Explore top 2026 4 Star Hotels in Greenville
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Top Greenville 4 Star hotels
Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $168 total per night from Aug 18 to Aug 19
$168 total
Aug 18 - Aug 19
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,251 reviews)
"The roof top pool and the sitting area all along the lobby was beautiful! Great place to gather with family and friends. Something that was really inconvenient and shocking was that there was only one and I mean ONE microwave not the lobby for a hotel that goes up to 22 or such floors and has two ..."
Reviewed on Aug 9, 2026
Omni Louisville Hotel
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $187 total per night from Aug 16 to Aug 17
$187 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.4/10 Exceptional! (2,070 reviews)
"Enjoyed the Mokara spa the rooftop pool and the amazing dining options available valet parking doesn't do In-N-Out parking so we found a nice lot called the Smith lot right across the street that allowed us to park for $7 a day in and out privileges were available"
Reviewed on Aug 8, 2026
Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from Aug 10 to Aug 11
$133 total
Aug 10 - Aug 11
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (2,418 reviews)
"Great place cleans and friendly staff."
Reviewed on Aug 8, 2026
Hyatt Regency Louisville
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $160 total per night from Aug 20 to Aug 21
$160 total
Aug 20 - Aug 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,009 reviews)
"Such a great stay. Thank you Hyatt Louisville!!!"
Reviewed on Aug 8, 2026
The Brown Hotel
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $184 total per night from Aug 20 to Aug 21
$184 total
Aug 20 - Aug 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,286 reviews)
"The restaurants and bar had outstanding service and delicious food. All hotel staff we encountered were friendly and helpful. The beautiful historic lobby is so nice to enjoy. The location is very convenient for The Palace."
Reviewed on Aug 7, 2026
Embassy Suites Louisville Downtown
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $151 total per night from Sep 5 to Sep 6
$151 total
Sep 5 - Sep 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,322 reviews)
"Absolutely loved everything about this hotel."
Reviewed on Aug 7, 2026
21c Museum Hotel Louisville
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $184 total per night from Sep 4 to Sep 5
$184 total
Sep 4 - Sep 5
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,014 reviews)
"I loved how eclectic this hotel was. The museums and all of the artwork were amazing. The moving penguins kept us laughing. We had an issue with our truck and the Valet was so helpful. We loved our nightly nightcap. We will definitely stay here again, and recommend it to others."
Reviewed on Aug 8, 2026
Hotel Genevieve part of JdV by Hyatt
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Aug 16 to Aug 17
$159 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
The Grady
601 W Main St Louisville KY
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $215 total per night from Aug 30 to Aug 31
$215 total
Aug 30 - Aug 31
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.
9.4/10 Exceptional! (1,007 reviews)
"Great location, very quiet and peaceful"
Reviewed on Aug 8, 2026
Louisville Marriott Downtown
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $201 total per night from Sep 4 to Sep 5
$201 total
Sep 4 - Sep 5
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,000 reviews)
"The drinks were amazing, the staff were friendly and attentive. Great location."
Reviewed on Aug 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Greenville
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Greenville hotel reviews by fellow wanderers
Homewood Suites by Hilton Louisville Downtown, KY
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Great location just a few blocks from Whiskey Row. Rooms were clean and large. Very nice to have breakfast included daily as well. Would definitely stay here again!"
A verified traveler stayed at Homewood Suites by Hilton Louisville Downtown, KY
