Find a Hotel in Midtown
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Top hotels in Midtown

Drury Plaza Hotel St. Louis at the Arch
"Staff was friendly and accommodating. The room was a bit dated and tight."
Reviewed on Jun 7, 2026

Pear Tree Inn St. Louis Airport
"The staff were very helpful and congenial. The free shuttle to the airport was helpful. The coffee offered in the lobby (bespoke brand) was fantastic! I’ll stay here again."
Reviewed on Jun 7, 2026

Element by Marriott St. Louis Midtown
"During breakfast the woman cooking the breakfast was rude and seemed bothered when asked about the breakfast options."
Reviewed on Jun 6, 2026

Clayton Plaza Hotel & Extended Stay
"Good location, comfortable bed, and quiet"
Reviewed on Jun 7, 2026

Pear Tree Inn St. Louis Near Union Station
"Staff was great- very friendly and helpful. Location was very good as well, near to Union station with restaurants and activities. Hotel rooms and bathrooms need maintenance and work, paint falling off, pipes leaking in front of elevators on the 4th floor, outdoor had some litter around- in need ..."
Reviewed on Jun 7, 2026

Hyatt Regency St. Louis at The Arch
"The stay was excellent but when you are ready to leave getting your car is stressful we had to wait half-hour in line to retrieve our vehicle other than the stay was excellent"
Reviewed on Jun 7, 2026

Hollywood Casino & Hotel St. Louis
"This hotel is gorgeous! Spacious room and bathroom!"
Reviewed on Jun 7, 2026

Residence Inn by Marriott St Louis Downtown
"We like staying there when we come down to see the Cardinals play ball. It's still close to everything. All went well again."
Reviewed on May 31, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"First room we were put in had broken AC. Front desk was nice and gave us a different room. The room was musty and seemed to be damp in general. Hotel needs a lot of updating but all staff was polite and helpful."
Reviewed on Jun 7, 2026
Midtown Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Midtown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Midtown to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Midtown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Midtown hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Near Union Station
"Staff was great- very friendly and helpful. Location was very good as well, near to Union station with restaurants and activities. Hotel rooms and bathrooms need maintenance and work, paint falling off, pipes leaking in front of elevators on the 4th floor, outdoor had some litter around- in need of TLC."
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