Book Hotels in Santa Fe, FL
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Top Santa Fe hotels

Hotel Eleo at the University of Florida
1514 Southwest 14th Street Gainesville FL
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $143 total per night from Dec 4 to Dec 5
$143 total
Dec 4 - Dec 5
Total with taxes and fees
A restaurant and a gym are featured at this hotel. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
Don't like not being able to park our own car.
Reviewed on Nov 22, 2025

Comfort Suites Gainesville near University
2603 SW 13TH STREET Gainesville FL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Dec 9 to Dec 10
$100 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Clean rooms, quiet location. Close to Shands Hospital
Reviewed on Nov 20, 2025

La Quinta by Wyndham Gainesville
908 NW 69 Terrace Gainesville FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Nov 30 to Dec 1
$96 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was spotless and well prepared for us. The lobby was outstanding. I was able to conduct business in a relaxed manner in the main lobby. Very comfortable stay.
Reviewed on Nov 20, 2025

Country Inn & Suites by Radisson, Gainesville, FL
4015 Sw 43rd St Gainesville FL
Fully refundable
$93 nightly
The price is $105 total per night from Dec 16 to Dec 17
$105 total
Dec 16 - Dec 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Brooke was very helpful and did an excellent job checking us is
Reviewed on Nov 18, 2025

Sleep Inn & Suites University/Shands
4110 SW 40th Boulevard Gainesville FL
Fully refundable
$81 nightly
The price is $91 total per night from Dec 19 to Dec 20
$91 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The location was very good. The facility could use a very deep clean. The staff there was excellent.
Reviewed on Nov 23, 2025

Best Western Gateway Grand
4200 NW 97th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Dec 1 to Dec 2
$105 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
Very nice
Reviewed on Nov 21, 2025

HOM Hotel Gainesville, SureStay Collection by Best Western
3905 Sw 43Rd St Gainesville FL
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Dec 1 to Dec 2
$87 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Personnel were excellent room was cleaned everyday. Can't say enough good things. Inly one thing, I saw two roaches in the bathroom.
Reviewed on Nov 20, 2025

Comfort Inn University
3440 SW 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Dec 7 to Dec 8
$96 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Our one night stay was comfortable.
Reviewed on Nov 20, 2025

Red Roof Inn PLUS+ Gainesville
3500 Southwest 42nd St Gainesville FL
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Dec 7 to Dec 8
$74 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock ...
Good room but no breakfast options.
Reviewed on Nov 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Santa Fe hotel reviews by fellow wanderers

Hyatt Place Gainesville Downtown
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Breakfast was quite a large array of options. The staff was friendly and helpful. The hotel was very clean and the keycards, made it feel very safe. The pool area was clean, and the order to poolside was very convenient. The bar in the hotel, was clean, the bartender was very nice and suggested some amazing drinks. The maple bourbon smash was incredible. The noise machine and black out curtains made sleeping a dream! The only complaint, is in the rooms the vents were quite dirty, but everything else was cleaned to our standard! :)"
A verified traveler stayed at Hyatt Place Gainesville Downtown
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