Find a Hotel in Midtown
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch
Room was spotless. Only problem was the shower pin would not stay up so we had to take baths.
Reviewed on Feb 11, 2026

Pear Tree Inn St. Louis Airport
Clean room. Great staff.
Reviewed on Feb 12, 2026

Element St. Louis Midtown
Every single staff member that we spoke to was extremely nice and polite. Every part of the hotel was always clean, someone was mopping/cleaning the bathrooms in the lobby almost every time we were leaving or coming back in. The valet guys were great. They were polite, every time we left that told ...
Reviewed on Feb 16, 2026

21C Museum Hotel St Louis
Everything was superlative. Staff, hotel, room, pool.
Reviewed on Feb 11, 2026

Clayton Plaza Hotel & Extended Stay
Considering the price I wasn’t expecting such a nice place, from the entrance, to the easy parking, to the amazing breakfast… everything was so great and I would 1000% consider this place for my future stays in St. Louis! The staff was also very helpful and friendly!
Reviewed on Feb 12, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Zero complaints! Enjoyed our stay and will stay again!
Reviewed on Feb 15, 2026

Hyatt Regency St. Louis at The Arch
The first room we got was not the cleanliest and was really rundown. So we called down to the front desk and got a second room, which was much better and you could tell was remodeled in the bathroom. Smelled clean, looked clean unlike first room.
Reviewed on Feb 11, 2026

Residence Inn by Marriott St Louis Downtown
All good
Reviewed on Jan 20, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Coffee!! And the breakfast. Both were fantastic! Room was clean and nice except for the heating. Didn’t get much sleep due to a very noisy heating unit. Friendly people at check in and out.
Reviewed on Feb 8, 2026
Midtown Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Midtown hotel reviews by fellow wanderers

Element St. Louis Midtown
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