Explore top 2026 4 Star Hotels in Jeffersonville - Clarksville

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $166 total per night from May 25 to May 26
$166 total
May 25 - May 26
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,228 reviews)
Grart

Reviewed on May 11, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from May 17 to May 18
$133 total
May 17 - May 18
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (2,066 reviews)
Spacious, clean, comfortable, and very lovely accommodations. We will return.

Reviewed on May 11, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $293 total per night from May 22 to May 23
$293 total
May 22 - May 23
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.4/10 Exceptional! (1,882 reviews)
Everything about this property is amazing

Reviewed on May 10, 2026

Opens in a new windowOmni Louisville Hotel
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $192 total per night from May 26 to May 27
$192 total
May 26 - May 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,204 reviews)
This was a beautiful hotel! Very friendly staff! Had a great time there!

Reviewed on May 11, 2026

Opens in a new windowThe Brown Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $131 total per night from May 26 to May 27
$131 total
May 26 - May 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,229 reviews)
We had a King suite for 3 of us and planned to use the pull out bed. We got in late (wee hrs of the morning) and had to call to get linens for the bed. As we finally settled in, we pull back the bed of the king to get in and there were 2 hairs that appeared to be pubs. We were so exhausted at that ...

Reviewed on May 11, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from May 23 to May 24
$140 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,009 reviews)
I loved the 24/7 market!! Had self scan so it could be open all the time.

Reviewed on May 10, 2026

Opens in a new windowHyatt Regency Louisville
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $199 total per night from May 24 to May 25
$199 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,007 reviews)
👍

Reviewed on May 10, 2026

Opens in a new windowLouisville Marriott Downtown
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from May 17 to May 18
$159 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,085 reviews)
Only complaint is there is not enough light in the room

Reviewed on May 7, 2026

Opens in a new windowHotel Genevieve part of JdV by Hyatt
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $204 total per night from May 31 to Jun 1
$204 total
May 31 - Jun 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,006 reviews)
Located downtown next to all the great places to visit and eat. You can't go wrong staying here, the staff is wonderful and the food is great.

Reviewed on May 8, 2026

Opens in a new window21c Museum Hotel Louisville
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4 out of 5
101 West Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $206 total per night from May 25 to May 26
$206 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.6/10 Exceptional! (466 reviews)
Was put in a handicapped accessible room. Stay was average. Could have stayed in many neighboring hotels for much less

Reviewed on May 9, 2026

Opens in a new windowHotel Distil, Autograph Collection
Don't see what you're looking for?
See all available properties in Jeffersonville - Clarksville
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Jeffersonville - Clarksville hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity