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Top hotels in Grand Center

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $189 total per night from May 9 to May 10
$189 total
May 9 - May 10
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Nice hotel, helpful staff, and excellent location.

Reviewed on May 3, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from May 7 to May 8
$189 total
May 7 - May 8
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Clean and comfortable and great location

Reviewed on May 3, 2026

Opens in a new windowLive by Loews - St.Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from May 10 to May 11
$106 total
May 10 - May 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
The hotel stood out for the staff and amenities. It was a six-minute shuttle from the airport. In addition to normal breakfast, they made some items + coffee available at 3 a.m. When our 6 a.m. flight was cancelled the front desk staff told us we could come back to the room to sleep and offered us ...

Reviewed on May 4, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 31 to Jun 1
$173 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
All the restaurants and bar were excellent.

Reviewed on May 4, 2026

Opens in a new window21C Museum Hotel St Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from May 10 to May 11
$154 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
The color thing is interesting, but I would have appreciated more attention to some basics. For example, when I went to turn the TV off, it turned out there were no batteries in the remote control. There were no instructions on the phone that explained how to reach the front desk. There were no USB ...

Reviewed on May 4, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$105 nightly
The price is $122 total per night from May 17 to May 18
$122 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The front desk staff should better explain which elevator to take to reach the guest room.

Reviewed on May 4, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Wonderful time

Reviewed on May 4, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
 White House at Grand Central

White House at Grand Central

3.5 out of 5
3805 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $131 total per night from May 10 to May 11
$131 total
May 10 - May 11
Total with taxes and fees
This apartment features a garden, express check-out, and laundry facilities. If you want to take your pet along, this pet-friendly property offers everything ...
Room smelled of cigarettes, had to leave and book another property, check in and location was awful and hard to find. Property is nothing like it is described in booking. Bed was comfortable for the one night I stayed

Reviewed on Apr 25, 2026

Opens in a new window White House at Grand Central
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from May 17 to May 18
$103 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Bring your pet! Pet friendly, great breakfast, great customer service!!!!

Reviewed on May 4, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Grand Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Grand Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Grand Center hotel reviews by fellow wanderers

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