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Top hotels in South Main

Hotel Pontotoc

Hotel Pontotoc

2 out of 5
69 E Pontotoc Ave Memphis TN
$263 nightly
The price is $313 total per night from Jan 18 to Jan 19
$313 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a bar/lounge, free WiFi in public areas, and dry cleaning. Enjoy the free on-the-go breakfast each morning. Luggage storage and a virtual ...
This was my second stay at this property and I enjoyed everything about it. The beds are exceptionally comfortable. The staff is easy to reach. The complimentary breakfast delivered to the room was a nice touch. The onsite bar is upscale and service was excellent. The location is very walkable and ...

Reviewed on Jan 4, 2026

Opens in a new windowHotel Pontotoc
ARRIVE Memphis

ARRIVE Memphis

4 out of 5
477 S Main St Memphis TN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $186 total per night from Feb 15 to Feb 16
$186 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
Love the arrive!

Reviewed on Jan 12, 2026

Opens in a new windowARRIVE Memphis
The Guest House at Graceland

The Guest House at Graceland

4 out of 5
3600 Elvis Presley Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$202 nightly
The price is $246 total per night from Feb 1 to Feb 2
$246 total
Feb 1 - Feb 2
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, laundry service, and free ...
Staff was fantastic.Room clean

Reviewed on Jan 13, 2026

Opens in a new windowThe Guest House at Graceland
Big Cypress Lodge

Big Cypress Lodge

5 out of 5
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$227 nightly
The price is $271 total per night from Feb 2 to Feb 3
$271 total
Feb 2 - Feb 3
Total with taxes and fees
This luxury hotel's 2 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Valet parking, a 24-hour business center, and a terrace ...
The room was amazing and comfortable. The staff was outstanding and greeted you with a smile and was very courteous and welcoming and outstanding service. I would definitely recommend to anyone to stay there and I definitely stay there again in the future.

Reviewed on Jan 11, 2026

Opens in a new windowBig Cypress Lodge
The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton

4 out of 5
545 South Main Memphis TN
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $157 total per night from Jan 30 to Jan 31
$157 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything and everyone was absolutely wonderful‼️Customer service was outstanding‼️

Reviewed on Jan 12, 2026

Opens in a new windowThe Central Station Memphis, Curio Collection by Hilton
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4 out of 5
33 BEALE STREET Memphis TN
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $161 total per night from Jan 25 to Jan 26
$161 total
Jan 25 - Jan 26
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet ...
clea

Reviewed on Jan 13, 2026

Opens in a new windowHyatt Centric Beale Street Memphis
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

2.5 out of 5
100 N Front St Memphis TN
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $135 total per night from Jan 19 to Jan 20
$135 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Rooms are excellent. Customer service was amazing and fast.

Reviewed on Jan 14, 2026

Opens in a new windowComfort Inn Memphis Downtown
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $115 total per night from Jan 23 to Jan 24
$115 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Self parking, ...
This was my 3rd stay at Hu. and will be the only place we stay whenever we’re in Memphis. Customer service is always wonderful-especially when the gentleman is there at the door. The rooms are always clean and welcoming and the location is perfect for us.

Reviewed on Jan 13, 2026

Opens in a new windowHu. Hotel
Memphis Vitality Hotel

Memphis Vitality Hotel

4 out of 5
2625 Thousand Oaks Blvd Memphis TN
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $107 total per night from Jan 18 to Jan 19
$107 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool, an indoor pool, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the 24-hour ...
Staff was phenomenal and made the experience amazing. Highly recommend this hotel and with easy access to the interstate this made it the perfect stay for anyone visiting Baptist memorial hospital. Additionally the restaurant served outstanding food and the bartender was extremely efficient and friendly. ...

Reviewed on Jan 11, 2026

Opens in a new windowMemphis Vitality Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Main Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on South Main area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near South Main to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near South Main are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent South Main hotel reviews by fellow wanderers

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Rooms are excellent. Customer service was amazing and fast."
A verified traveler stayed at Comfort Inn Memphis Downtown
Comfort Inn Memphis Downtown

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