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Top hotels in Medical District

The Peabody Memphis

The Peabody Memphis

3.5 out of 5
149 Union Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$190 nightly
The price is $238 total per night from Apr 4 to Apr 5
$238 total
Apr 4 - Apr 5
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this historic hotel. Traveling on business? Take advantage of the business center, free WiFi ...
2 hours to get our room after 4 pm check in time

Reviewed on Mar 22, 2026

Opens in a new windowThe Peabody Memphis
Big Cypress Lodge

Big Cypress Lodge

5 out of 5
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $343 total per night from Apr 13 to Apr 14
$343 total
Apr 13 - Apr 14
Total with taxes and fees
This luxury hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Valet parking, a 24-hour business center, and a terrace ...
We have stayed here multiple times and Always enjoy it!

Reviewed on Mar 19, 2026

Opens in a new windowBig Cypress Lodge
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4 out of 5
33 BEALE STREET Memphis TN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $182 total per night from Apr 5 to Apr 6
$182 total
Apr 5 - Apr 6
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet ...
There was a glass of white wine in our room from the prior guest, which had not been removed by housekeeping. We tried to valet park, but they told us to park ourselves and come back later and bring us there car if we wanted to valet. Why would anyone park themselves and then bring the car back later ...

Reviewed on Mar 22, 2026

Opens in a new windowHyatt Centric Beale Street Memphis
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

2.5 out of 5
100 N Front St Memphis TN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $132 total per night from Apr 20 to Apr 21
$132 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Pros: hotel location, breakfast and staff Cons: paper thin walls and slamming of doors a lot.

Reviewed on Mar 23, 2026

Opens in a new windowComfort Inn Memphis Downtown
Aloft Memphis Downtown

Aloft Memphis Downtown

3 out of 5
63 N. B. B. King Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $124 total per night from Mar 29 to Mar 30
$124 total
Mar 29 - Mar 30
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking is offered and the front desk is staffed ...
Nice hotel and convenient location

Reviewed on Mar 22, 2026

Opens in a new windowAloft Memphis Downtown
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $135 total per night from Mar 29 to Mar 30
$135 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Self parking, ...
Wonderful and pleasant staff. Special shout out to Ebony at the front desk for being cordial with every guest and Gena at the rooftop bar. Every hotel staff member was kind and helpful.

Reviewed on Mar 23, 2026

Opens in a new windowHu. Hotel
Memphis Vitality Hotel

Memphis Vitality Hotel

4 out of 5
2625 Thousand Oaks Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $125 total per night from Mar 31 to Apr 1
$125 total
Mar 31 - Apr 1
Total with taxes and fees
This hotel features an outdoor pool, an indoor pool, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the 24-hour ...
1 elevator worked. they opened the service elevator which apparently can only stop on certain floors or else it gets stuck, the lights in the rooms are so low you may as well be blind. i didnt receive checkin instructions til an hour before time ( with the wrong days listed on it) despite a text ...

Reviewed on Mar 23, 2026

Opens in a new windowMemphis Vitality Hotel
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

3 out of 5
2979 Millbranch Road Memphis TN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $87 total per night from Mar 30 to Mar 31
$87 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Traveling on business? Take ...
airport shuttle great

Reviewed on Mar 22, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Memphis Airport Graceland
Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from Mar 24 to Mar 25
$65 total
Mar 24 - Mar 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli and laundry facilities are also provided.
No access to lobby, had to check in thru a drive thru type window. Made the mistake on walking on floor in room barefoot and my feet were black in a few minutes. Spend the extra money and stay somewhere else.

Reviewed on Mar 23, 2026

Opens in a new windowMotel 6 Memphis, TN - Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Medical District hotel reviews by fellow wanderers

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

4 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Pros: hotel location, breakfast and staff Cons: paper thin walls and slamming of doors a lot."
A verified traveler stayed at Comfort Inn Memphis Downtown
Comfort Inn Memphis Downtown

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