Explore top 2026 4 Star Hotels in Jeffersonville - Clarksville

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $175 total per night from Mar 22 to Mar 23
$175 total
Mar 22 - Mar 23
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,083 reviews)
The carpet in the room needed vacuuming

Reviewed on Feb 19, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $234 total per night from Mar 19 to Mar 20
$234 total
Mar 19 - Mar 20
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,777 reviews)
Friendly, and very warm Staff!

Reviewed on Feb 19, 2026

Opens in a new windowOmni Louisville Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $135 total per night from Mar 8 to Mar 9
$135 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,162 reviews)
Very clean and quiet. The free drinks were also a plus.

Reviewed on Feb 17, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from Feb 22 to Feb 23
$133 total
Feb 22 - Feb 23
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (1,834 reviews)
The bed was terrible. There were huge sink holes in the mattress. Stayed on the second floor and the view from the window was literally the air conditioning units. I asked twice for fresh towels and never got any. There was loud music from a band easily heard in the room and was told they would be ...

Reviewed on Feb 20, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $210 total per night from Mar 19 to Mar 20
$210 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,197 reviews)
Beautiful old hotel I loved the decor and was very clean well taken care of!

Reviewed on Feb 19, 2026

Opens in a new windowThe Brown Hotel
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Feb 26 to Feb 27
$159 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,041 reviews)
Cute boutique in the heart of LGBTQ community of Nulu. Everything is in walking distance to food and bars.

Reviewed on Feb 16, 2026

Opens in a new windowHotel Genevieve part of JdV by Hyatt
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $216 total per night from Mar 9 to Mar 10
$216 total
Mar 9 - Mar 10
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,000 reviews)
Room was clean. The staff is helpful, nice, welcoming. Loved the art. Room is large. Great area.

Reviewed on Feb 15, 2026

Opens in a new window21c Museum Hotel Louisville
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Mar 21 to Mar 22
$169 total
Mar 21 - Mar 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,002 reviews)
everything was dirty, mystery stains and crumbs everywhere. they tried moving us rooms, and the new room was the same. elevator barely even worked. had to cancel our reservation and go elsewhere almost immediately. very much seems like the kind of place that puts on airs of luxury. would not ...

Reviewed on Feb 18, 2026

Opens in a new windowHyatt Regency Louisville
Marriott Louisville East

Marriott Louisville East

4 out of 5
1903 Embassy Square Blvd Louisville KY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Mar 1 to Mar 2
$149 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,000 reviews)
Staff was super sweet.

Reviewed on Feb 16, 2026

Opens in a new windowMarriott Louisville East
The Grady

The Grady

4 out of 5
601 W Main St Louisville KY
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $229 total per night from Feb 22 to Feb 23
$229 total
Feb 22 - Feb 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.
9.4/10 Exceptional! (1,004 reviews)
Clean room. Pleasant employees. No issues, but nothing really stood out. Certainly nothing bad - but nothing exceptional either. I would certainly stay again. The restaurant charge me $10.00 - plus tip - for 2 plain cups of coffee. I'm still thinking about that ... paying $5.00 for a cup of black ...

Reviewed on Feb 19, 2026

Opens in a new windowThe Grady
Don't see what you're looking for?
See all available properties in Jeffersonville - Clarksville
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Jeffersonville - Clarksville hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity