (701 reviews)

The service was spectacular, enjoyed the restaurant as well as room service, and the room was very clean and spacious

Reviewed on Dec 25, 2025

Hotel Drisco

2901 Pacific Avenue San Francisco CA

Fully refundableReserve now, pay when you stay

$531 nightly

$618 total

Feb 1 - Feb 2

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the business center. ...

9.8/10 Exceptional! (456 reviews)

Service and breakfast

Reviewed on Jan 9, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.