Book Hotels in Santa Fe, FL
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Top Santa Fe hotels

Drury Inn & Suites Gainesville
4000 Southwest 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Apr 6 to Apr 7
$127 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Clean and friendly environment
Reviewed on Apr 2, 2026

Hotel Eleo at the University of Florida
1514 Southwest 14th Street Gainesville FL
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $182 total per night from Apr 5 to Apr 6
$182 total
Apr 5 - Apr 6
Total with taxes and fees
A restaurant and a gym are featured at this hotel. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
The clerk at the checkin desk was not very friendly.
Reviewed on Mar 26, 2026

Country Inn & Suites by Radisson, Gainesville, FL
4015 Sw 43rd St Gainesville FL
Fully refundable
$88 nightly
The price is $99 total per night from Apr 13 to Apr 14
$99 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Excelent
Reviewed on Apr 2, 2026

Hyatt Place Gainesville Downtown
212 SE 1ST STREET, Gainesville FL
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $143 total per night from Apr 12 to Apr 13
$143 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was perfect Nice location downtown to walk to restaurants
Reviewed on Mar 30, 2026

Hotel Indigo Gainesville-Celebration Pointe by IHG
5020 SW 30th Lane Gainesville FL
Fully refundable
$106 nightly
The price is $119 total per night from Apr 7 to Apr 8
$119 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great location if you go to the event center
Reviewed on Mar 29, 2026

Sleep Inn & Suites University/Shands
4110 SW 40th Boulevard Gainesville FL
Fully refundable
$85 nightly
The price is $96 total per night from Apr 8 to Apr 9
$96 total
Apr 8 - Apr 9
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The breakfast was very good, but the woman that was in the breakfast room arranging the food was extremely rude. She treated my 80 year old mother very bad. I complained to the front desk and they said many people have complained about her. I don't understand why the manager does not do anything ...
Reviewed on Apr 2, 2026

HOM Hotel Gainesville, SureStay Collection by Best Western
3905 Sw 43Rd St Gainesville FL
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Apr 8 to Apr 9
$87 total
Apr 8 - Apr 9
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Everything was great even the staff, room was very clean. 10/10
Reviewed on Apr 1, 2026

DoubleTree by Hilton Gainesville
3726 Sw 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Apr 12 to Apr 13
$109 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and free WiFi. A terrace, a garden, and a ...
The rooms were amazing—clean, comfortable, and well-maintained. The staff was also incredible—very friendly, helpful, and professional throughout my stay. The location is a major plus, as the hotel is surrounded by everything you need, making it very convenient. The only downside was parking. When ...
Reviewed on Apr 1, 2026

Red Roof Inn PLUS+ Gainesville
3500 Southwest 42nd St Gainesville FL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $82 total per night from Apr 9 to Apr 10
$82 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock ...
Air Conditioning works very well. My room was clean but needs repairs. The walls have what looks like severe past water damage.
Reviewed on Apr 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Fe hotel reviews by fellow wanderers

Hilton University of Florida Conference Center Gainesville
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The bed was cozy, the pillows were great. The room was quiet, and the air conditioner kept the room cool."
A verified traveler stayed at Hilton University of Florida Conference Center Gainesville
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