Book a hotel near Lewis and Clark Interpretive Center, St. Louis
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top hotels close to Lewis and Clark Interpretive Center

Days Inn by Wyndham Downtown St. Louis
2810 N 9th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
11.39 mi from Lewis and Clark Interpretive Center
$81 nightly
The price is $94 total per night
$94 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.74 mi from Lewis and Clark Interpretive Center
$128 nightly
The price is $150 total per night
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.

Embassy Suites by Hilton St. Louis Downtown
610 N 7th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.75 mi from Lewis and Clark Interpretive Center
$122 nightly
The price is $145 total per night
$145 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, and valet parking. Relax with a drink at the bar/lounge and enjoy the free cooked-to-order breakfast.

Casino Queen Hotel
200 Front Street East St. Louis IL
Free Cancellation
Reserve now, pay when you stay
12.8 mi from Lewis and Clark Interpretive Center
$99 nightly
The price is $115 total per night
$115 total
Apr 5 - Apr 6
Total with taxes and fees
A casino and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the indoor pool and perks like free self parking.

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.85 mi from Lewis and Clark Interpretive Center
$124 nightly
The price is $147 total per night
$147 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a communal living room, and luggage storage are also on offer.

Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.91 mi from Lewis and Clark Interpretive Center
$102 nightly
The price is $119 total per night
$119 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and valet parking. A snack bar/deli and a safe deposit box are also provided.

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.97 mi from Lewis and Clark Interpretive Center
$148 nightly
The price is $173 total per night
$173 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the gym and conveniences like a 24-hour front desk and concierge services.

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13 mi from Lewis and Clark Interpretive Center
$152 nightly
The price is $179 total per night
$179 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
13.1 mi from Lewis and Clark Interpretive Center
$162 nightly
The price is $189 total per night
$189 total
Apr 7 - Apr 8
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy a meal from the restaurant and free buffet breakfast each morning.

Live by Loews - St.Louis
799 Clark ave St. Louis MO
13.24 mi from Lewis and Clark Interpretive Center
$149 nightly
The price is $177 total per night
$177 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and concierge services and free newspapers are also offered.

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.26 mi from Lewis and Clark Interpretive Center
$113 nightly
The price is $132 total per night
$132 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.35 mi from Lewis and Clark Interpretive Center
$141 nightly
The price is $168 total per night
$168 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Don't see what you're looking for?
See all available properties in Lewis and Clark Interpretive Center
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lewis and Clark Interpretive Center hotels essential information
Accommodation | 2,052 hotels |
|---|---|
Lowest Price | $94 |
Highest Price | $189 |
Popular hotels | Drury Plaza Hotel St. Louis at the Arch, Pear Tree Inn St. Louis Near Union Station, 21C Museum Hotel St Louis , Hyatt Regency St. Louis at The Arch, Days Inn by Wyndham Downtown St. Louis, Drury Inn & Suites St. Louis Union Station, Hampton Inn St. Louis-Downtown (At the Gateway Arch), Live by Loews - St.Louis, Home2 Suites by Hilton St. Louis Downtown, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Embassy Suites by Hilton St. Louis Downtown, Casino Queen Hotel |
Recent Lewis and Clark Interpretive Center hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Best location breakfast was great , cleanness. Room size modeeate"
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
More ways to wander Lewis and Clark Interpretive Center
Explore More Ways to Travel with Travelocity
- Hotels near Historic Museum of Torture Devices
- Hotels near Robert Wadlow Statue
- Hotels near Splash City Family Waterpark
- Collinsville Hotels
- Woods Hotels
- 5 Star Hotels in Wood River
- B&B in Wood River
- Extended Stay Hotels in Wood River
- Wood River Hotels
- Hotels near Lewis and Clark Confluence Tower
- Hotels near Gateway Fun Park
- Hotels near Cahokia Mounds State Historic Site
- Glen Carbon Hotels
- 4 Star Hotels in Roxana
- Extended Stay Hotels in Roxana
- Roxana Hotels
- Motels in Roxana
- Hotels near Alton Square Mall
- Hotels near Gateway Conference Center
- Cabins in Granite City
- Extended Stay Hotels in Granite City
- Hotels with Hot Tubs in Granite City
- Hotels with an Indoor Pool in Granite City
- Pet Friendly Hotels in Granite City
- Granite City Hotels
- Motels in Granite City
- Vacation Homes in Granite City
- Hotels near Edwardsville Watershed Nature Center
- Madison Hotels
- Hotels near FanDuel Sportsbook and Horse Racing
- Hotels near Argosy Casino
- Hotels near World Wide Technology Raceway
- Cabins in Pontoon Beach
- Extended Stay Hotels in Pontoon Beach
- Beach Resorts & in Pontoon Beach
- Hotels with Hot Tubs in Pontoon Beach
- Pet Friendly Hotels in Pontoon Beach
- Spa Resorts & in Pontoon Beach
- Pontoon Beach Hotels
- Motels in Pontoon Beach
- Vacation Homes in Pontoon Beach
- Hotels near Fast Eddie's Bon Air
- Condos in East Alton
- Extended Stay Hotels in East Alton
- East Alton Hotels
- Motels in East Alton
- Vacation Homes in East Alton
- Extended Stay Hotels in Hartford
- Hartford Hotels
- Alton Hotels
- Maryville Hotels
- Hotels near The Gardens at SIUE
- Farmstay in Edwardsville
- Apartments in Edwardsville
- B&B in Edwardsville
- Cabins in Edwardsville
- Condos in Edwardsville
- Cottages in Edwardsville
- Extended Stay Hotels in Edwardsville
- Best Western Hotels in Edwardsville
- Cheap Hotels in Edwardsville
- Drury Inn & Suites Hotels in Edwardsville
- Kid Friendly Hotels in Edwardsville
- Hotels with Pools in Edwardsville
- Hotels with Hot Tubs in Edwardsville
- Hotels with an Indoor Pool in Edwardsville
- Pet Friendly Hotels in Edwardsville
- Hotel Wedding Venues Hotels in Edwardsville
- Winery Hotels in Edwardsville
- Edwardsville Hotels
- Motels in Edwardsville
- Vacation Homes in Edwardsville
- Fairmont City Hotels
- Bethalto Hotels
- Cottage Hills Hotels
- Car rental Wood River
- Car rental Roxana
- Car rental Granite City
- Van Car Rentals in Granite City
- Car rental Pontoon Beach
- Pickup Car Rentals in Pontoon Beach
- Car rental East Alton
- Car rental Alton
- Car rental Edwardsville
- Luxury Car Rentals in Edwardsville
- Minivan Car Rentals in Edwardsville
- Pickup Car Rentals in Edwardsville
- Van Car Rentals in Edwardsville





