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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $179 total per night from Jun 9 to Jun 10
$179 total
Jun 9 - Jun 10
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
"Check in was easy and very informative. Our was clean, Kick back time was great and breakfast was a full buffet."

Reviewed on Jun 4, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Jun 14 to Jun 15
$106 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Room was clean but very small"

Reviewed on Jun 3, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jun 14 to Jun 15
$158 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and valet parking. Relax with a ...
"The staff was incredibly nice and helpful. the room was clean and well organized. the mattress was a bit older and had sunken spot on one side so it likely needs to be replaced, but other than that I will stay there business trip to STL."

Reviewed on Jun 1, 2026

Opens in a new windowElement by Marriott St. Louis Midtown
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Jun 7 to Jun 8
$116 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean room and friendly staff."

Reviewed on Jun 5, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jun 9 to Jun 10
$143 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"everything about the service, amenities, location was perfect. the only complaint is that it’s outdated and can use quite a bit of upgrading."

Reviewed on Jun 5, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

3.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jun 11 to Jun 12
$143 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"It was an above average stay, the hotel was maintained. The pool was cold, great for summer. Breakfast was excellent and the staff for breakfast also great! No loyalty points were allowed as we had booked through an alternate booking site. That was disappointing. Overall we would stay again."

Reviewed on Jun 3, 2026

Opens in a new windowHampton Inn St. Louis-Downtown (At the Gateway Arch)
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Jun 12 to Jun 13
$162 total
Jun 12 - Jun 13
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"The property was very clean. The staff was helpful. I liked after we watched the baseball game, walking back to the hotel and sitting at the bar for a drink. That was very nice. A good night Sleep we’re very pleased."

Reviewed on Jun 5, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $140 total per night from Jun 28 to Jun 29
$140 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...
"We like staying there when we come down to see the Cardinals play ball. It's still close to everything. All went well again."

Reviewed on May 31, 2026

Opens in a new windowResidence Inn by Marriott St Louis Downtown
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $115 total per night from Jun 7 to Jun 8
$115 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"The breakfast was good. We had to constantly ask for towels"

Reviewed on Jun 5, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Midtown Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Midtown hotel reviews by fellow wanderers

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