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Top hotels in South Main

The Peabody Memphis

The Peabody Memphis

5 out of 5
149 Union Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $262 total per night from Nov 22 to Nov 23
$262 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
"The Peabody was wonderful. The only complaint I have was"

Reviewed on Nov 11, 2026

Opens in a new windowThe Peabody Memphis
Big Cypress Lodge

Big Cypress Lodge

5 out of 5
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$242 nightly
The price is $289 total per night from Dec 6 to Dec 7
$289 total
Dec 6 - Dec 7
Total with taxes and fees
This luxury hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Valet parking, a 24-hour business center, and a terrace ...
"This place is amazing"

Reviewed on Nov 10, 2026

Opens in a new windowBig Cypress Lodge
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $139 total per night from Dec 1 to Dec 2
$139 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Self parking, ...
"Great location and price. Parking is in lot across street, and is added cost. Otherwise, room was nice and clean, and being in an older, well built building, very quiet. Convenient to all downtown sights and spots, and an easy walk to Mud Island Park for the pups. Does have a nightclub on the roof, ..."

Reviewed on Nov 11, 2026

Opens in a new windowHu. Hotel
Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites

2.5 out of 5
8635 Us Highway 64 Memphis TN
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $90 total per night from Dec 6 to Dec 7
$90 total
Dec 6 - Dec 7
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. ...
"Biggest issue was actually with the Expedia reservation process - first time I booked it listed two travelers (I travel solo) and billed me double for the insurance. Only way to fix that was to cancel and rebook. Second booking apparently downgraded the room to the smallest one in the hotel. Front ..."

Reviewed on Nov 10, 2026

Opens in a new windowBest Western Plus Galleria Inn & Suites
ARRIVE Memphis

ARRIVE Memphis

4 out of 5
477 S Main St Memphis TN
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $180 total per night from Nov 15 to Nov 16
$180 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
Opens in a new windowARRIVE Memphis
The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton

4 out of 5
545 South Main Memphis TN
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $147 total per night from Nov 22 to Nov 23
$147 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowThe Central Station Memphis, Curio Collection by Hilton
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4 out of 5
33 BEALE STREET Memphis TN
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $181 total per night from Nov 26 to Nov 27
$181 total
Nov 26 - Nov 27
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet ...
Opens in a new windowHyatt Centric Beale Street Memphis
The Guest House at Graceland

The Guest House at Graceland

4 out of 5
3600 Elvis Presley Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$219 nightly
The price is $266 total per night from Nov 16 to Nov 17
$266 total
Nov 16 - Nov 17
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, laundry service, and free ...
Opens in a new windowThe Guest House at Graceland
Memphis Riverline Hotel

Memphis Riverline Hotel

4 out of 5
250 N Main St Memphis TN
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $224 total per night from Nov 20 to Nov 21
$224 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Opens in a new windowMemphis Riverline Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Main Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on South Main area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near South Main to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near South Main are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent South Main hotel reviews by fellow wanderers

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