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Top hotels in East Seneca

Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst

3 out of 5
5020 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $153 total per night from Apr 12 to Apr 13
$153 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Intuitively comfortable and accommodating. I would expect to pay much more for such a great stay.

Reviewed on Apr 8, 2026

Opens in a new windowHyatt Place Buffalo/Amherst
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $154 total per night from Apr 26 to Apr 27
$154 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport ...
Highly recommend this hotel. From the brhining to our departure the staff was amazing .

Reviewed on Apr 11, 2026

Opens in a new windowWyndham Garden Buffalo Downtown
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3 out of 5
145 Innkeepers Lane Buffalo NY
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Apr 26 to Apr 27
$103 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
clean room, breakfast was great, staff was friendly

Reviewed on Apr 7, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Buffalo Amherst
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 out of 5
131 Buell Ave Buffalo NY
Fully refundable
$114 nightly
The price is $130 total per night from Apr 19 to Apr 20
$130 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Very good

Reviewed on Apr 10, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Buffalo-Airport by IHG
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $88 total per night from Apr 30 to May 1
$88 total
Apr 30 - May 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Probably the most comfortable hotel bed I've ever slept on. Room was clean and had all I needed to sleep and shower as I was there only about 10 hours. However, the hallways desperately needed to be vacuumed and I could hear people just hanging out in the hall talking at 10pm and someone stomping ...

Reviewed on Apr 9, 2026

Opens in a new windowBuffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
$76 nightly
The price is $87 total per night from Apr 19 to Apr 20
$87 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Nice breakfast, property is a bit older but well cared for, room was clean. No issues. Would book again!

Reviewed on Apr 11, 2026

Opens in a new windowSleep Inn & Suites Buffalo Airport
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $86 total per night from Apr 12 to Apr 13
$86 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a 24-hour gym and a sauna. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
We didn't have breakfast. Thought we help ourselves but had to order? Its like restaurant. Thats why we went out for breakfast

Reviewed on Apr 10, 2026

Opens in a new windowGarden Place Hotel
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
$125 nightly
The price is $142 total per night from Apr 12 to Apr 13
$142 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
Badrooms not really clean and oxided in some parts, not really in good conditions, window of the room present a leak that coming from the exterior. Bedrooms really unconfortable. Need a bigger remodelling. Staff really good.

Reviewed on Apr 10, 2026

Opens in a new windowM Hotel Buffalo
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
$161 nightly
The price is $188 total per night from May 3 to May 4
$188 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Seneca hotel reviews by fellow wanderers

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