Explore the best 2025 4 Star Hotels Hotels in West Main Historic District
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Top West Main Historic District 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$133 nightly
The price is $156 total per night
$156 total
Jul 1 - Jul 2
Total includes taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Spa
Pet friendly

Omni Louisville Hotel
400 S. 2nd Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$199 nightly
The price is $234 total per night
$234 total
Jun 14 - Jun 15
Total includes taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Spa

Hotel Genevieve
730 E Market St, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$140 nightly
The price is $165 total per night
$165 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
Pet friendly
Free WiFi

Derby City Gaming & Hotel - A Churchill Downs Property
4520 Poplar Level Rd, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$104 nightly
The price is $123 total per night
$123 total
Jun 3 - Jun 4
Total includes taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop, luggage storage, and concierge services are also on offer.
Parking included
Free WiFi

The Brown Hotel
335 W Broadway, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $211 total per night
$211 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Valet parking, a coffee shop, and dry cleaning are also offered.
Free airport shuttle
Free WiFi

Embassy Suites Louisville Downtown
501 South Fourth Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$135 nightly
The price is $159 total per night
$159 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet parking, a 24-hour business center, and a grocery/convenience store are also offered.
Pool
Breakfast included

Louisville Marriott Downtown
280 West Jefferson Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$171 nightly
The price is $201 total per night
$201 total
Jun 13 - Jun 14
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.
Pool
Free WiFi

Marriott Louisville East
1903 Embassy Square Blvd, Louisville, KY
$103 nightly
The price is $123 total per night
$123 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a 24-hour gym on site, and a 24-hour front desk and a coffee shop are also provided.
Pool
Free WiFi

Hyatt Regency Louisville
320 West Jefferson Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$133 nightly
The price is $156 total per night
$156 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a gym on site, and concierge services and wedding services are also offered.
Pool
Free WiFi

The Grady
601 W Main St, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$224 nightly
The price is $264 total per night
$264 total
Jun 7 - Jun 8
Total includes taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.
Pet friendly
Free WiFi

21c Museum Hotel Louisville
700 W Main Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$174 nightly
The price is $205 total per night
$205 total
Jun 30 - Jul 1
Total includes taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the gym, bar/lounge, and laundry facilities.
Spa
Pet friendly

Hotel Distil, Autograph Collection
101 West Main Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$175 nightly
The price is $206 total per night
$206 total
Jul 2 - Jul 3
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and express check-out are also provided.
Pet friendly
Free WiFi
Don't see what you're looking for?
See all available properties in West Main Historic District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
West Main Historic District hotels essential information
Accommodation | 1,969 hotels |
---|---|
Lowest Price | $123 |
Highest Price | $264 |
Popular hotels | Galt House Hotel Trademark Collection by Wyndham, Omni Louisville Hotel, Hotel Genevieve, Derby City Gaming & Hotel - A Churchill Downs Property , The Brown Hotel, Embassy Suites Louisville Downtown, Louisville Marriott Downtown, Marriott Louisville East, Hyatt Regency Louisville, The Grady, 21c Museum Hotel Louisville, Hotel Distil, Autograph Collection |
Recent West Main Historic District hotel reviews by fellow wanderers

21c Museum Hotel Louisville
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"We were able to check in early. Room is clean and breakfast is great. "
A verified traveler stayed at 21c Museum Hotel Louisville
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