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Top hotels in Grand Center

Drury Inn & Suites St. Louis Union Station
"This was my first time staying in a Drury Inn and it will not be my last! The breakfast was awesome but the best part was the 5:30 kickback!!!! We didn't need to spend any money on food!! When you step out the front doors....there's Union Station!! We were very pleased."
Reviewed on May 23, 2026

Clayton Plaza Hotel & Extended Stay
"We had stayed here previously and really enjoyed the stay. The breakfast is fantastic. Best breakfast for a hotel that i have ever had for a hotel. Rooms were very nice and updated. I would highly recommend this hotel and I will stay here again."
Reviewed on May 23, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
"Came to town, for a show at the Fox. Couldn't ask for a better location to the Fox! Room was clean and the staff was very helpful. Will be staying here again!"
Reviewed on May 22, 2026

Pear Tree Inn St. Louis Near Union Station
"Nice hotel. Close to many things."
Reviewed on May 22, 2026

Hyatt Regency St. Louis at The Arch
"Short walk to Busch Stadium. Definitely recommend."
Reviewed on May 22, 2026

White House at Grand Central
"The only hiccup I had with check in was that the link to pay the deposit didn’t work properly. With the check in location being other than the location of the room. Fortunately I was able to handle check in over the phone."
Reviewed on May 18, 2026

Hollywood Casino & Hotel St. Louis
"It’s just okay, weekdays breakfast not good from one and only coffee shop, pastries taste like yesterday."
Reviewed on May 22, 2026

Renaissance St. Louis Airport Hotel
"Xxx Essex d z"
Reviewed on May 22, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"Paid for an upgraded suite only to be told at check in - the room had never been cleaned and we were downgraded to a small room with only 2 beds for 3 adults. At first, we were offered a room with one king bed, so at least grateful for the second option. We were still charged the upgraded price and ..."
Reviewed on May 21, 2026
Grand Center Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Grand Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Center to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Grand Center hotel reviews by fellow wanderers

Clayton Plaza Hotel & Extended Stay
"We had stayed here previously and really enjoyed the stay. The breakfast is fantastic. Best breakfast for a hotel that i have ever had for a hotel. Rooms were very nice and updated. I would highly recommend this hotel and I will stay here again."
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