Book Hotels in Lithium, MO
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Top Lithium hotels

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
$326 nightly
The price is $347 total per night from Jul 20 to Jul 21
$347 total
Jul 20 - Jul 21
Total includes taxes and fees
This farm stay features a water park and laundry facilities.
"We had such a wonderful anniversary weekend at the silo. It was beautiful and well maintained, both inside and out. Very well stocked kitchen, and plenty of towels. It was so peaceful sitting on the porch swing with a cup of coffee and driving to the nearby wineries was great. We even stopped by ..."
Reviewed on Jun 17, 2025

Missouri Castle w/ Private Lake, Pool & 100 Acres!
Saint Mary
This vacation home features a garden, laundry facilities, and barbecue grills.
Beautiful and peaceful setting
"My family of 14 people needed a place for all of us to stay for the holidays. The twin turrets was a great fit for what we needed. Everyone had their own bed, the bathrooms took a little time to get showers scheduled, since there are only 2 showers, but it worked out. The home was fun to explore ..."
Reviewed on Jan 5, 2025

Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
Ste. Genevieve
A water park and an indoor pool are featured at this smoke-free vacation home. Families will appreciate the arcade/game room, barbecue grills, and childcare. ...
Your own private resort
"We were an extended family (infants to adults) getting together for a long weekend. The house is exactly as described and as the pictures show. The absolute best VRBO home we have ever stayed in! The house includes everything you may ever need and would have to go buy at other rentals. The space ..."
Reviewed on Jun 29, 2025

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St, Perryville, MO
Fully refundable
$95 nightly
The price is $109 total per night from Jul 20 to Jul 21
$109 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Staff was helpful"
Reviewed on Jul 15, 2025

Baymont by Wyndham Chester IL
2150 State Street, Chester, IL
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $102 total per night from Aug 14 to Aug 15
$102 total
Aug 14 - Aug 15
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Very private"
Reviewed on Jul 11, 2025

Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32, Ste Genevieve, MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $97 total per night from Jul 20 to Jul 21
$97 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Gross cleaning service in front of guests at bkfst
"The first morning we ate breakfast (24th) as we were in the breakfast room I witnessed a female cleaning the area. She used a rag to scrub at the floor in front of the coffee machine. Nothing unusual, but I kept watching. She then stood up, rinsed out the rag then immediately started to wipe down ..."
Reviewed on Jun 27, 2025

Super 8 by Wyndham Perryville
1119 Vincent Dr, Perryville, MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Jul 24 to Jul 25
$78 total
Jul 24 - Jul 25
Total includes taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Cleanliness was good. Staff was helpful."
Reviewed on Jul 14, 2025

Days Inn by Wyndham Perryville
1500 Liberty Street, Perryville, MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 20 to Jul 21
$87 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Great walking area for my dog"
Reviewed on May 29, 2025

Quality Inn Perryville I-55
1517 S. Perryville Blvd., Perryville, MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 24 to Jul 25
$87 total
Jul 24 - Jul 25
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock ...
"The room was clean and comfortable"
Reviewed on Jun 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lithium hotel reviews by fellow wanderers

Holiday Inn Express & Suites Perryville by IHG
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Staff was helpful "
A verified traveler stayed at Holiday Inn Express & Suites Perryville by IHG
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An Attraction
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Mark Twain National Forest
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Sainte Genevieve Winery
- Hotels near Hawn State Park
- Hotels near Crown Valley Winery
- Hotels near Popeye Museum
- Hotels near Fort Kaskaskia
- Hotels near Perryville Country Club
- Hotels near Felix Valle House State Historic Site
- Hotels near Pierre Menard Home
- Hotels near Elzie C. Segar Memorial Park
- Hotels near Bolduc House Museum
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