Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$709 nightly
The price is $798 total per night from Apr 5 to Apr 6
$798 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (588 reviews)
Very nice, very clean with great staff and convenient parking. The "private" pools are all in a courtyard so you can make awkward eye contact with the

Reviewed on Mar 3, 2026

Opens in a new windowH2O Suites - Adults Only
Santa Maria Suites

Santa Maria Suites

1401 Simonton St Key West FL
$617 nightly
The price is $695 total per night from Apr 14 to Apr 15
$695 total
Apr 14 - Apr 15
Total with taxes and fees
This smoke-free resort features 2 outdoor pools, a gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. There's a poolside ...
9.6/10 Exceptional! (1,001 reviews)
Wonderful pool

Reviewed on Mar 13, 2026

Opens in a new windowSanta Maria Suites
Southernmost House

Southernmost House

1400 Duval Street Key West FL
$432 nightly
The price is $486 total per night from Apr 12 to Apr 13
$486 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self ...
9.4/10 Exceptional! (1,002 reviews)
Great place to stay overlooking the water with nice pool. Staff is great. Location is great, close to everything but not in the middle of the craziness of Duvall Street. Room was good. General property could use some sprucing up but doesn’t take away from the overall pluses of the place.

Reviewed on Mar 13, 2026

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundableReserve now, pay when you stay
$586 nightly
The price is $659 total per night from Apr 5 to Apr 6
$659 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9.2/10 Wonderful! (1,002 reviews)
Yes , it is always convenient to everything.

Reviewed on Mar 14, 2026

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$369 nightly
The price is $415 total per night from Apr 13 to Apr 14
$415 total
Apr 13 - Apr 14
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
9/10 Wonderful! (1,823 reviews)
Room was nice, but the toilet had a terrible smell the last day. It was clean, but stunk of what seemed like sewer gas coming up. It was gross.

Reviewed on Mar 14, 2026

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

3852 North Roosevelt Boulevard Key West FL
Fully refundableReserve now, pay when you stay
$308 nightly
The price is $347 total per night from Apr 12 to Apr 13
$347 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.6/10 Excellent! (1,003 reviews)
😀😀👍👍

Reviewed on Mar 14, 2026

Opens in a new windowFairfield by Marriott Inn & Suites Key West at The Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
$549 nightly
The price is $618 total per night from Mar 16 to Mar 17
$618 total
Mar 16 - Mar 17
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.4/10 Very Good! (579 reviews)
Had a great time!

Reviewed on Mar 14, 2026

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$318 nightly
The price is $358 total per night from Apr 1 to Apr 2
$358 total
Apr 1 - Apr 2
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
8/10 Very Good! (1,001 reviews)
Good location

Reviewed on Mar 14, 2026

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,707 hotels
Lowest Price
$347
Highest Price
$798
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield by Marriott Inn & Suites Key West at The Keys Collection, Santa Maria Suites

Popular Luxury Stays in Key West

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