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Top hotels in Grand Center

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $101 total per night from May 3 to May 4
$101 total
May 3 - May 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Great for a stay before an early flight. Shuttle was right on time and convenient. I wish they had a grab and go breakfast selection for early morning flights before their regular breakfast hours. Staff was friendly and courteous.

Reviewed on Apr 25, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $166 total per night from May 3 to May 4
$166 total
May 3 - May 4
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Hot tub was dirty

Reviewed on Apr 25, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from May 10 to May 11
$122 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Only reason picked was for the indoor pool and game room for kids but was closed. Would've been nice to no before booking it they have a no refund policy

Reviewed on Apr 24, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 24 to May 25
$173 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The staff was great and willing to help. They even ran my uber eats up to my room and new key cards. This hotel will be my go-to when back in St. Louis.

Reviewed on Apr 22, 2026

Opens in a new window21C Museum Hotel St Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from May 9 to May 10
$154 total
May 9 - May 10
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Great stay

Reviewed on Apr 24, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Great food, great staff!

Reviewed on Apr 24, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
 White House at Grand Central

White House at Grand Central

3.5 out of 5
3805 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from May 10 to May 11
$132 total
May 10 - May 11
Total with taxes and fees
This apartment features a garden, express check-out, and laundry facilities. If you want to take your pet along, this pet-friendly property offers everything ...
Room smelled of cigarettes, had to leave and book another property, check in and location was awful and hard to find. Property is nothing like it is described in booking. Bed was comfortable for the one night I stayed

Reviewed on Apr 25, 2026

Opens in a new window White House at Grand Central
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Apr 26 to Apr 27
$143 total
Apr 26 - Apr 27
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
We were looking for a nice easy and safe stay in the St Louis area. This place was it. Staff is great food choices excellent and at no point did I feel like I was going to be stabbed. My best trip to St Louis yet!

Reviewed on Apr 23, 2026

Opens in a new windowHollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from May 17 to May 18
$103 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Staff at check-in was very friendly and helpful.

Reviewed on Apr 25, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Grand Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Grand Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Grand Center hotel reviews by fellow wanderers

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