Explore top 2026 4 Star Hotels in Greenville

Name: The Grady
Price range: $211 total
Rating: 9.4

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Top Greenville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$147 nightly

$173 total

Apr 3 - Apr 4

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9/10 Wonderful! (4,089 reviews)

It was fine.

Reviewed on Mar 24, 2026

Derby City Gaming & Hotel - A Churchill Downs Property

4520 Poplar Level Rd Louisville KY

Fully refundableReserve now, pay when you stay

$113 nightly

$133 total

Mar 29 - Mar 30

Total with taxes and fees

This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...

9.4/10 Exceptional! (1,905 reviews)

Reviewed on Mar 24, 2026

Embassy Suites Louisville Downtown

501 South Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$115 nightly

$135 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...

9/10 Wonderful! (1,175 reviews)

Terrible.

Reviewed on Mar 23, 2026

The Brown Hotel

335 W Broadway Louisville KY

Fully refundableReserve now, pay when you stay

$178 nightly

$210 total

Apr 2 - Apr 3

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.4/10 Exceptional! (1,181 reviews)

Staff is amazing!!!

Reviewed on Mar 24, 2026

Hotel Genevieve part of JdV by Hyatt

730 E Market St Louisville KY

Fully refundableReserve now, pay when you stay

$135 nightly

$159 total

Mar 31 - Apr 1

Total with taxes and fees

This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.

9.2/10 Wonderful! (1,063 reviews)

We stayed in 4 hotels during a cross country trip and this was by far the best. I'm an interior designer and the decor made me silly happy. Every detail was well thought and executed and there were such cute amazing little surprises in every corner. The staff was friendly and accommodating and I ...

Reviewed on Mar 19, 2026

Louisville Marriott Downtown

280 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$168 nightly

$197 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,002 reviews)

Was clean and the staff was great !

Reviewed on Mar 25, 2026

21c Museum Hotel Louisville

700 W Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$183 nightly

$216 total

Mar 31 - Apr 1

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,000 reviews)

Great staff and a wonderful lobby experience. Room was spacious and clean. Restaurant and bar were both very good.

Reviewed on Mar 19, 2026

Hyatt Regency Louisville

320 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$129 nightly

$152 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.8/10 Excellent! (1,001 reviews)

The hotel overall was a disappointment this time around. Room was not cleaned all the way through small papers on the floor and other small objects on the couch. Woke up early to loud music at 6am and construction/remodeling banging shortly followed.

Reviewed on Mar 10, 2026

Hotel Distil, Autograph Collection

101 West Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$175 nightly

$206 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.6/10 Exceptional! (456 reviews)

Great location

Reviewed on Mar 8, 2026

The Grady

601 W Main St Louisville KY

Fully refundableReserve now, pay when you stay

$179 nightly

$211 total

Apr 1 - Apr 2

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

9.4/10 Exceptional! (1,002 reviews)

Perfect stay

Reviewed on Mar 25, 2026

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4 Star Hotels Greenville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.