Book Motel 6 rooms in Upstate South Carolina
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top hotels by Motel 6 in Upstate South Carolina

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Greenville, SC

Motel 6 Greenville, SC - I-85 Near Downtown

Motel 6 Simpsonville, SC - Greenville
A Travel Guide To Motel 6 Hotels In Upstate South Carolina
You deserve a travel experience that exceeds your expectations and Motel 6 hotels in Upstate South Carolina can make sure that happens. While you’re vacationing, or even traveling for business, it’s all about you. You shouldn’t have any worries or concerns when you’re on the road, which is why you always choose to stay in accommodations you know and trust.
If you’re ready for excellent customer service at a hotel with a solid reputation, then you know where to go. These hotels will always treat you well, from the thread count of your sheets to the stocked minibar for all your snacking needs. When you’re ready to explore, head out to discover the local sights and get recommendations from the hotel staff on the best restaurants, too. Upstate South Carolina Motel 6 hotels are the perfect place for your getaway. Many are conveniently located near parks, shopping, restaurants, nightlife, and downtown, giving you the luxury of convenience at an affordable price.
If you think this might tip the budget scale to heavy, don’t worry--Travelocity offers cheap Motel 6 hotels in Upstate South Carolina. You get more than comfortable accommodations for a very reasonable price. Book your stay through us now and receive special online promotions, discounts, and offers for future travel plans.
Recent Upstate South Carolina hotel reviews by fellow wanderers

Best Western Plus Greenville I-385 Inn & Suites
"Hotel was nicely decorated for fall (halloween theme). Staff was friendly and helpful. Breakfast was good with nice selection."
More ways to wander Upstate South Carolina
Explore More Ways to Travel with Travelocity
- Hotels in Easley
- Hotels in Duncan
- Hotels near Conestee Nature Preserve
- Hotels near Clemson University
- Hotels in Clemson
- The Shepherd Hotel Downtown Clemson
- Hotels near Bon Secours Wellness Arena
- Hotels in Anderson
- Lakeside Lodge Clemson
- Clemson University's James F Martin Inn
- Smoking in Greenville
- Motel 6 Greenville SC
- Pet Friendly in Greenville
- Spa in Greenville
- stayAPT Suites Greenville-Haywood Mall
- The Westin Poinsett Greenville
- Hotels in Greenville
- Free Airport Transportation in Greenville - Spartanburg
- Hot Tub in Greenville - Spartanburg
- InTown Suites Extended Stay Greenville SC - I-85 Mauldin
- InTown Suites Extended Stay Greenville SC - Wade Hampton
- La Quinta Inn & Suites in Greenville - Spartanburg
- Mint House Greenville Downtown by Kasa
- Motel 6 Greenville SC - I-85 Near Downtown
- Hotels near Greenville SC
- OYO Rooms in Greenwood
- Motel 6 in Greer
- Hotels in Greer
- Hotels near Haywood Mall
- Hotels near Heritage Park
- Hotels near Memorial Stadium
- Hotels in Piedmont
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels in Seneca
- Aparthotels in Simpsonville
- Best Western in Simpsonville
- Motel 6 Simpsonville SC - Greenville
- Hotels in Simpsonville
- Aimbridge Hospitality in Spartanburg
- Motel 6 in Spartanburg
- Red Roof Inn in Spartanburg
- Hotels in Spartanburg
- Hotels near The Peace Center
- Hotels in Travelers Rest
- Hotels near Tyger River Park
- Agritourism in Upstate South Carolina
- Bedandbreakfast in Upstate South Carolina
- Cabins in Upstate South Carolina
- Aparthotels in Upstate South Carolina
- Adults Only in Upstate South Carolina
- Beach in Upstate South Carolina
- Boutique in Upstate South Carolina
- Hilton Hotels in Upstate South Carolina
- Free Airport Transportation in Upstate South Carolina
- Hot Tub in Upstate South Carolina
- Indoor Pool in Upstate South Carolina
- Pet Friendly in Upstate South Carolina
- Romantic in Upstate South Carolina
- Ski in Upstate South Carolina
- Houseboats in Upstate South Carolina
- Lodges in Upstate South Carolina
- Caravanparks in Upstate South Carolina
- Hotels near WestGate Mall
- Indoor Pool in Greenville
- Hot Tub in Greenville
- Balcony in Greenville
- Grand Bohemian Lodge Greenville Autograph Collection
- Drury Inn & Suites Greenville
- Budget in Greenville
- Aparthotels in Greenville
- Greenville Downtown Hotels
- River View Hotels in Greenville Downtown
- Hotels near Greenville Convention Center
- Cabins in Greenville
- Hotels near Fred W Symmes Chapel
- Hotels near Fluor Field at the West End
- Hotels near Falls Park on the Reedy
- Flights to Greenville - Spartanburg
- Flights from Greenville SC
- Flights from Windsor Locks (BDL) to Greer (GSP)
- Flights from Boston (BOS) to Greer (GSP)
- Flights from Dallas (DFW) to Greer (GSP)
- Flights from Detroit (DTW) to Greer (GSP)
- Flights from Newark (EWR) to Greer (GSP)
- Flights from West Harrison (HPN) to Greer (GSP)
- Flights from Jamaica (JFK) to Greer (GSP)
- Flights from Los Angeles (LAX) to Greer (GSP)
- Flights from Flushing (LGA) to Greer (GSP)
- Flights from Orlando (MCO) to Greer (GSP)
- Flights from Chicago (ORD) to Greer (GSP)
- Flights from Norfolk (ORF) to Greer (GSP)
- Flights from Portland (PDX) to Greer (GSP)
- Flights from Philadelphia (PHL) to Greer (GSP)
- Flights from Tampa (TPA) to Greer (GSP)



