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Top hotels in Medical District

The Guest House at Graceland
"Horrible constriction messed up our tire in our vehicle the room A/C wasn’t working well the drawers in furniture get stuck. N maids need to be a little fire fly. The room was not worth what we paid n I think guest house needs to starts new repairs . We were charged for our breakfast twice as our ..."
Reviewed on Jun 3, 2026

The Peabody Memphis
"Beautiful hotel with a large lobby and live entertainment. We like the high quality restaurants on site. Comfortable beds and rooms, however bathrooms could be larger. No double sink or 2 person capacity in some rooms."
Reviewed on Jun 2, 2026

Hyatt Centric Beale Street Memphis
"Great hotel but very overpriced on food and drink."
Reviewed on Jun 3, 2026

Big Cypress Lodge
"I never give a perfect rating to hotels because I think there’s always room for improvement but Big Cypress Lodge has changed my mind. I have NEVER stayed at a property that was as friendly hospitable and welcoming as this place, and I have stayed at many Disney properties and high end hotels. The ..."
Reviewed on Jun 3, 2026

Comfort Inn Memphis Downtown
"Exceeded my expectations. Good rooms, VERY strong water pressure in the showers, a rooftop pool overlooking the Mississippi River. Great staff, warm full breakfast bar, and free parking."
Reviewed on Jun 3, 2026

Hu. Hotel
"Great location. Friendly customer service."
Reviewed on Jun 3, 2026

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
"Love the vibes always helpful when I fly in and out from Cali"
Reviewed on Jun 2, 2026

Motel 6 Memphis, TN - Downtown
"It was ok, kinds different . But ok"
Reviewed on Jun 2, 2026

Kings Inn
Medical District Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Medical District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical District to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Medical District hotel reviews by fellow wanderers

Big Cypress Lodge
"I never give a perfect rating to hotels because I think there’s always room for improvement but Big Cypress Lodge has changed my mind. I have NEVER stayed at a property that was as friendly hospitable and welcoming as this place, and I have stayed at many Disney properties and high end hotels. The way every single staff member we encountered was kind enthusiastic and wonderful to our 4 year old son & our dogs made this property worth every cent we spent to stay there and we will return."
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