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Top hotels in Medical Center

Atheneum Suite Hotel

Atheneum Suite Hotel

4 out of 5
1000 Brush Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $203 total per night from Jun 29 to Jun 30
$203 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"I loved the aesthetic of this hotel."

Reviewed on Jun 13, 2026

Opens in a new windowAtheneum Suite Hotel
The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

4 out of 5
1509 Broadway St. Detroit MI
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $162 total per night from Jul 6 to Jul 7
$162 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a garden are also offered.
"Really enjoyed the friendly staff. The robes and personalized welcome card were great touches. The location is excellent walking to many good spots especially to see any of the sport events."

Reviewed on Jun 12, 2026

Opens in a new windowThe Siren Hotel, an Ash Hotel
MotorCity Casino Hotel

MotorCity Casino Hotel

4.5 out of 5
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $228 total per night from Jul 6 to Jul 7
$228 total
Jul 6 - Jul 7
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
"Convenient location, great fitness center, easy parking and helpful staff. I was traveling for business so never went into the Casino but it was very separate so didn't create noise or any issues as a single business traveler."

Reviewed on Jun 12, 2026

Opens in a new windowMotorCity Casino Hotel
Hollywood Casino at Greektown

Hollywood Casino at Greektown

4 out of 5
1200 Saint Antoine St Detroit MI
$192 nightly
The price is $223 total per night from Jun 29 to Jun 30
$223 total
Jun 29 - Jun 30
Total with taxes and fees
A casino, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 10 conference rooms, business ...
"Room was dirty. Gum on the bed sheets. And gum on night stand. No coffee in room. No waste basket in bathroom."

Reviewed on Jun 13, 2026

Opens in a new windowHollywood Casino at Greektown
La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport

3 out of 5
30847 Flynn Drive Romulus MI
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Jul 5 to Jul 6
$88 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage ...
"Nice"

Reviewed on Jun 12, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Detroit Metro Airport
Trumbull and Porter Hotel

Trumbull and Porter Hotel

3.5 out of 5
1331 Trumbull St Detroit MI
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Jul 6 to Jul 7
$132 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Room was clean with a comfortable bed. However, the bathtub didn’t have any anti-slip in it. It was very slippery and we both also fell because of this. Otherwise everything else was great. Great location. Breakfast at the restaurant was good but the coffee was lukewarm warm and service average."

Reviewed on Jun 13, 2026

Opens in a new windowTrumbull and Porter Hotel
MGM Grand Detroit

MGM Grand Detroit

4.5 out of 5
1777 3rd Street Detroit MI
$223 nightly
The price is $259 total per night from Jun 29 to Jun 30
$259 total
Jun 29 - Jun 30
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 7 restaurants. Traveling on business? Take advantage of the express check-in, express check-out, ...
"A great place to stay."

Reviewed on Jun 13, 2026

Opens in a new windowMGM Grand Detroit
The Westin Southfield Detroit

The Westin Southfield Detroit

4 out of 5
1500 Town Center Southfield MI
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $135 total per night from Jun 21 to Jun 22
$135 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
"Although the property was clean the decor was very dated and worn. It was below the standard of a 4 star hotel."

Reviewed on Jun 13, 2026

Opens in a new windowThe Westin Southfield Detroit
Hotel Houze Detroit Downtown

Hotel Houze Detroit Downtown

3 out of 5
305 Michigan Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $153 total per night from Jun 21 to Jun 22
$153 total
Jun 21 - Jun 22
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
"It was clean and staff was helpful. Well appointed room with comfortable king bed and full kitchen appliances. Really the only problem was our TV didn't work and no one ever fixed it after 2 asks. We were in the room so little, it wasn't a big deal, but had we been, it would have been. It was really ..."

Reviewed on Jun 13, 2026

Opens in a new windowHotel Houze Detroit Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Medical Center hotel reviews by fellow wanderers

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