Book Hotels in Santa Fe, FL
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Top Santa Fe hotels

Hotel Eleo at the University of Florida
1514 Southwest 14th Street Gainesville FL
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $161 total per night from Nov 16 to Nov 17
$161 total
Nov 16 - Nov 17
Total with taxes and fees
A restaurant and a gym are featured at this hotel. WiFi in public areas is free. Valet parking and luggage storage are also offered on site.
Clean room, nice staff. AC in room works in a strange way. Interrupts nights sleep.
Reviewed on Nov 11, 2025

Country Inn & Suites by Radisson, Gainesville, FL
4015 Sw 43rd St, Gainesville, FL
Fully refundable
$91 nightly
The price is $102 total per night from Dec 7 to Dec 8
$102 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Staffing, clean, quiet and great location
Reviewed on Nov 12, 2025

La Quinta by Wyndham Gainesville
908 NW 69 Terrace, Gainesville, FL
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $102 total per night from Nov 16 to Nov 17
$102 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
I was impressed how clean the room was. The staff was accommodating and pleasant. I enjoyed my stay.
Reviewed on Nov 13, 2025

Sleep Inn & Suites University/Shands
4110 SW 40th Boulevard Gainesville FL
Fully refundable
$81 nightly
The price is $91 total per night from Dec 7 to Dec 8
$91 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Good breakfast
Reviewed on Nov 12, 2025

Best Western Gateway Grand
4200 NW 97th Blvd, Gainesville, FL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Nov 23 to Nov 24
$105 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
Wonderful place to stay, very friendly staff, clean and quiet, and breakfast!
Reviewed on Nov 7, 2025

HOM Hotel Gainesville, SureStay Collection by Best Western
3905 Sw 43Rd St, Gainesville, FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Nov 16 to Nov 17
$96 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Felt safe and comfortable
Reviewed on Nov 12, 2025

Comfort Inn University
3440 SW 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $91 total per night from Nov 24 to Nov 25
$91 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Very happy with our room and convenience to get around the city
Reviewed on Nov 11, 2025

DoubleTree by Hilton Gainesville
3726 Sw 40th Blvd Gainesville FL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Nov 23 to Nov 24
$101 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and free WiFi. A terrace, a garden, and a ...
Perfect place to stay for The Fest. Plenty of walking-distance food available. Very quiet, nice pool, great room.
Reviewed on Nov 7, 2025

Red Roof Inn PLUS+ Gainesville
3500 Southwest 42nd St, Gainesville, FL
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Nov 23 to Nov 24
$68 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock ...
Friendly staff, last king bed, clean room
Reviewed on Nov 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Fe hotel reviews by fellow wanderers

Red Roof Inn PLUS+ Gainesville
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Friendly staff, last king bed, clean room"
A verified traveler stayed at Red Roof Inn PLUS+ Gainesville
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