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Oct 30 - Nov 1
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$144 nightly
The price is $168 total per night from Nov 1 to Nov 2
$168 total
Nov 1 - Nov 2
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
"Love the evening manager’s reception and the breakfast. Drury always exceeds expectations! Great location close to the Arch. Great stay!"

Reviewed on Oct 25, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $106 total per night from Oct 30 to Oct 31
$106 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Clean room Breakfast could have been better. Clean facility. Parking ok, not so good at night!! Dangerous to park so far in the back, after hours. Overall satisfy"

Reviewed on Oct 25, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $134 total per night from Nov 1 to Nov 2
$134 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Loved the location, amenities and large room with comfortable bed. We were able to walk to Enterprise Center. Particularly enjoyed the happy hour and breakfast. Did not appreciate the noise from the garbage collectors handling the huge dumpsters around 4am. For an upscale quality hotel you should ..."

Reviewed on Oct 23, 2026

Opens in a new windowDrury Plaza Hotel St. Louis Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $109 total per night from Nov 1 to Nov 2
$109 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"The staff go out of their way to be helpful and accommodating. The room was spacious, very clean and comfortable. Convenient parking, great breakfast! A great location in a safe neighborhood, within walking distance of several very good restaurants and a short trip to all the major attractions. I ..."

Reviewed on Oct 25, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $148 total per night from Nov 25 to Nov 26
$148 total
Nov 25 - Nov 26
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"I stayed there over the weekend and they were busy. They had several conferences there. The staff was all very well mannered and helpful to all the guest and shout out to valet team. That is worth every penny versus trying to find a place to park. I highly recommend and I will be back the next time ..."

Reviewed on Oct 25, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $83 total per night from Nov 24 to Nov 25
$83 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the 24-hour business center, ...
"The staff was accommodating as much as possible. The rooms were decent for the price during the week but when the weekend came it doubled in price. The vending machines didn’t work properly. Overall it’s a place to stay and food is nearby in walking distance."

Reviewed on Oct 25, 2026

Opens in a new windowForest Park Hotel by MDR
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $126 total per night from Nov 1 to Nov 2
$126 total
Nov 1 - Nov 2
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Opens in a new windowHollywood Casino & Hotel St. Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $122 total per night from Nov 22 to Nov 23
$122 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from Nov 22 to Nov 23
$122 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowPear Tree Inn St. Louis Near Union Station
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Midtown Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Midtown hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"I stayed there over the weekend and they were busy. They had several conferences there. The staff was all very well mannered and helpful to all the guest and shout out to valet team. That is worth every penny versus trying to find a place to park. I highly recommend and I will be back the next time I stay in St. Louis."
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch

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