Explore top 2025 4 Star Hotels in West Main Historic District
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Top West Main Historic District 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $110 total per night from Nov 26 to Nov 27
$110 total
Nov 26 - Nov 27
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.8/10 Excellent! (3,774 reviews)
Clean room
Reviewed on Nov 16, 2025

Omni Louisville Hotel
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $234 total per night from Dec 5 to Dec 6
$234 total
Dec 5 - Dec 6
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,688 reviews)
The Omni was fantastic. Clean and comfortable rooms. Friendly staff and close to everything
Reviewed on Nov 18, 2025

Embassy Suites Louisville Downtown
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $132 total per night from Nov 30 to Dec 1
$132 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...
8.8/10 Excellent! (1,081 reviews)
The stay was great except for the hallway on the 4th floor smelled like baby poop. We could not smell the odor in our room. The hotel staff did address our concern and the smell was lessened.
Reviewed on Nov 20, 2025

Derby City Gaming & Hotel - A Churchill Downs Property
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Nov 23 to Nov 24
$140 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (1,621 reviews)
Once again, Derby City Gaming and hotel does not disappoint. Great casino and hotel!!! Highly recommend!
Reviewed on Nov 21, 2025

The Brown Hotel
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $139 total per night from Nov 23 to Nov 24
$139 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.2/10 Wonderful! (1,120 reviews)
It was clean just very old and dated. Area around hotel was just ok. Breakfast was super expensive. Bars were good.
Reviewed on Nov 20, 2025

Hotel Genevieve part of JdV by Hyatt
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Nov 24 to Nov 25
$159 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,007 reviews)
Should have two vanities but otherwise great
Reviewed on Nov 18, 2025

21c Museum Hotel Louisville
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $216 total per night from Nov 23 to Nov 24
$216 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,003 reviews)
Great location, street parking, art gallery, welcome bourbon tasting at the bar
Reviewed on Nov 21, 2025

Hyatt Regency Louisville
320 West Jefferson Street Louisville KY
$99 nightly
The price is $117 total per night from Nov 27 to Nov 28
$117 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.6/10 Excellent! (1,006 reviews)
Staff very friendly and room was clean. You had to swipe your key for the floor you were going to
Reviewed on Nov 17, 2025

Marriott Louisville East
1903 Embassy Square Blvd Louisville KY
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $129 total per night from Nov 28 to Nov 29
$129 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,004 reviews)
Very nice hotel, rooms were clean and comfortable, breakfast is great!
Reviewed on Nov 15, 2025

The Grady
601 W Main St Louisville KY
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $172 total per night from Nov 23 to Nov 24
$172 total
Nov 23 - Nov 24
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.
9.2/10 Wonderful! (1,001 reviews)
Nice hotel in a nice location, but not worth the cost.
Reviewed on Nov 13, 2025
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Recent West Main Historic District hotel reviews by fellow wanderers

21c Museum Hotel Louisville
5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"Great location, street parking, art gallery, welcome bourbon tasting at the bar
"
A verified traveler stayed at 21c Museum Hotel Louisville
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