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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$153 nightly
The price is $179 total per night from Jun 28 to Jun 29
$179 total
Jun 28 - Jun 29
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
"Excellent hotel. Very convenient."

Reviewed on Jun 22, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $108 total per night from Jun 29 to Jun 30
$108 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
"Quick night trip for Father’s Day. Room was great and they had a lot of good food options."

Reviewed on Jun 22, 2026

Opens in a new windowRiver City Casino & Hotel
Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jul 12 to Jul 13
$158 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and valet parking. Relax with a ...
"This property is a great place with 1 exception: there was no hand soap for the bathroom. I requested some from the front desk and dish soap was sent up. I explained that I needed hand soap and was told they did not have any. I asked the ladies cleaning the rooms in the morning and received the same ..."

Reviewed on Jun 21, 2026

Opens in a new windowElement by Marriott St. Louis Midtown
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $206 total per night from Jul 19 to Jul 20
$206 total
Jul 19 - Jul 20
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"The room was clean and comfortable and the hotel had a cool rooftop bar and great decor."

Reviewed on Jun 23, 2026

Opens in a new windowMoonrise Hotel
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $119 total per night from Jul 12 to Jul 13
$119 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Everything"

Reviewed on Jun 22, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $169 total per night from Jun 28 to Jun 29
$169 total
Jun 28 - Jun 29
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"My favorite"

Reviewed on Jun 22, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $136 total per night from Jun 25 to Jun 26
$136 total
Jun 25 - Jun 26
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
"Restaurants not open late enough"

Reviewed on Jun 22, 2026

Opens in a new windowHollywood Casino & Hotel St. Louis
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $140 total per night from Jul 12 to Jul 13
$140 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...
"Fire alarm went off two days at 4am. Very inconvenient"

Reviewed on Jun 21, 2026

Opens in a new windowResidence Inn by Marriott St Louis Downtown
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $104 total per night from Jul 5 to Jul 6
$104 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the 24-hour business center, ...
"Great place to stay! Well recommended"

Reviewed on Jun 21, 2026

Opens in a new windowForest Park Hotel by MDR
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Midtown Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Midtown hotel reviews by fellow wanderers

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