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Top hotels in Medical District

The Guest House at Graceland

The Guest House at Graceland

4 out of 5
3600 Elvis Presley Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$194 nightly
The price is $236 total per night from May 18 to May 19
$236 total
May 18 - May 19
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, laundry service, and free ...
The outside needs to be kept more clean. Outside by the pool, the fire pits are seldom lit because there’s no gas & no one keeps the propane full. The staff & valet are fantastic!!!!

Reviewed on Apr 28, 2026

Opens in a new windowThe Guest House at Graceland
The Peabody Memphis

The Peabody Memphis

3.5 out of 5
149 Union Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$190 nightly
The price is $238 total per night from May 17 to May 18
$238 total
May 17 - May 18
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this historic hotel. Traveling on business? Take advantage of the business center, ...
We enjoyed our stay, but our breakfast

Reviewed on Apr 28, 2026

Opens in a new windowThe Peabody Memphis
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4 out of 5
33 BEALE STREET Memphis TN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $182 total per night from May 24 to May 25
$182 total
May 24 - May 25
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet ...
Friendly staff, nice hotel.

Reviewed on Apr 28, 2026

Opens in a new windowHyatt Centric Beale Street Memphis
Big Cypress Lodge

Big Cypress Lodge

5 out of 5
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$256 nightly
The price is $306 total per night from Apr 30 to May 1
$306 total
Apr 30 - May 1
Total with taxes and fees
This luxury hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Valet parking, a 24-hour business center, and a terrace ...
Amazing experience definitely would stay again

Reviewed on Apr 27, 2026

Opens in a new windowBig Cypress Lodge
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

2.5 out of 5
100 N Front St Memphis TN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $142 total per night from May 19 to May 20
$142 total
May 19 - May 20
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Enjoy breakfast and people

Reviewed on Apr 28, 2026

Opens in a new windowComfort Inn Memphis Downtown
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $112 total per night from May 28 to May 29
$112 total
May 28 - May 29
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Self parking, ...
We enjoyed our two nights a Hu. Hotel. The location is fantastic. For a downtown hotel the parking arrangement at a garage across the street is convenient (although expensive). The staff (and particularly the concierge Dedrick) were extremely welcoming and helpful. The rooms are spacious and nicely ...

Reviewed on Apr 28, 2026

Opens in a new windowHu. Hotel
Memphis Riverline Hotel

Memphis Riverline Hotel

4 out of 5
250 N Main St Memphis TN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $156 total per night from May 13 to May 14
$156 total
May 13 - May 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Everything was great, no price tags in the store and then paying $10 for a bottle of water seemed a little excessive.

Reviewed on Apr 28, 2026

Opens in a new windowMemphis Riverline Hotel
Kings Inn

Kings Inn

2 out of 5
42 S Camilla St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from May 10 to May 11
$65 total
May 10 - May 11
Total with taxes and fees
This hotel features a convenience store, laundry facilities, and free self parking. Express check-out is provided and the front desk is staffed ...
Awful smell full of modern roach motel

Reviewed on Apr 25, 2026

Opens in a new windowKings Inn
Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from Apr 30 to May 1
$65 total
Apr 30 - May 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli and laundry facilities are also provided.
The room was clean and well supplied. The property appears to be in a not very friendly neighborhood. The entire property is fenced and you need your key to enter the property every time. Has big signs explaining they are not responsible for damages or lost property in the parking lot. It is unease ...

Reviewed on Apr 27, 2026

Opens in a new windowMotel 6 Memphis, TN - Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Medical District hotel reviews by fellow wanderers

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Enjoy breakfast and people "
A verified traveler stayed at Comfort Inn Memphis Downtown
Comfort Inn Memphis Downtown

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