Find a Hotel in Midtown
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch
Reviewed on Sep 25, 2025

Pear Tree Inn St. Louis Airport
Reviewed on Sep 24, 2025

Element St. Louis Midtown
Reviewed on Sep 28, 2025

Clayton Plaza Hotel & Extended Stay
Reviewed on Sep 24, 2025

Pear Tree Inn St. Louis Near Union Station
Reviewed on Sep 24, 2025

Hyatt Regency St. Louis at The Arch
Reviewed on Sep 25, 2025

Renaissance St. Louis Airport Hotel
Reviewed on Sep 22, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Reviewed on Sep 24, 2025

Residence Inn by Marriott St Louis Downtown
Reviewed on Sep 28, 2025
Midtown Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Midtown hotel reviews by fellow wanderers

Residence Inn by Marriott St Louis Downtown
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