Find a Hotel in Midtown
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch
"Fabulous location. Right behind the arch and a block from the ballpark."
Reviewed on Jun 29, 2026

Pear Tree Inn St. Louis Airport
"everyone always helpful"
Reviewed on Jun 28, 2026

Element by Marriott St. Louis Midtown
"clean and nice"
Reviewed on Jun 28, 2026

Moonrise Hotel
"Room was fantastic. Loved the theme. Bathroom was very modern. Only thing to keep in mind is the rooftop bar has club music on the weekends. We were on the 7th floor right underneath it so that was kind of loud. Not a huge deal as it closed at 1230am. Overall really nice place with tons of attractions ..."
Reviewed on Jun 29, 2026

Clayton Plaza Hotel & Extended Stay
"Enjoyed our stay."
Reviewed on Jun 29, 2026

Hyatt Regency St. Louis at The Arch
"It was convenient and located right at the St Louis Arch which we visited. It didn't have a lot of food places. We had to walk far to get to our room. We had to pay extra for valet parking because the self-parking garage was full. But it was a great old hotel for the price we paid."
Reviewed on Jun 29, 2026

Residence Inn by Marriott St Louis Downtown
"Evening desk needs a better understanding of English to avoid misunderstandings. Two early morning awakenings by fire alarms, one after the other, not recommended for good rest. Morning staff was very friendly and helpful with improving my stay."
Reviewed on Jun 27, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"Breakfast was eh. Very minimal for hot breakfast. Room was nice. Thermostat didn't go below 66. Ac unit was loud so falling asleep was difficult. Shower was missing the shampoo dispenser. Water pressure wasn't the greatest. Bathroom sink had a broken drain plug. Only given 2 towels for 3 people. ..."
Reviewed on Jun 29, 2026

Forest Park Hotel by MDR
"Safe area, great location if doing things Forest Park area. Close to zoo & museums Rooms were clean & better than first impressions of outside. They r remodeling & updating. Staff was nice if we needed anything, helpful."
Reviewed on Jun 28, 2026
Midtown Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Midtown hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch
"It was convenient and located right at the St Louis Arch which we visited. It didn't have a lot of food places. We had to walk far to get to our room. We had to pay extra for valet parking because the self-parking garage was full. But it was a great old hotel for the price we paid."
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