Explore top 2026 4 Star Hotels in Greenville
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Top Greenville 4 Star hotels
Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $168 total per night from May 24 to May 25
$168 total
May 24 - May 25
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,222 reviews)
We needed to leave a day early and they wouldn’t refund me for the one day, after we paid for 7 days. I was very disappointed with that.
Reviewed on May 10, 2026
Derby City Gaming & Hotel - A Churchill Downs Property
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from May 17 to May 18
$133 total
May 17 - May 18
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (2,064 reviews)
Room was clean , friendly staff.
Reviewed on May 9, 2026
Omni Louisville Hotel
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $293 total per night from May 22 to May 23
$293 total
May 22 - May 23
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.4/10 Exceptional! (1,879 reviews)
Your staff was very knowledgeable and helpful
Reviewed on May 9, 2026
The Brown Hotel
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $192 total per night from May 26 to May 27
$192 total
May 26 - May 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,198 reviews)
Beautiful hotel with antique decor that harkens back to its founding in the 1920’s. The beds could be a little more comfortable.
Reviewed on May 10, 2026
Embassy Suites Louisville Downtown
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from May 25 to May 26
$126 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,221 reviews)
Breakfast was great--, staff needed to clean rooms more often
Reviewed on May 9, 2026
Hyatt Regency Louisville
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from May 23 to May 24
$140 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,007 reviews)
Great place overall, just disappointed with the check-in process. It took a very long time, and multiple guests in other lines were checked in or helped with their issues before I was ever assisted. Once checked in everything was great, but the arrival experience definitely needs improvement.
Reviewed on May 9, 2026
Louisville Marriott Downtown
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $199 total per night from May 24 to May 25
$199 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,005 reviews)
The television wasn’t working and even though I called twice it was not repaired until the last night of our 3 night stay.
Reviewed on May 1, 2026
Hotel Genevieve part of JdV by Hyatt
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from May 17 to May 18
$159 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,085 reviews)
Only complaint is there is not enough light in the room
Reviewed on May 7, 2026
21c Museum Hotel Louisville
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $204 total per night from May 31 to Jun 1
$204 total
May 31 - Jun 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,006 reviews)
Located downtown next to all the great places to visit and eat. You can't go wrong staying here, the staff is wonderful and the food is great.
Reviewed on May 8, 2026
Hotel Distil, Autograph Collection
101 West Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $206 total per night from May 25 to May 26
$206 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.6/10 Exceptional! (466 reviews)
Was put in a handicapped accessible room. Stay was average. Could have stayed in many neighboring hotels for much less
Reviewed on May 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Greenville
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Greenville hotel reviews by fellow wanderers
Galt House Hotel Trademark Collection by Wyndham
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"We needed to leave a day early and they wouldn’t refund me for the one day, after we paid for 7 days. I was very disappointed with that."
A verified traveler stayed at Galt House Hotel Trademark Collection by Wyndham
