Explore top 2025 5 Star Hotels in South Carolina Lowcountry

Name: Montage Palmetto Bluff Residences
Price range: $1,716 total

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Top South Carolina Lowcountry 5 Star hotels

Montage Palmetto Bluff

477 Mount Pelia Road, Bluffton, SC

$510 nightly

$561 total

Dec 1 - Dec 2

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and a marina. There's fun for all ages with a children's club and a children's pool, and babysitting ...

9.4/10 Exceptional! (248 reviews)

The Montage is truly the most breathtaking destination in the Lowcountry. A fall stay here is especially magical—the setting feels whimsical, almost like being transported into a dream. From the stunning atmosphere to the exceptional food and drink, every detail is top-notch. Highly recommend.

Reviewed on Sep 29, 2025

Anchorage 1770

1103 Bay Street, Beaufort, SC

Fully refundableReserve now, pay when you stay

$274 nightly

$301 total

Dec 3 - Dec 4

Total with taxes and fees

This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...

9.2/10 Wonderful! (217 reviews)

Great property at a wonderful location.

Reviewed on Oct 28, 2025

Montage Palmetto Bluff Residences

1 Village Park Square, Bluffton, SC

$1,560 nightly

$1,716 total

Nov 16 - Nov 17

Total with taxes and fees

This luxury vacation home features a golf course, a full-service spa, and a marina. Bring the family and enjoy the children's club, children's pool, and playground. ...

This was our second visit to Montage Palmetto Bluff and once again it did not disappoint. The hospitality we find here is second to none. Everywhere we went we were greeted with smiling faces. We’d like to give a special shout out to Carmela at the concierge desk who was so incredibly wonderful with ...

Reviewed on Jan 14, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Carolina Lowcountry Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in South Carolina Lowcountry to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. South Carolina Lowcountry 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in South Carolina Lowcountry before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.