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Top hotels in Medical District

The Guest House at Graceland

The Guest House at Graceland

4 out of 5
3600 Elvis Presley Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$194 nightly
The price is $236 total per night from Apr 29 to Apr 30
$236 total
Apr 29 - Apr 30
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, laundry service, and free ...
This hotel is gorgeous and an Elboc lovers paradise! It is really close to Gracelands and the hotel supplies free shuttle buses there and to the airport. The rooms are beautiful and great size. All the staff are very polite and helpful. Amore expensive than other hotels available but if you’re looking ...

Reviewed on Apr 23, 2026

Opens in a new windowThe Guest House at Graceland
The Peabody Memphis

The Peabody Memphis

3.5 out of 5
149 Union Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$190 nightly
The price is $238 total per night from May 18 to May 19
$238 total
May 18 - May 19
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this historic hotel. Traveling on business? Take advantage of the business center, ...
Iconic old southern hotel - bucket list stay

Reviewed on Apr 23, 2026

Opens in a new windowThe Peabody Memphis
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4 out of 5
33 BEALE STREET Memphis TN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $182 total per night from May 24 to May 25
$182 total
May 24 - May 25
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet ...
Great hotel that was well located in the city to explore and have fun. Friendly staff, clean and well equipped rooms. It felt safe in the area and the rooms were quiet (well we were at the back of the property and they were). The rooftop bar was really great and the view of the bridge and Mississippi ...

Reviewed on Apr 23, 2026

Opens in a new windowHyatt Centric Beale Street Memphis
Big Cypress Lodge

Big Cypress Lodge

5 out of 5
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$252 nightly
The price is $301 total per night from Apr 30 to May 1
$301 total
Apr 30 - May 1
Total with taxes and fees
This luxury hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Valet parking, a 24-hour business center, and a terrace ...
We really did enjoy our stay overall, but I want to leave some information that may be helpful. We would go back, but maybe when there is more happening at the resort. Pros: all staff was friendly, beds were comfortable, in-room jacuzzi was nice, we had plenty of towels, complimentary bottled water ...

Reviewed on Apr 22, 2026

Opens in a new windowBig Cypress Lodge
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

2.5 out of 5
100 N Front St Memphis TN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $132 total per night from May 20 to May 21
$132 total
May 20 - May 21
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Parking was easy and breakfast was good. There was no hot water in the mornings either morning. Learned to shower at night. There was a train that came by at 6:15 every morning.

Reviewed on Apr 23, 2026

Opens in a new windowComfort Inn Memphis Downtown
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $115 total per night from May 3 to May 4
$115 total
May 3 - May 4
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Self parking, ...
Roz the desk receptionist went out of her way to make us comfortable during our one night stay. She recommended a Bbq restaurant within walking distance. It was soo good. Our room was conveniently located to the elevator and morning fabulous full hot breakfast. Parking garage was located directly ...

Reviewed on Apr 23, 2026

Opens in a new windowHu. Hotel
Memphis Riverline Hotel

Memphis Riverline Hotel

4 out of 5
250 N Main St Memphis TN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $156 total per night from May 10 to May 11
$156 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Our room was clean, but some things were not present: tissue paper, hair dryer, privacy sign, downstairs menu, WiFi instructions. The landline telephone basically worked, but the direct line buttons, i.e., Guest Services, Emergency, etc., did nothing when pressed.

Reviewed on Apr 21, 2026

Opens in a new windowMemphis Riverline Hotel
Kings Inn

Kings Inn

2 out of 5
42 S Camilla St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from May 13 to May 14
$65 total
May 13 - May 14
Total with taxes and fees
This hotel features a convenience store, laundry facilities, and free self parking. Express check-out is provided and the front desk is staffed ...
It's nasty and they have poor night staff service there's bullet holes in the doors and prostitution is allowed

Reviewed on Apr 23, 2026

Opens in a new windowKings Inn
Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from Apr 24 to Apr 25
$65 total
Apr 24 - Apr 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli and laundry facilities are also provided.
Room smelled of smoke, i adled for non smoking. There were burn marks throughout the comforter and covers and pillows had stains. Moved to a second room. Suppose to been non smoking, also reeked of cigarette smoked. I brought febreze. Also burn stains and marks throughtout room. Their was a roach ...

Reviewed on Apr 23, 2026

Opens in a new windowMotel 6 Memphis, TN - Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Medical District hotel reviews by fellow wanderers

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