Find a Hotel in Midtown
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch
"We always enjoy and like to book at Drury properties. Easy check in. Was a very busy weekend in St. Louis yet staff were relaxed and friendly. Easy self parking 2 blocks away, breakfast very good and as always, Kickback was plentiful!"
Reviewed on Jun 20, 2026

Pear Tree Inn St. Louis Airport
"The room was clean and staff was very friendly. The breakfast was better than expected (biscuits, gravy, eggs, sausage patties, muffin bagels, bread, cereal, homemade waffles, yougurt, fruit) The A/C worked very well, however the unit leaked onto the carpet in front of the window. We immediately ..."
Reviewed on Jun 20, 2026

Element by Marriott St. Louis Midtown
"It was an awesome stay! Everyone was so friendly and clean. I wish the pool wasn't so cold though."
Reviewed on Jun 19, 2026

Clayton Plaza Hotel & Extended Stay
"Room was clean and the parking area is connected to the hotel which is very convenient. Breakfast is added bonus. The staff is great."
Reviewed on Jun 20, 2026

Pear Tree Inn St. Louis Near Union Station
"Great service. Clean rooms"
Reviewed on Jun 19, 2026

Hyatt Regency St. Louis at The Arch
"Rooms are clean, friendly staff, few steps to go to St Louis historic arch. Not all lifts were functional. there will a long wait for lifts on busy times."
Reviewed on Jun 19, 2026

Hollywood Casino & Hotel St. Louis
"I would stay again! It’s very convenient."
Reviewed on Jun 17, 2026

Residence Inn by Marriott St Louis Downtown
"This is probably the dirtiest place I’ve ever stayed. The floors were filthy. The couch had spots all over it and pulled out to a bed. The mattress was thin and had stains, and the pullout couch itself was broken. There is no soap, shampoo or conditioner in the showers we had to ask for more; we ..."
Reviewed on Jun 19, 2026

Forest Park Hotel by MDR
"There was a dirty sick between the bed and headboard, the sheets did not appear clean, and the lock on the balcony did not lock properly. The staff at check in and check out were both very nice."
Reviewed on Jun 20, 2026
Midtown Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Midtown hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Airport
"The room was clean and staff was very friendly. The breakfast was better than expected (biscuits, gravy, eggs, sausage patties, muffin bagels, bread, cereal, homemade waffles, yougurt, fruit) The A/C worked very well, however the unit leaked onto the carpet in front of the window. We immediately informed the staff, who told us we couldn't be moved because the hotel was booked, but as guests checked out the next day we could have a different room. We were ok with that, since the ac worked fine. My family and I spent the next day sight-seeing. We checked with the front desk upon returning and were informed that maintenance had checked and the AC was not leaking anymore, they were unsure why it had leaked at all. They claim to have attempted to contact us to change rooms, but were unable to reach us. They had no other rooms available. "
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