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Top hotels in Grand Center

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$154 nightly
The price is $180 total per night from May 18 to May 19
$180 total
May 18 - May 19
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
The staff from check in to the staff at breakfast was amazing. Everyone was so friendly and helpful. The hotel is beautiful and very well kept. Very clean. Breakfast is amazing.

Reviewed on May 10, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from May 24 to May 25
$189 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Nice place.

Reviewed on May 10, 2026

Opens in a new windowLive by Loews - St.Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 31 to Jun 1
$173 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Loved the look of the building and where it was located but the one thing I didn't like was there was no stairs. Everyone had to use the elevator.

Reviewed on May 9, 2026

Opens in a new window21C Museum Hotel St Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $144 total per night from May 24 to May 25
$144 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Perfect. Highly recommend. My wife left her jewelry in the room after we checked out, the house cleaner found them and saved them for her. Definitely will stay again. Great location across the street from the Fox.

Reviewed on May 6, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from May 31 to Jun 1
$116 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
It wasn’t a bad stay it is right next to the jail which is a little sketchy. The room was clean! The AC was super loud when it would turn on and off.

Reviewed on May 10, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
I did not have breakfast

Reviewed on May 10, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
White House at Grand Central

White House at Grand Central

3.5 out of 5
3805 Lindell Blvd St. Louis MO
$105 nightly
The price is $117 total per night from May 17 to May 18
$117 total
May 17 - May 18
Total with taxes and fees
This apartment features a garden, express check-out, and laundry facilities. If you want to take your pet along, this pet-friendly property offers everything ...
Room smelled of cigarettes, had to leave and book another property, check in and location was awful and hard to find. Property is nothing like it is described in booking. Bed was comfortable for the one night I stayed

Reviewed on Apr 25, 2026

Opens in a new window White House at Grand Central
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
The hotel was clean and looked amazing. Apart from the first employee we talked to, he was great, the others were awful. Waited ages for a drink until another employee walked by. No “how was your stay” or “thanks for staying” or nothing when we checked out. Just a rude “printed receipt or email.” ...

Reviewed on May 8, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from May 17 to May 18
$103 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Had a great experience with this hotel for 3dys, the rooms were clean, the indoor pool was nice with the jaccuzzi and breakfast was good!

Reviewed on May 9, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Grand Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Grand Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Grand Center hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Room was outdated. "
A verified traveler stayed at Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Near Union Station

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