Explore top 2026 4 Star Hotels in Roxana

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Top Roxana 4 Star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $117 total per night from Mar 9 to Mar 10
$117 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,236 reviews)
Zero complaints! Enjoyed our stay and will stay again!

Reviewed on Feb 15, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Feb 27 to Feb 28
$176 total
Feb 27 - Feb 28
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.4/10 Very Good! (4,013 reviews)
The first room we got was not the cleanliest and was really rundown. So we called down to the front desk and got a second room, which was much better and you could tell was remodeled in the bathroom. Smelled clean, looked clean unlike first room.

Reviewed on Feb 11, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 24 to Feb 25
$162 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,602 reviews)
Everything was superlative. Staff, hotel, room, pool.

Reviewed on Feb 11, 2026

Opens in a new window21C Museum Hotel St Louis
The Cheshire

The Cheshire

4 out of 5
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $182 total per night from Feb 18 to Feb 19
$182 total
Feb 18 - Feb 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.6/10 Excellent! (1,001 reviews)
The theme of the entire hotel is wonderful. The staff is fantastic. The Fox and Hound Tavern is the most quaint aesthetics ever! Breakfastvis great. Clean rooms. Loved the themed rooms and read a little of the book portraying our themed lady of the court! Great place to stay!

Reviewed on Feb 7, 2026

Opens in a new windowThe Cheshire
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Feb 27 to Feb 28
$138 total
Feb 27 - Feb 28
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,064 reviews)
Everything was excellent.

Reviewed on Feb 3, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $141 total per night from Feb 22 to Feb 23
$141 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,051 reviews)
Very clean, even friendlier.

Reviewed on Feb 12, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Feb 17 to Feb 18
$177 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (1,120 reviews)
Everything was 10 star

Reviewed on Feb 14, 2026

Opens in a new windowLive by Loews - St.Louis
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Feb 22 to Feb 23
$148 total
Feb 22 - Feb 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,001 reviews)
The room was amazing! Very spacious & the beds were very comfortable. The bathtub was perfect for soaking after a long day of sports. Let’s all talk about Orlando…the best valet/staff member there. He was so friendly & helpful. We will for sure be staying here again.

Reviewed on Feb 11, 2026

Opens in a new windowThe Westin St. Louis
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Feb 23 to Feb 24
$154 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
8.2/10 Very Good! (1,002 reviews)
Clean, quiet, and the staff were great

Reviewed on Feb 6, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Forest Park
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $229 total per night from Feb 26 to Feb 27
$229 total
Feb 26 - Feb 27
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
8.4/10 Very Good! (1,007 reviews)
There is so much to do in this little spot. So much history to walk around and look at inside the hotel and outside.

Reviewed on Feb 12, 2026

Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
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4 Star Hotels Roxana

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Roxana 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Roxana will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Roxana, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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