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Top hotels in East Seneca

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from May 28 to May 29
$163 total
May 28 - May 29
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport ...
"This hotel was clean and comfy"

Reviewed on May 26, 2026

Opens in a new windowWyndham Garden Buffalo Downtown
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $186 total per night from May 28 to May 29
$186 total
May 28 - May 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Personal kind of rude"

Reviewed on May 26, 2026

Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $145 total per night from May 31 to Jun 1
$145 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Very convenient location to the airport and the restaurant is attached easy to get to and from."

Reviewed on May 26, 2026

Opens in a new windowBuffalo Airport Hotel
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

3 out of 5
6619 Transit Rd Buffalo NY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $128 total per night from May 31 to Jun 1
$128 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
"Was able to leave car there to take shuttle to airport"

Reviewed on May 26, 2026

Opens in a new windowLa Quinta Inn by Wyndham Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
$112 nightly
The price is $128 total per night from Jun 7 to Jun 8
$128 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
"Great! Highly recommend anyone staying here!"

Reviewed on May 26, 2026

Opens in a new windowSleep Inn & Suites Buffalo Airport
CenterWay Hotel Buffalo North Near University

CenterWay Hotel Buffalo North Near University

2 out of 5
225 Crestmount Avenue Tonawanda NY
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from Jun 16 to Jun 17
$73 total
Jun 16 - Jun 17
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. A snack bar/deli and luggage storage are ...
"The staff was very friendly and helpful. We changed our room to the room with two beds, but the heating/cooling system was not working, which we were asked first if it was okay since they only have two rooms with the two twin beds. We were fine with it. He would have adjusted the price for inconvience, ..."

Reviewed on May 26, 2026

Opens in a new windowCenterWay Hotel Buffalo North Near University
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Jun 10 to Jun 11
$97 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"The room was very clean & but at a very affordable price. The breakfast was very basic by at least they had some bagels & coffee."

Reviewed on May 26, 2026

Opens in a new windowGarden Place Hotel
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $147 total per night from May 31 to Jun 1
$147 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
"Good"

Reviewed on May 26, 2026

Opens in a new windowM Hotel Buffalo
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Studio 6 Corporate Extended Stay Buffalo Amherst NY

2.5 out of 5
125 Inn Keepers Ln Buffalo NY
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from May 31 to Jun 1
$73 total
May 31 - Jun 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A safe deposit box and laundry facilities are also provided.
"Staff was rude when I called about check in. When I got there no one was there"

Reviewed on May 26, 2026

Opens in a new windowStudio 6 Corporate Extended Stay Buffalo Amherst NY
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Seneca hotel reviews by fellow wanderers

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Chrissy’s furdydufifufivivochtjgk. Fuudjfigify"
A verified traveler stayed at Hampton Inn Buffalo - Amherst, NY
Hampton Inn Buffalo - Amherst, NY

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