Explore 64 Luxury Hotels in Key West

Name: Fairfield by Marriott Inn & Suites Key West at The Keys Collection
Price range: $171 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Key West

H2O Suites - Adults Only

1212 Simonton Street Key West FL

$419 nightly

$471 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...

9.8/10 Exceptional! (674 reviews)

"Beautiful Resort. Very disappointing staff. Upon arrival, the person at the desk was annoyed & stated that it was too early for checkin. As I travel the world, I have never been greeted this way. The usual response is that if the room is not ready you may use the resort until which time the room ..."

Reviewed on Nov 7, 2026

Hilton Key West Resort & Marina

5950 Peninsular Avenue Key West FL

Fully refundableReserve now, pay when you stay

$170 nightly

$191 total

Nov 15 - Nov 16

Total with taxes and fees

A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas ...

9/10 Wonderful! (1,795 reviews)

"Fire alarm went off at 3 AM on Novembe 5th, but the siren could not be heard at all inside room 2306 due to the front vestibule. I only realized what was happening when I looked out the window and saw a crowd outside. There was absolutely zero communication or direction from hotel staff and no fire ..."

Reviewed on Nov 7, 2026

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL

Fully refundableReserve now, pay when you stay

$286 nightly

$321 total

Nov 23 - Nov 24

Total with taxes and fees

A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...

8.4/10 Very Good! (1,011 reviews)

"Most amazing experience."

Reviewed on Nov 8, 2026

The Marker Key West Harbor Resort

200 William Street Key West FL

Fully refundable

$298 nightly

$335 total

Nov 16 - Nov 17

Total with taxes and fees

This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL

Fully refundableReserve now, pay when you stay

$268 nightly

$302 total

Nov 30 - Dec 1

Total with taxes and fees

A full-service spa, 3 outdoor pools, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the 2 conference rooms, free WiFi ...

Seashell Motel

718 South Street Key West FL

Fully refundableReserve now, pay when you stay

$193 nightly

$217 total

Nov 18 - Nov 19

Total with taxes and fees

This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. There's luggage storage and multilingual staff can provide around-the-clock ...

Southernmost House - Adult Exclusive

1400 Duval Street Key West FL

$352 nightly

$396 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self ...

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

3852 North Roosevelt Boulevard Key West FL

Fully refundableReserve now, pay when you stay

$152 nightly

$171 total

Nov 15 - Nov 16

Total with taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...

Don't see what you're looking for?

See all available properties in Key West

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Key West

Ocean Key Resort - A Noble House Resort

Zero Duval St. Key West FL

$326 nightly

$367 total

Nov 22 - Nov 23

Total with taxes and fees

9.2/10 Wonderful! (1,001 reviews)

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.

Key West hotels essential information

Accommodation	2,643 hotels
Lowest Price	$171
Highest Price	$471
Popular hotels	Hilton Key West Resort & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House - Adult Exclusive, Fairfield by Marriott Inn & Suites Key West at The Keys Collection