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Top hotels in East Seneca

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $173 total per night from Jun 7 to Jun 8
$173 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport ...
"Night staff and day shuttle driver excelent Good breakfast"

Reviewed on May 31, 2026

Opens in a new windowWyndham Garden Buffalo Downtown
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $220 total per night from Jun 7 to Jun 8
$220 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Water temperature in tub and sink was pretty hot with warm water coming out of both faucets st sink!"

Reviewed on Jun 1, 2026

Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $145 total per night from Jun 2 to Jun 3
$145 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"open parking and staffs were amazing and quick with the services we needed"

Reviewed on May 30, 2026

Opens in a new windowBuffalo Airport Hotel
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

3 out of 5
6619 Transit Rd Buffalo NY
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $134 total per night from Jun 7 to Jun 8
$134 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
"Clean room. Employees very nice. Hot small breakfast in the morning. Overall good stay."

Reviewed on May 31, 2026

Opens in a new windowLa Quinta Inn by Wyndham Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
$103 nightly
The price is $117 total per night from Jun 29 to Jun 30
$117 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
"Convenient to Ontario Niagara Falls & other tasty local restaurants, house keeping was great, the sofa sleeper was extremely uncomfortable (mattress was dated and thin)."

Reviewed on Jun 1, 2026

Opens in a new windowSleep Inn & Suites Buffalo Airport
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Jun 9 to Jun 10
$97 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"We chose the hotel for its proximity to the thruway & the jacuzzi tub. It was not working & we had to call the desk. They were going to see if they could move us to a different room but discovered the maintenance man was there. He came relatively quickly but had to leave for a new nob for the control. ..."

Reviewed on May 31, 2026

Opens in a new windowGarden Place Hotel
CenterWay Hotel Buffalo North Near University

CenterWay Hotel Buffalo North Near University

2 out of 5
225 Crestmount Avenue Tonawanda NY
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from Jun 21 to Jun 22
$73 total
Jun 21 - Jun 22
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. A snack bar/deli and luggage storage are ...
"The first room they gave me was dirty, the second one had someone sleeping in it, and the hallways were dirty."

Reviewed on May 31, 2026

Opens in a new windowCenterWay Hotel Buffalo North Near University
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $132 total per night from Jun 2 to Jun 3
$132 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
"Check was smooth, but the television in the room did not work not did the air conditioning. We were given a new room, where the air conditioning also did not work. We also needed and extra towel and they gave us a floor mat, which i had to go and get myself"

Reviewed on Jun 1, 2026

Opens in a new windowM Hotel Buffalo
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Studio 6 Corporate Extended Stay Buffalo Amherst NY

2.5 out of 5
125 Inn Keepers Ln Buffalo NY
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $86 total per night from Jun 2 to Jun 3
$86 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A safe deposit box and laundry facilities are also provided.
"I never got my room. There wasn’t anyone on site to check me in. The lobby floor needed to be vacuumed. And there were people actually living there huddling in a large circle in front of the building chain smoking cigarettes."

Reviewed on May 29, 2026

Opens in a new windowStudio 6 Corporate Extended Stay Buffalo Amherst NY
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Seneca hotel reviews by fellow wanderers

Holiday Inn Express Cheektowaga North East by IHG

Holiday Inn Express Cheektowaga North East by IHG

2 out of 5
Posted less than an hour ago
Travelocity Verified Review
"The bathroom was not very clean. The ceiling fan was full of dust. The toilet ran constantly and wouldn't flush all the time. Drywall was pealing by the shower. There was hair all over the shower wall. The headboard was full of greasy spots. Like oily heads were against the headboard. Beds were comfortable but the sheets were itchy. Breakfast was great!"
A verified traveler stayed at Holiday Inn Express Cheektowaga North East by IHG
Holiday Inn Express Cheektowaga North East by IHG

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