Explore top 2025 4 Star Hotels in Jeffersonville - Clarksville

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Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $197 total per night from Sep 28 to Sep 29
$197 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $234 total per night from Sep 21 to Sep 22
$234 total
Sep 21 - Sep 22
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Omni Louisville Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $209 total per night from Sep 28 to Sep 29
$209 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...
Embassy Suites Louisville Downtown
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd, Louisville, KY
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Sep 8 to Sep 9
$140 total
Sep 8 - Sep 9
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
Derby City Gaming & Hotel - A Churchill Downs Property
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $168 total per night from Sep 8 to Sep 9
$168 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Hyatt Regency Louisville
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway, Louisville, KY
Fully refundableReserve now, pay when you stay
$181 nightly
The price is $213 total per night from Sep 8 to Sep 9
$213 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
The Brown Hotel
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $216 total per night from Sep 28 to Sep 29
$216 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
21c Museum Hotel Louisville
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St, Louisville, KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Sep 9 to Sep 10
$159 total
Sep 9 - Sep 10
Total with taxes and fees
This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
Hotel Genevieve part of JdV by Hyatt
Marriott Louisville East

Marriott Louisville East

4 out of 5
1903 Embassy Square Blvd, Louisville, KY
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $131 total per night from Sep 28 to Sep 29
$131 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Marriott Louisville East
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street, Louisville, KY
$212 nightly
The price is $249 total per night from Sep 28 to Sep 29
$249 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Louisville Marriott Downtown
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4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.