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Top hotels in Medical Center
Atheneum Suite Hotel
1000 Brush Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $203 total per night from Jun 29 to Jun 30
$203 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"great inside restaurant and bar. centrally located a plus! will stay again!"
Reviewed on Jun 8, 2026
The Siren Hotel, an Ash Hotel
1509 Broadway St. Detroit MI
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $155 total per night from Jul 7 to Jul 8
$155 total
Jul 7 - Jul 8
Total with taxes and fees
This hotel features a restaurant and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a garden are also offered.
"No mini fridge or microwave, small room, no coffee/tea machine, shower took forever to get hot, no bath tub, no parking included"
Reviewed on Jun 8, 2026
MotorCity Casino Hotel
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $228 total per night from Jul 6 to Jul 7
$228 total
Jul 6 - Jul 7
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
"There was 2 of us that stayed in a double room. BUT. They were double mattresses on queen sized platforms. As a result, both my friend and I kicked the edges of the beds several times. We both tripped and fell over the edges and I got a large bruise. I brought it up to front desk when checking out ..."
Reviewed on Jun 8, 2026
Hollywood Casino at Greektown
1200 Saint Antoine St Detroit MI
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $223 total per night from Jul 6 to Jul 7
$223 total
Jul 6 - Jul 7
Total with taxes and fees
A casino, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 10 conference rooms, business ...
"There were enough little things that were not right or working, especially for a room that was over $500 on a Friday. Paid to upgrade to have a soaking tub, that did not work. Toilet paper hanger was broke. No coffee cups or creamer. No plastic cups or glass ware, for a room like this, expected glasses. ..."
Reviewed on Jun 8, 2026
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
30847 Flynn Drive Romulus MI
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Jul 5 to Jul 6
$88 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage ...
"Was not very clean at all"
Reviewed on Jun 8, 2026
Trumbull and Porter Hotel
1331 Trumbull St Detroit MI
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $138 total per night from Jun 21 to Jun 22
$138 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"I didn't like the room, floors, bedding and bathroom area. The sheets were ripped. The face bowl was backed up and there was no maintenance on the property to fix it."
Reviewed on Jun 8, 2026
The Westin Southfield Detroit
1500 Town Center Southfield MI
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $135 total per night from Jun 21 to Jun 22
$135 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
"Overall stay was nice but I didn’t like the fact that they didn’t want to take cash to pay for snacks and I didn’t like that don’t give you complimentary breakfast with your stay"
Reviewed on Jun 8, 2026
Hotel Houze Detroit Downtown
305 Michigan Avenue Detroit MI
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $171 total per night from Jun 28 to Jun 29
$171 total
Jun 28 - Jun 29
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
"We stayed here this past weekend. The room itself was big & spacious. The front desk attendant however was pretty rude when we arrived. We are from out of town so tried to call & see if we could check in early but just got left on hold. Upon arrival (we were about 30-45 minutes early) we asked if ..."
Reviewed on Jun 8, 2026
MGM Grand Detroit
1777 3rd Street Detroit MI
$210 nightly
The price is $244 total per night from Jun 28 to Jun 29
$244 total
Jun 28 - Jun 29
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 7 restaurants. Traveling on business? Take advantage of the express check-in, express check-out, ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Medical Center Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Medical Center hotel reviews by fellow wanderers
The Westin Southfield Detroit
3 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Overall stay was nice but I didn’t like the fact that they didn’t want to take cash to pay for snacks and I didn’t like that don’t give you complimentary breakfast with your stay"
A verified traveler stayed at The Westin Southfield Detroit
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