Explore top 2026 4 Star Hotels in Clayton
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Top Clayton 4 Star hotels
Omni Severin Hotel
40 West Jackson Place Indianapolis IN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Aug 9 to Aug 10
$179 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.4/10 Exceptional! (1,204 reviews)
"Clean room, nice friendly staff."
Reviewed on Jul 31, 2026
JW Marriott Indianapolis
10 S West Street Indianapolis IN
$232 nightly
The price is $272 total per night from Aug 4 to Aug 5
$272 total
Aug 4 - Aug 5
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Hyatt Regency Indianapolis
One South Capitol Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $180 total per night from Aug 10 to Aug 11
$180 total
Aug 10 - Aug 11
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (1,000 reviews)
"The room was very clean and the staff very kind and helpful"
Reviewed on Jul 28, 2026
Marriott Indianapolis Downtown
350 W Maryland St Indianapolis IN
Fully refundableReserve now, pay when you stay
$185 nightly
The price is $217 total per night from Aug 2 to Aug 3
$217 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features 2 bars/lounges and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A restaurant, ...
9.2/10 Wonderful! (1,090 reviews)
"Thanks again for everything ❤️"
Reviewed on Jul 30, 2026
Bottleworks Hotel
850 Massachusetts Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $240 total per night from Aug 2 to Aug 3
$240 total
Aug 2 - Aug 3
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the steam room and perks like free WiFi. A bar/lounge, a 24-hour ...
Sheraton Indianapolis City Centre Hotel
31 W Ohio St Indianapolis IN
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $168 total per night from Aug 4 to Aug 5
$168 total
Aug 4 - Aug 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.4/10 Very Good! (1,000 reviews)
"The staff was friendly and the bed was super comfortable. Unfortunately even though our check in was scheduled for 3pm we weren't able to actually get checked into our room til after 5 due to the unavailability of there suites due to 100% occupancy the night before which put us behind on our reservations ..."
Reviewed on Jul 29, 2026
The Westin Indianapolis
241 W Washington Street Indianapolis IN
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $209 total per night from Aug 9 to Aug 10
$209 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
InterContinental Indianapolis by IHG
17 West Market Street Indianapolis IN
Fully refundable
$209 nightly
The price is $246 total per night from Aug 24 to Aug 25
$246 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also ...
Hilton Indianapolis Hotel & Suites
120 W Market St Indianapolis IN
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $173 total per night from Aug 9 to Aug 10
$173 total
Aug 9 - Aug 10
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.8/10 Excellent! (1,000 reviews)
"The soap dispenser in the shower was empty and the shampoo was not even there. The dispenser was not even on the wall. Couldn’t use the coffee pot as some of the components were missing! Seems like it was very quickly gone through. One of the water bottles that they bragged about having in the room ..."
Reviewed on Jul 28, 2026
The Alexander, Autograph Collection
333 S Delaware St Indianapolis IN
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $281 total per night from Aug 2 to Aug 3
$281 total
Aug 2 - Aug 3
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, conference ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Clayton
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Clayton 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Clayton will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Clayton, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Clayton hotel reviews by fellow wanderers
Home2 Suites by Hilton Indianapolis Downtown
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Nice hotel right downtown. Close enough to walk downtown and mass ave. Breakfast was good, room was clean, pool had lots of towels. Valet was not good though. Get message the car is ready only to wait 20 minutes after coming downstairs. Better off parking across the street."
A verified traveler stayed at Home2 Suites by Hilton Indianapolis Downtown
