Explore top 2026 4 Star Hotels in Roxana

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Top Roxana 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $166 total per night from Jun 19 to Jun 20
$166 total
Jun 19 - Jun 20
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,110 reviews)
"Good location, right by the arch. Short walk to Busch stadium. Hotel has 3 restaurants with bars. Covered parking garage with easy in and out adjacent to the hotel."

Reviewed on Jun 13, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
$135 nightly
The price is $158 total per night from Jul 9 to Jul 10
$158 total
Jul 9 - Jul 10
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,107 reviews)
"Harry, clean room, everything was dazzling, clean.Every creature."

Reviewed on Jun 13, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
$152 nightly
The price is $179 total per night from Jul 5 to Jul 6
$179 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (725 reviews)
"Dinning and pool areas were enjoyable."

Reviewed on Jun 2, 2026

Opens in a new windowLe Méridien St. Louis Clayton
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $219 total per night from Jun 14 to Jun 15
$219 total
Jun 14 - Jun 15
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,021 reviews)
"A nice hotel and well managed"

Reviewed on Jun 12, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $183 total per night from Jun 21 to Jun 22
$183 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,907 reviews)
"Nice place"

Reviewed on Jun 12, 2026

Opens in a new window21C Museum Hotel St Louis
Marriott St. Louis Grand

Marriott St. Louis Grand

4 out of 5
800 Washington Ave St. Louis MO
$152 nightly
The price is $181 total per night from Jun 26 to Jun 27
$181 total
Jun 26 - Jun 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,022 reviews)
"Property was great- my only complaint was the bed was so saggy in the middle you could visually see it- and it made it difficult to sleep it was so bad."

Reviewed on Jun 10, 2026

Opens in a new windowMarriott St. Louis Grand
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Jun 21 to Jun 22
$189 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,222 reviews)
"Always just wonderful. We stay here often. There is no better way to experience Busch Stadium than Live by Loews."

Reviewed on Jun 10, 2026

Opens in a new windowLive by Loews - St.Louis
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4 out of 5
1 S Broadway St. Louis MO
$155 nightly
The price is $184 total per night from Jun 20 to Jun 21
$184 total
Jun 20 - Jun 21
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
7.6/10 Good! (1,163 reviews)
"Room wasn’t ready til after 6pm. Everything else was a problem as well"

Reviewed on Jun 13, 2026

Opens in a new windowHilton St. Louis at the Ballpark
The Cheshire

The Cheshire

4 out of 5
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $191 total per night from Jun 21 to Jun 22
$191 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.8/10 Excellent! (1,023 reviews)
"The Cheshire is a great stay. Convenient location, great staff, yummy breakfast, free parking and all with so much character. What’s not to love? Ashley made our stay fun with all her energy and was always available with suggestions for yummy places to eat!"

Reviewed on Jun 12, 2026

Opens in a new windowThe Cheshire
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $199 total per night from Jun 28 to Jun 29
$199 total
Jun 28 - Jun 29
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (1,972 reviews)
"Great place to stay if youre seeing a show at the pageant"

Reviewed on Jun 9, 2026

Opens in a new windowMoonrise Hotel
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4 Star Hotels Roxana

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Roxana 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Roxana will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Roxana, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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