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Top hotels in Grand Center

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Jan 6 to Jan 7
$168 total
Jan 6 - Jan 7
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
good food and cleanroom nice employees

Reviewed on Jan 1, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Jan 25 to Jan 26
$173 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to ...

Reviewed on Dec 22, 2025

Opens in a new window21C Museum Hotel St Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $134 total per night from Jan 5 to Jan 6
$134 total
Jan 5 - Jan 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Great property.

Reviewed on Dec 22, 2025

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Jan 30 to Jan 31
$110 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Everything was nice

Reviewed on Dec 31, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $114 total per night from Jan 14 to Jan 15
$114 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Staff was great and the hotel was in a good location.

Reviewed on Jan 1, 2026

Opens in a new windowHampton Inn St. Louis-Downtown (At the Gateway Arch)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$97 nightly
The price is $115 total per night from Jan 25 to Jan 26
$115 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great accommodations and I loved the pet friendly environment! Looking forward to trying more of the in-room dining options next time.

Reviewed on Dec 30, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
 White House at Grand Central

White House at Grand Central

4 out of 5
3805 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $145 total per night from Jan 20 to Jan 21
$145 total
Jan 20 - Jan 21
Total with taxes and fees
This apartment features a garden, express check-out, and laundry facilities. The front desk is staffed around-the-clock and barbecue grills are on offer.
The property was wonderful, perfect, beautiful. We loved it

Reviewed on Nov 25, 2025

Opens in a new window White House at Grand Central
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $152 total per night from Jan 2 to Jan 3
$152 total
Jan 2 - Jan 3
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
We didn’t eat breakfast. Room was clean and tidy. Not enough conditioner in the container to cleanse hair. Only complaint.

Reviewed on Dec 30, 2025

Opens in a new windowHyatt Regency St. Louis at The Arch
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $91 total per night from Jan 14 to Jan 15
$91 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
I like

Reviewed on Dec 26, 2025

Opens in a new windowHome2 Suites by Hilton St. Louis Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Grand Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Grand Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Grand Center hotel reviews by fellow wanderers

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