Book Hotels in Melrose, FL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Melrose hotels

3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

Melrose FL
This vacation home features a garden, laundry facilities, and barbecue grills.
It was perfect for us. It is not far from our daughter’s house. The lake is a little low right now, but we enjoyed the fire pit and we were able to make food for my granddaughter’s birthday party in the kitchen. The beds were comfortable and the front porch was a hit with the guys.

Reviewed on Apr 4, 2026

Get rates
Opens in a new window3 Bedroom House on Private Scenic Lake Mable
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

3 out of 5
4000 Southwest 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Apr 19 to Apr 20
$127 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Breakfast is amazing, the service and cleanliness is also great.

Reviewed on Apr 8, 2026

Opens in a new windowDrury Inn & Suites Gainesville
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street Gainesville FL
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $201 total per night from Apr 19 to Apr 20
$201 total
Apr 19 - Apr 20
Total with taxes and fees
A restaurant and a gym are featured at this hotel. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
quick stay but enjoyable. Would definitely stay here again.

Reviewed on Apr 9, 2026

Opens in a new windowHotel Eleo at the University of Florida
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

3 out of 5
4015 Sw 43rd St Gainesville FL
Fully refundable
$88 nightly
The price is $99 total per night from Apr 19 to Apr 20
$99 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
It was better than we even expected. Staff, specifically Denise who checked us in, were all friendly and helpful. Room was very clean and comfortable. Indoor pool was very clean. Unfortunately we had to leave early so we were only able to grab and go from their complementary breakfast, but what we ...

Reviewed on Apr 9, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Gainesville, FL
Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG

3.5 out of 5
5020 SW 30th Lane Gainesville FL
Fully refundable
$116 nightly
The price is $131 total per night from Apr 26 to Apr 27
$131 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The staff were very nice and welcoming. The rooms were very clean and comfortable. Will revisit..

Reviewed on Apr 8, 2026

Opens in a new windowHotel Indigo Gainesville-Celebration Pointe by IHG
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 out of 5
4110 SW 40th Boulevard Gainesville FL
Fully refundable
$90 nightly
The price is $101 total per night from May 6 to May 7
$101 total
May 6 - May 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
There was a strong mildew smell. The shower curtain smell like if they were not properly dried.

Reviewed on Apr 8, 2026

Opens in a new windowSleep Inn & Suites University/Shands
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

2.5 out of 5
3905 Sw 43Rd St Gainesville FL
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Apr 15 to Apr 16
$87 total
Apr 15 - Apr 16
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The breakfast menu was fresh.and the parking felt safe. What really surprised me was how quiet the rooms were.

Reviewed on Apr 5, 2026

Opens in a new windowHOM Hotel Gainesville, SureStay Collection by Best Western
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Apr 26 to Apr 27
$109 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and free WiFi. A terrace, a garden, and a ...
Clean rooms and facilities. Great staff

Reviewed on Apr 8, 2026

Opens in a new windowDoubleTree by Hilton Gainesville
Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

2.5 out of 5
3500 Southwest 42nd St Gainesville FL
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Apr 15 to Apr 16
$74 total
Apr 15 - Apr 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock ...
The room had not been cleaned. Fingernail clippings were scattered on the floor. The bathroom was in terrible condition. I just wanted to leave as soon as possible.

Reviewed on Apr 8, 2026

Opens in a new windowRed Roof Inn PLUS+ Gainesville
Don't see what you're looking for?
See all available properties in Melrose
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Melrose?
Take some of the struggles out of traveling with young ones by staying in a family-friendly Melrose hotel. From special amenities to extra-helpful services, these stays come with perks that'll make your visit run like a dream: Rustic Fishing Cabin on Lake Swan, Melrose will help make your vacation the best one yet. It comes with an assortment of nice little touches, such as pet-friendly facilities and extra bedding. Also consider staying at Please relax and enjoy our 2 bedroom 2 bath home on beautiful Lake Swan.. It offers a firepit, a fireplace and plenty of opportunities to hang out together.
Where can I find cheap hotels in Melrose?
At Travelocity you'll find really nice hotels in Melrose at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Melrose rather than in Melrose. We may find you even better rates, too.
How do I find the best Melrose hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Melrose then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Melrose?
The cheapest hotel in Melrose is $74. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Melrose?
There are 872 hotels in Melrose on Travelocity.
What are the best hotels in Melrose?
Melrose has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Melrose for you!
When is the best time to visit Melrose?
If you want the joy of a fun-filled trip in peak season, visit Melrose during August, September and December. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, June and July.
When is the cheapest time to stay in Melrose?
Based on historic data is usually the cheapest month to visit Melrose. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Melrose?
There are multiple hotels in Melrose that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Melrose. We have plenty of kid-friendly hotels in Melrose to choose from on Travelocity!
Why book a hotel in Melrose through Travelocity?
Because we have the top hotels in Melrose! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Melrose on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Melrose hotel reviews by fellow wanderers

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Great property and staff"
A verified traveler stayed at Hyatt Place Gainesville Downtown
Hyatt Place Gainesville Downtown

Explore More Ways to Travel with Travelocity