Explore top 2025 4 Star Hotels in Clarksville

Name: Hotel Distil, Autograph Collection
Price range: $206 total
Rating: 9.4

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Top Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$133 nightly

$157 total

Nov 25 - Nov 26

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,735 reviews)

Very clean room. However the landline hotel room phones did not work so you couldn’t call the front desk. Also there was no microwave. Overall very nice hotel and staff.

Reviewed on Nov 9, 2025

Omni Louisville Hotel

400 S. 2nd Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$199 nightly

$234 total

Nov 24 - Nov 25

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.2/10 Wonderful! (1,668 reviews)

Gorgeous room and great service

Reviewed on Nov 8, 2025

Derby City Gaming & Hotel - A Churchill Downs Property

4520 Poplar Level Rd, Louisville, KY

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Nov 16 - Nov 17

Total with taxes and fees

This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...

9.4/10 Exceptional! (1,594 reviews)

Spotless

Reviewed on Nov 9, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Nov 21 - Nov 22

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...

8.8/10 Excellent! (1,054 reviews)

Loved everything about it

Reviewed on Nov 8, 2025

The Brown Hotel

335 W Broadway, Louisville, KY

Fully refundableReserve now, pay when you stay

$168 nightly

$198 total

Nov 23 - Nov 24

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,104 reviews)

A real hotel. Classic. Great staff. Food excellent. Room spacious and comfortable.

Reviewed on Nov 6, 2025

Hotel Genevieve part of JdV by Hyatt

730 E Market St, Louisville, KY

Fully refundableReserve now, pay when you stay

$135 nightly

$159 total

Nov 16 - Nov 17

Total with taxes and fees

This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.

9.2/10 Wonderful! (1,000 reviews)

Loved the room

Reviewed on Nov 6, 2025

Hyatt Regency Louisville

320 West Jefferson Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$129 nightly

$152 total

Nov 20 - Nov 21

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.6/10 Excellent! (1,000 reviews)

Hotel itself was great, our room was clean, air/heat worked great. We had no issues whatsoever. We were there for an event so the traffic for the elevator was pretty heavy. Would definitely stay again. We did not order room service and the restaurants attached to the hotel unfortunately weren’t very ...

Reviewed on Oct 31, 2025

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$183 nightly

$216 total

Nov 20 - Nov 21

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,002 reviews)

Bed was comfortable, room was large, bathroom was OK. Staff was kind. Wish the breakfast opened earlier on Sunday.

Reviewed on Nov 3, 2025

The Grady

601 W Main St, Louisville, KY

Fully refundableReserve now, pay when you stay

$188 nightly

$221 total

Nov 23 - Nov 24

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

9.4/10 Exceptional! (1,003 reviews)

It was a wonderful stay. The hotel is beautiful and new. Very clean. Our server Mark in the restaurant was exceptional! Kevin that checked us in was efficient and so informative. The breakfast at Wild Swann.... the biscuits oh the biscuits!!!!

Reviewed on Nov 9, 2025

Hotel Distil, Autograph Collection

101 West Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$175 nightly

$206 total

Nov 27 - Nov 28

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.4/10 Exceptional! (422 reviews)

Very modern and comfortable hotel. Great bar and attached restaurant. Location excellent.

Reviewed on Nov 8, 2025

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4 Star Hotels Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.